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Current Chinese Science


ISSN (Print): 2210-2981
ISSN (Online): 2210-2914

Review Article Section: Analytical Chemistry

Therapeutic Benefit of Salvigenin Against Various forms of Human Disorders Including Cancerous Disorders: Medicinal Properties and Biological Application in the Modern Medicine

Author(s): Dinesh Kumar Patel*

Volume 1, Issue 3, 2021

Published on: 23 February, 2021

Page: [387 - 395] Pages: 9

DOI: 10.2174/2210298101666210224100246


Natural products have always been used in medicine for the discovery of new biological molecules against different types of human disorders. Crude drugs have been used in different systems of medicine, including Traditional Chinese Medicine and the Ayurvedic System of Medicine. From ancient time to this modern age, special emphasis has been given to the traditional knowledge of plants based products for the development of newer and better modern drugs. Traditional medicines are always better choices in the medicine and healthcare system by the people of developing countries for the treatment of human disorders. Polyphenolic compounds have been used in medicine due to their vast medicinal application and pharmacological activities. Flavonoidal class chemicals are the better examples of polyphenolic compounds, which have a 15- carbon skeleton chemical structure. Salvigenin is a pure flavonoid class phytochemical found to be present in the Salvia lachnocalyx, Salvia hydrangea and Plectranthus amboinicus and other medicinal plants and vegetables. Pharmacologically salvigenin has been found to have cytotoxic effects on various forms of cancer cells, such as colon adenocarcinoma, breast adenocarcinoma and glioblastoma. Further salvigenin has beneficial potential in the medicine for the treatment of diabetes and protects cells against oxidative stress. In order to know the therapeutic benefit of salvigenin in the medicine, here in the present study, all the scientific research data of salvigenin have been collected and analyzed for their biological significance in medicine. Extensive pharmacological investigation has been performed to know the better medicinal properties of the salvigenin in modern medicine. Analytical techniques used in the separation, isolation and identification of salvigenin have also been searched and presented in the present work. From the above-presented data, it was found that salvigenin has significant biological potential in medicine and could be used for the development of newer and better molecule or drugs against various forms of human disorders, including cancerous disorders.

Keywords: Salvigenin, human disorders, flavonoid, cancers, medicine, traditional medicine, modern medicine.

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