Title:Application of Stem Cell Therapy During the Treatment of HIV/AIDS and
Duchenne Muscular Dystrophy
Volume: 17
Issue: 7
Author(s): Lorraine Chitena, Keletso Masisi, Kabo Masisi, Tebogo E. Kwape and Goabaone Gaobotse*
Affiliation:
- Department of Biological Sciences and Biotechnology, Botswana International University of Science and Technology,
Private Bag 16, Palapye, Botswana
Keywords:
High active antiretroviral therapy, C-C chemokine receptor 5, antiretroviral treatment, pre-exposure prophylaxis, hematopoietic stem cells, induced pluripotent stem cells, muscular dystrophy, duchenne muscular dystrophy, melancholy stem cells.
Abstract: Treating diseases such as Muscular Dystrophy (MD) and HIV/AIDS pose several challenges
to the rapidly evolving field of regenerative medicine. Previously, stem cell therapy has
been said to affect the clinical courses of HIV/AIDS and MD, but, in practice, eradication or control
of these diseases was not achievable. The introduction of gene editing into stem cell therapy
has stimulated HIV/AIDS and MD cell therapy research studies substantially. Here, we review current
methods of treating HIV/AIDS and MD using stem cell therapy. This review also details the
use of different types of cells and methods in cell therapy and the modeling of new cell-based therapies
to treat Duchenne muscular dystrophy. We speculate that the effective use of stem cell therapy
in conjunction with other treatment therapies , such as steroids and rehabilitation , could improve
livelihood.