Title:Role of Cannabinoids in Various Diseases: A Review
Volume: 23
Issue: 11
Author(s): Simran Kaur, Nikita Sharma and Arpita Roy*
Affiliation:
- Department of Biotechnology, School of Engineering & Technology, Sharda University, Greater Noida, India
Keywords:
Cannabis sativa, endocannabinoid system, cannabinoids, therapeutic applications, infectious diseases, neurodegenerative diseases.
Abstract:
Background: The plant, Cannabis sativa, is heavily explored and researched with many industrial
and pharmaceutical applications. The medicinal and therapeutic role of Cannabis sativa has been
summarized in the paper, citing its mechanism of action and influence on the human body. Diseases like
metabolic disorders, infectious diseases, and psychological disorders pose negative and long-term drastic
effects on the body like neurodegeneration and other chronic system failures. Several existing studies
have proved its effectiveness against such diseases.
Objectives: This review aims to provide an overview of the role of cannabinoids in various diseases like
metabolic disorders, infectious diseases, and psychological disorders.
Methods: Various e-resources like Pubmed, Science Direct, and Google Scholar were thoroughly
searched and read to make an informative, comprehensive manuscript. Here we tried to summarize the
therapeutic aspect of Cannabis sativa and its bioactive compound cannabinoids with respect to various
diseases.
Results: This review highlights the various constituents which are present in Cannabis sativa, the endocannabinoid
system, and the role of cannabinoids in various diseases.
Conclusion: Recent research on Cannabis has suggested its role in neurodegenerative diseases, inflammation,
sleep disorders, pediatric diseases, and their analgesic nature. Therefore, the authors majorly focus
on the therapeutic aspect of Cannabis sativa in various diseases. The focus is also on the endocannabinoid
system (ECS) and its role in fighting or preventing bacterial, parasitic, fungal, and viral infections.