Title:Evaluation of the Fibromyalgia and Related Risk Factors in Patients with Advanced Kidney Failure Undergoing Hemodialysis
Volume: 18
Issue: 1
Author(s): Seyed Mostafa Seyedmardani*, Saeed Abkhiz, Azadeh Megrazi, Aarefeh Jafarzade and Golshan Kamali Zonouz
Affiliation:
- Department of Internal Medicine, Urmia University of Medical Sciences, Urmia, Iran
Keywords:
Fibromyalgia syndrome, hemodialysis, risk factors, kidney failure, rheumatologic disorders, hemodialysis.
Abstract: Background: Fibromyalgia syndrome (FMS) is defined as widespread and persistent
pain in the musculoskeletal system. There are limited reports regarding the prevalence of fibromyalgia
syndrome in patients with advanced kidney failure undergoing regular hemodialysis. Therefore,
this study aimed to evaluate the prevalence of fibromyalgia syndrome and its risk factors in a large
proportion of patients under the hemodialysis condition.
Materials and Methods: In this cross-sectional study, 293 patients who were admitted to the hemodialysis
ward were evaluated for fibromyalgia syndrome in an educational hospital. The questionnaire
was designed according to symptom severity score (SS score) and widespread pain index (WPI)
criteria. The correlation between FMS and various variables, including demographic, clinical,
and biochemistry biomarkers, was also precisely calculated by logistic regression. Data were analyzed
using SPSS v.17 statistics software.
Results: The results showed that, of 293 hemodialysis patients, 130 patients (44.4%) had fibromyalgia,
the mean age of patients with and without fibromyalgia was 61.09 ± 15.36 and 53.49 ± 15.38
years old, respectively (P = 0.001). Moreover, there was a significant difference in terms of gender
among patients with fibromyalgia syndrome (P = 0.001). To note, there was no significant relationship
between the kidney failure etiopathogenesis, duration of dialysis, body mass index (BMI),
Kt/v index, history of peritoneal dialysis, and laboratory parameters with fibromyalgia in hemodialysis
patients (P > 0.05). However, our findings revealed that both age and gender could be considered
as the predictor variables associated with fibromyalgia in patients undergoing hemodialysis.
Conclusion: Taken together, in this study, we found that age and gender would be the critical factors
in terms of the fibromyalgia syndrome in patients undergoing hemodialysis.
