Title:Xenobots: Applications in Drug Discovery
Volume: 23
Issue: 14
Author(s): Nilay Solanki*, Sagar Mahant, Swayamprakash Patel, Mehul Patel, Umang Shah, Alkesh Patel, Hardik Koria and Ashish Patel
Affiliation:
- Department of Pharmacology, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology,
CHARUSAT Campus, Changa, Gujarat, India
Keywords:
Xenopus laevis, xenobots, in silico, in vivo, bioengineering, medical research, pharmaceutical research.
Abstract: This review work discusses the applications of xenobots in drug discovery. These are the
world's first tiny robots that are living. Robots are built of metals and other things that benefit humans
to solve various issues; however, in this case, small xenobots were built utilizing Xenopus
laevis, frog embryonic stem cells in the blastocyte stage. Xenobots were created by combining bioscience,
artificial intelligence, and computer science. Artificial intelligence constructs several forms
of design in an in vitro, In-silico model, after which software analyzes the structure; the most substantial
and most noticeable forms are filtered out. Later in vivo development create the design of the
Petri plate using the MMR solution and makes the same form as the in silico approach. Ultimately
evaluation done based on the behavior, movement, function, and features of xenobots. Xenobots are
employed in medical research, pharmaceutical research to evaluate novel dosage forms, also useful
for biotechnological and environmental research. Xenobots can be utilized to cure neurodegenerative
disorders such as Alzheimer's, Parkinson's disease, and cancer-related issues because of their selfrepairing
properties, which allow them to repair normal damaged cells, and convey drugs to their
specific target, and reduce cytotoxicity in mostly malignancy circumstances. In the future, new approaches
will be employed to treat chronic illnesses and their complications.
