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Current Psychopharmacology

Editor-in-Chief

ISSN (Print): 2211-5560
ISSN (Online): 2211-5579

Perspective

Cerebellum, GABA and Ataxia

Author(s): Robert Lalonde* and Catherine Strazielle

Volume 11, Issue 1, 2022

Published on: 10 December, 2021

Page: [5 - 6] Pages: 2

DOI: 10.2174/2211556010666211122155811

Abstract

Various clinical results are obtained regarding the effects of cerebellar GABA transmission on spinocerebellar ataxias. Based on animal studies, it is proposed that balanced GABAergic transmission between GABA and other neurotransmitters such as glutamate may lead to more promising results in treating such conditions.

Keywords: Gamma-aminobutyric acid, spinocerebellar ataxia, Friedreich’s ataxia, glucocorticoids, Golgi cells, cerebellum.

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