Title:Body Mass Index and Waist Hip Ratio as a Risk Factor for Meningioma Incidence
Volume: 17
Issue: 7
Author(s): Heny Yuniarti*, Hertanto W. Subagio, Niken Puruhita, Etisa A. Murbawani, Annta K. Nugrohowati, Dody Priambada and Ajid Risdianto
Affiliation:
- Department of Clinical Nutrition, Diponegoro University-Kariadi General Hospital, Semarang,Indonesia
Keywords:
Meningioma, body mass index, waist-hip ratio, obesity, sex, age.
Abstract:
Background: Meningioma is a pathological condition in the central nervous system
(CNS), while obesity is defined as excess fat accumulation in the body, which is associated with
adverse effects on health. Obesity is characterized by an increase in the Body Mass Index (BMI)
and Waist Hip Ratio (WHR). Research on the relationship of BMI, and WHR with meningioma
has been widely carried out in various countries of Europe, however, it has not been done much
in the Asian countries, especially in Indonesia.
Objective: To prove BMI and WHR as risk factors for the incidence of meningioma after being
controlled by confounding variables of age and sex.
Methods: This is a case-control research involving 44 meningioma patients and 44 family members
as controls. The study was conducted at the outpatient clinic at Kariadi Doctors Hospital
from May 2019 to June 2019. We collected data including age, sex, BMI, and WHR. Bivariate
analysis using the Chi-square test and multivariate analysis with logistic regression was performed.
Results: Bivariate test results showed a significant relationship between meningioma and BMI (p
< 0.001), WHR (p < 0.001), and sex (p < 0.001). Multivariate test results found that the variables
that influence the incidence of meningioma the most were BMI, WHR, and sex.
Conclusion: Besides BMI, the increase of WHR and female sex are risk factors for meningioma
incidence.
