Title:The Effects of Vitamin Therapy on ASD and ADHD: A Narrative Review
Volume: 22
Issue: 5
Author(s): Mohadeseh Poudineh, Sadaf Parvin, Mehrnia Omidali, Farhad Nikzad, Fatemeh Mohammadyari, Fatemeh Sadeghi Poor Ranjbar, Fayaz Rasouli, Sepehr Nanbakhsh and Sepehr Olangian-Tehrani*
Affiliation:
- School of Medicine, Iran University of
Medical Sciences, Tehran, Iran
- Avicennet, Tehran, Iran
Keywords:
Autism spectrum disorder, attention deficit hyperactivity disorder, vitamin, omega-3, iron supplements, zinc supplements.
Abstract: The effects of a sufficient amount of vitamins and nutrients on the proper function of the
nervous system have always been regarded by scientists. In recent years, many studies have been done
on controlling or improving the symptoms of neurological and behavioral disorders created by changes
in the level of vitamins and other nutrition, such as omega-3 and iron supplements. Autism spectrum
disorder (ASD) is a neurodevelopmental disorder that disrupts individual communication, especially
in social interactions. Its symptoms include anxiety, violence, depression, self-injury, trouble
with social contact and pervasive, stereotyped, and repetitive behavior. ASD is most noticeable in early
childhood. Attention Deficit Hyperactivity Disorder (ADHD) is a lasting pattern of inattention with
or without hyperactivity that causes functional disruption in daily life. ADHD symptoms included;
impulsivity, hyperactivity, inattention, restlessness, talkativeness, excessive fidgeting in situations
such as sitting, meetings, lectures, or at the movies, boredom, inability to make decisions, and procrastination.
The exact etiology of ADHD has not yet been found, but several observations have assumed
the reduced function of the brain leads to deficits in motor planning and cognitive processing. It has
been shown that Pro-inflammatory cytokines and oxidative stress biomarkers could be increased in
both ASD and ADHD. Several studies have been done to illustrate if vitamins and other dietary supplements
are effective in treating and preventing ASD and ADHD. In this review, we aim to evaluate
the effects of vitamins and other dietary supplements (e.g., melatonin, zinc supplements, magnesium
supplements) on ASD and ADHD.