Title:Chemical Diversity and Bioactivity of Marine Sponges of the Genus
Oceanapia: A Review
Volume: 19
Issue: 1
Author(s): Keisham S. Singh*Supriya Tilvi
Affiliation:
- Bioorganic Chemistry Laboratory, CSIR-National Institute of Oceanography, Dona Paula-403004, Goa,India
Keywords:
Marine sponges, alkaloids, Oceanapia sp., biological activity, ceramides, sphingolipids, acetylenic acids
Abstract: The marine sponges of the genus Oceanapia sp. is comprised of more than 50 species
and are distributed in the seas around the tropical and subtropical regions. They are mainly found in
the northern Indian oceans, Japan, and the south pacific coast. They are highly colored and known
to be a rich source of various secondary metabolites, particularly alkaloids. Several other secondary
metabolites are also reported from this genus which include terpenes, sphingolipids, ceramides, cerebrosides,
acetylenic acids, and thiocyanatins, etc. Many of these compounds isolated from this genus
exhibited various biological properties, including anticancer, antimicrobial, anti-HIV, ichthyotoxicity,
and nematocidal activities. Although several secondary metabolites have been reported
from this genus, a dedicated review of the chemicals and biological activities of this genus is so far
lacking. Keeping this in mind, this review describes the various chemical entities isolated from the
sponges of the genus Oceanapia, providing details of their chemical structures along with their reported
biological properties