Generic placeholder image

Current Pediatric Reviews

Editor-in-Chief

ISSN (Print): 1573-3963
ISSN (Online): 1875-6336

Research Article

Effect of Vaginal Delivery on Lactose Content of Human Milk

Author(s): Leila Zeynali, Roghaiyeh Nourizadeh, Azizeh Farshbaf Khalili, Mohammadbagher Hosseini, Assef Khalili and Sevil Hakimi*

Volume 18, Issue 2, 2022

Published on: 14 January, 2022

Page: [138 - 143] Pages: 6

DOI: 10.2174/1573396317666211206123648

Price: $65

Abstract

Objective: The macronutrients of human milk are considered essential nutritional sources in the first few months of a newborn’s life. The present study aimed to investigate the effect of delivery mode on the macronutrients of human milk.

Methods: This retrospective cohort study was conducted on 102 women who gave birth by cesarean section or vaginal delivery between September 2019 and November 2019. The participants were requested to provide their milk samples on day 15 ± 1 after childbirth.

Results: There were no significant differences between the two groups (cesarean and vaginal delivery) regarding the sociodemographic characteristics and intake of fat, carbohydrate, protein, and energy. The lactose level was significantly higher in women who gave birth by vaginal delivery (adjusted mean difference, 1.2 (95 % CI 0.02- 1.82)). For other macronutrients, there were no statistically significant differences between the two groups.

Conclusion: The vaginal delivery might influence the mature milk lactose level.

Keywords: Lactose, macronutrients, mature human milk, vaginal delivery, pregnancy, breast milk.

