摘要
自(2α,3β)-2,3-二羟基齐墩烯-12-烯-28-酸(又称山楂酸)被发现以来,许多研究对其生物活性进行了研究,发现其具有促进健康和抵抗各种疾病的作用。本文重点介绍了山楂酸在心血管疾病、神经保护、糖尿病、癌症、炎症和病原体等方面的研究进展。山楂酸对疾病的细胞和动物模型均有积极作用。虽然山楂酸的作用机理尚未完全阐明,但山楂酸作为营养添加剂是可行的,具有药物开发的潜力。
关键词: 山楂酸,心血管疾病,神经保护,糖尿病,癌症,炎症,病原体
Current Drug Targets
Title:Review of the Biological Activity of Maslinic Acid
Volume: 22 Issue: 13
关键词: 山楂酸,心血管疾病,神经保护,糖尿病,癌症,炎症,病原体
摘要: Since the discovery of (2α,3β)-2,3-dihydroxyolean-12-en-28-oic acid, also known as maslinic acid, many studies have examined its biological activity, which has been shown to promote health and resist various diseases. This article focuses on previous research on maslinic acid and mainly reviews its reported effects on cardiovascular diseases, neuroprotection, diabetes, cancer, inflammation, and pathogens. Maslinic acid exerts positive effects on both cell and animal models of disease. Although its mechanism of action has not yet been completely elucidated, maslinic acid is feasible as a nutritional additive and has the potential to be developed as a drug.
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Review of the Biological Activity of Maslinic Acid, Current Drug Targets 2021; 22 (13) . https://dx.doi.org/10.2174/1389450122666210308111159
DOI https://dx.doi.org/10.2174/1389450122666210308111159 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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