Title:Pharmacodynamic Stance of Phytoconstituents as a Gastric Ulcer
Protective Mechanism: An Overview
Volume: 22
Issue: 5
Author(s): Manish Pal Singh*, Viney Chawla, Darpan Kaushik, Pooja A Chawla and Siddhraj Singh Sisodia
Affiliation:
- Department of Pharmacology, Agra Public Pharmacy College, Agra, Uttar Pradesh, India
Keywords:
Gastric ulcer, gastroprotective, peptic ulcer, phytoconstituents, gastric mucus cell, cytoprotective.
Abstract: Various traditional herbal plants have been associated with unique
pharmacological actions. Natural parts as well as processed plant parts are known to
possess gastro-protective and gastro- mucosal healing property. Motive of this review
analysis is to explain the gastro-protective and gastro-mucosal healing property of
different herbal plants and their constituents indigenous to various regions of the globe
and elucidate mechanisms of the healing by their metabolic extracts. Moreover, an
attempt shall be made to explicate the possible molecular pharmacological targets
responsible for healing gastric ulcer activity. A thorough survey of literature has been
carried out from various scientific resources and using keywords like peptic ulcer
mechanism, gastro-protective agents, gastro-mucosal healing property, natural and
processed herbal drugs preventing peptic ulcers. This article will present a running
commentary on the prospects and potential of herbal plants exhibiting gastroprotective
activity and gastro-mucosal healing property.