摘要
碳点(CDs)是一种新兴的可替代传统荧光剂的纳米剂,由于其独特的优势,如易于合成、大规模生产、成本低、光致发光、光稳定性好、易功能化、充分的生物相容性、良好的纳米载体以及产生活性氧或热的能力,引起了科学家对生物医学应用的兴趣。在此基础上,本文提出了利用荧光CDs在体外和体内生物成像、成像辅助传感和成像引导治疗方面的成像辅助生物医学应用的观点。对其在生物医学应用中的潜力和挑战的意见进行了讨论,以开发和进一步改进光盘,使其在各种图像辅助生物医学应用中得到广泛利用。
关键词: 碳点、生物成像、成像辅助传感、成像引导治疗、生物医学应用、光致发光。
Current Medicinal Chemistry
Title:Fluorescent Carbon Dots as Prospective Nanoagents for Imaging-assisted Biomedical Applications
Volume: 29 Issue: 23
关键词: 碳点、生物成像、成像辅助传感、成像引导治疗、生物医学应用、光致发光。
摘要: Carbon dots (CDs), an emerging nanoagent providing an alternative to conventional fluorescent agents, are sparking the scientist’s interest in biomedical applications owing to their unique advantages, including ease of synthesis, large scale production, low cost, prominent photoluminescence, good photostability, easy functionalization, sufficient biocompatibility, good nanocarrier, and excellent ability to generate reactive oxygen species or heat. Herein, this perspective provides a viewpoint about imaging-assisted biomedical applications using fluorescent CDs regarding in vitro and in vivo bioimaging, imaging-assisted sensing, and imaging-guided therapy. The opinions about their potential and challenges in applicable biomedical applications are discussed to develop, further ameliorated CDs for their intense exploitation in diverse imaging-assisted biomedical applications.
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Fluorescent Carbon Dots as Prospective Nanoagents for Imaging-assisted Biomedical Applications, Current Medicinal Chemistry 2022; 29 (23) . https://dx.doi.org/10.2174/0929867328666211129121958
DOI https://dx.doi.org/10.2174/0929867328666211129121958 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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