Graphical Abstract
[1]
Fewtrell MS, Morgan JB, Duggan C, et al. Optimal duration of exclusive breastfeeding: What is the evidence to support current recommendations? Am J Clin Nutr 2007; 85(2): 635S-8S.
[http://dx.doi.org/10.1093/ajcn/85.2.635S] [PMID: 17284769]
[2]
Ma JR, Wang DH. Epigenetic effects of human breastfeeding. Chinese J Contemp Pediatr 2016; 18(10): 926-30.
[3]
Ballard O, Morrow AL. Human milk composition: Nutrients and bioactive factors. Pediatr Clin North Am 2013; 60(1): 49-74.
[http://dx.doi.org/10.1016/j.pcl.2012.10.002] [PMID: 23178060]
[4]
Yang T, Zhang Y, Ning Y, et al. Breast milk macronutrient composition and the associated factors in urban Chinese mothers. Chin Med J (Engl) 2014; 127(9): 1721-5.https://pubmed.ncbi.nlm.nih.gov/24791881/
[PMID: 24791881]
[5]
Andreas NJ, Kampmann B, Mehring Le-Doare K. Human breast milk: A review on its composition and bioactivity. Early Hum Dev 2015; 91(11): 629-35.
[http://dx.doi.org/10.1016/j.earlhumdev.2015.08.013] [PMID: 26375355]
[6]
Wu X, Jackson RT, Khan SA, Ahuja J, Pehrsson PR. Human milk nutrient composition in the United States: Current knowledge, challenges, and research needs. Curr Dev Nutr 2018; 2(7): nzy025.
[http://dx.doi.org/10.1093/cdn/nzy025] [PMID: 30087951]
[7]
Lönnerdal B. Bioactive proteins in human milk: Mechanisms of action. J Pediatr 2010; 156(2)(Suppl.): S26-30.
[http://dx.doi.org/10.1016/j.jpeds.2009.11.017] [PMID: 20105661]
[8]
Lönnerdal B, Erdmann P, Thakkar SK, Sauser J, Destaillats F. Longitudinal evolution of true protein, amino acids and bioactive proteins in breast milk: A developmental perspective. J Nutr Biochem 2017; 41: 1-11.
[http://dx.doi.org/10.1016/j.jnutbio.2016.06.001] [PMID: 27771491]
[9]
Chang N, Jung JA, Kim H, et al. Macronutrient composition of human milk from Korean mothers of full term infants born at 37-42 gestational weeks. Nutr Res Pract 2015; 9(4): 433-8.
[http://dx.doi.org/10.4162/nrp.2015.9.4.433] [PMID: 26244084]
[10]
Kent JC, Mitoulas LR, Cregan MD, Ramsay DT, Doherty DA, Hartmann PE. Volume and frequency of breastfeedings and fat content of breast milk throughout the day. Pediatrics 2006; 117(3): e387-95.
[http://dx.doi.org/10.1542/peds.2005-1417] [PMID: 16510619]
[11]
Kurniati AM, Sunardi D, Sungkar A, Bardosono S, Kartinah NT. Associations of maternal body composition and nutritional intake with fat content of Indonesian mothers’ breast milk. Paediatr Indones 2016; 56(5): 298.
[12]
Yu Z, Palkovicova L, Drobna B, et al. Comparison of organochlorine compound concentrations in colostrum and mature milk. Chemosphere 2007; 66(6): 1012-8.
[http://dx.doi.org/10.1016/j.chemosphere.2006.07.043] [PMID: 17007906]
[13]
Mangel L, Mimouni FB, Feinstein-Goren N, Lubetzky R, Mandel D, Marom R. The effect of maternal habitus on macronutrient content of human milk colostrum. J Perinatol 2017; 37(7): 818-21.
[http://dx.doi.org/10.1038/jp.2017.51] [PMID: 28406487]
[14]
Dizdar EA, Sari FN, Degirmencioglu H, et al. Effect of mode of delivery on macronutrient content of breast milk. J Matern Fetal Neonatal Med 2014; 27(11): 1099-102.
[http://dx.doi.org/10.3109/14767058.2013.850486] [PMID: 24107128]
[15]
Azami-Aghdash S, Ghojazadeh M, Dehdilani N, Mohammadi M, Asl Amin Abad R. Prevalence and causes of cesarean section in Iran: Systematic review and meta-analysis. Iran J Public Health 2014; 43(5): 545-55.
[PMID: 26060756]
[16]
Bahadori F, Hakimi S, Heidarzade M. The trend of caesarean delivery in the Islamic Republic of Iran. Eastern Mediter Health J 2013; 19(Suppl 2): S67.
[http://dx.doi.org/10.26719/2013.19.Supp3.S67]
[17]
Saarela T, Kokkonen J, Koivisto M. Macronutrient and energy contents of human milk fractions during the first six months of lactation. Acta Paediatr 2005; 94(9): 1176-81.
[http://dx.doi.org/10.1111/j.1651-2227.2005.tb02070.x] [PMID: 16203669]
[18]
Mahan LK, Raymond JL, Escott-Stump S. Krause’s Food & the Nutrition Care Process-E-Book. Elsevier Health Sciences 2013.
[19]
Schaafsma G. Lactose and lactose derivatives as bioactive ingredients in human nutrition. Int Dairy J 2008; 18(5): 458-65.
[http://dx.doi.org/10.1016/j.idairyj.2007.11.013]
[20]
Plaza-Díaz J, Fontana L, Gil A. Human milk oligosaccharides and immune system development. Nutrients 2018; 10(8): 1038.
[http://dx.doi.org/10.3390/nu10081038] [PMID: 30096792]
[21]
Cederlund A, Kai-Larsen Y, Printz G, et al. Lactose in human breast milk an inducer of innate immunity with implications for a role in intestinal homeostasis. PLoS One 2013; 8(1): e53876.
[http://dx.doi.org/10.1371/journal.pone.0053876] [PMID: 23326523]
[22]
Khan S, Hepworth AR, Prime DK, Lai CT, Trengove NJ, Hartmann PE. Variation in fat, lactose, and protein composition in breast milk over 24 hours: Associations with infant feeding patterns. J Hum Lact 2013; 29(1): 81-9.
[http://dx.doi.org/10.1177/0890334412448841] [PMID: 22797414]
[23]
Evans KC, Evans RG, Royal R, Esterman AJ, James SL. Effect of caesarean section on breast milk transfer to the normal term newborn over the first week of life. Arch Dis Child Fetal Neonatal Ed 2003; 88(5): F380-2.
[http://dx.doi.org/10.1136/fn.88.5.F380] [PMID: 12937041]
[24]
Hahn WH, Song JH, Song S, Kang NM. Do gender and birth height of infant affect calorie of human milk? An association study between human milk macronutrient and various birth factors. J Matern Fetal Neonatal Med 2017; 30(13): 1608-12.
[http://dx.doi.org/10.1080/14767058.2016.1219989] [PMID: 27482600]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy