Title:Metabolic Syndrome, Alzheimer’s Disease, and Covid 19: A Possible Correlation
Volume: 18
Issue: 12
Author(s): Carmine Finelli*
Affiliation:
- Department of Internal Medicine, ASL Napoli 3 SUD, Napoli, Italy
Keywords:
Metabolic syndrome , Alzheimer’s disease , COVID-19 , inflammation , immunity , obesity , NAFLD , dementia .
Abstract:
Age and comorbidities are key indicators of hospital admission, serious illness, and mortality
in COVID-19 patients. Patients with age-related comorbidities, such as cardiovascular disease,
hypertension, diabetes, chronic kidney disease, NAFLD, obesity, and metabolic syndrome,
are more likely to require hospitalization and suffer severe sickness of COVID-19. Patients with
Alzheimer’s disease and risk factors associated with dementia may also be more vulnerable to serious
COVID-19 infection. Peripheral inflammation, including in patients who recover from illness,
may promote the course of neurodegenerative disorders through neuroinflammatory pathways.
The aim of this study is to examine the impact of COVID-19 on immunity in patients with age-related
diseases such as metabolic syndrome and Alzheimer’s disease and also to hypothesize the possible
correlation between metabolic syndrome, Alzheimer’s disease, and COVID-19. Identifying
the mechanisms that explain the complicated interaction between metabolic syndrome,
Alzheimer’s disease, COVID-19, inflammation, and immunity could be crucial to designing effective
pharmacological therapies and procedures. This study adds to our basic information about the
new coronavirus by synthesizing current knowledge of these linkages. To reduce inflammation and
enhance immunity, patients should acquire good lifestyle practices. Walking, breathing exercises,
and a nutritious diet all help in improving lung capacity and immunity.
Future research into novel therapeutics for patients with metabolic syndrome, Alzheimer’s disease,
and COVID-19 inflammation and immunology is encouraged by this paper.
