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Mini-Reviews in Organic Chemistry

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ISSN (Online): 1875-6298

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Mini-Review Article

Advancements in Schiff Bases of 1H-Indole-2,3dione: A Versatile Heterocyclic Compound in Pharmacological Field

Author(s): Savitha D. Pradeep and Puzhavoorparmbil V. Mohanan*

Volume 20, Issue 1, 2023

Published on: 13 May, 2022

Page: [45 - 54] Pages: 10

DOI: 10.2174/1570193X19666220309142035

Price: $65

Open Access Journals Promotions 2
Abstract

Heterocyclic compounds have specific structural peculiarities, imparting immense applications in various fields. This study has explored the medicinal importance of a captive heterocyclic compound, 1H-Indole-2,3dione, commonly known as isatin. The flexibility in the structure of isatin makes it more innovative to have applications in the biological and analytical fields. In this minireview, we have discussed Schiff bases of isatin having activities, such as antidiabetic, antioxidant, antidiabetic, antimalarial, antiviral, anticonvulsant, anti-inflammatory and analgesic activity, and also the importance of this compound in various fields based on the reports mainly focussed on the current and past couple of years.

Keywords: Isatin, Schiff bases, biological applications, heterocyclic compounds, antidiabetic, antioxidant.

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