Title:Therapeutic Benefit of Salvigenin Against Various forms of Human Disorders Including Cancerous Disorders: Medicinal Properties and Biological Application in the Modern Medicine
Volume: 1
Issue: 3
Author(s): Dinesh Kumar Patel*
Affiliation:
- Department of Pharmaceutical Sciences, Faculty of Health Science, Sam Higginbottom University of Agriculture, Technology and Sciences Naini, Prayagraj, 211007, Uttar Pradesh,India
Keywords:
Salvigenin, human disorders, flavonoid, cancers, medicine, traditional medicine, modern medicine.
Abstract: Natural products have always been used in medicine for the discovery of new biological
molecules against different types of human disorders. Crude drugs have been used in different systems
of medicine, including Traditional Chinese Medicine and the Ayurvedic System of Medicine.
From ancient time to this modern age, special emphasis has been given to the traditional
knowledge of plants based products for the development of newer and better modern drugs. Traditional
medicines are always better choices in the medicine and healthcare system by the people of
developing countries for the treatment of human disorders. Polyphenolic compounds have been
used in medicine due to their vast medicinal application and pharmacological activities. Flavonoidal
class chemicals are the better examples of polyphenolic compounds, which have a 15-
carbon skeleton chemical structure. Salvigenin is a pure flavonoid class phytochemical found to be
present in the Salvia lachnocalyx, Salvia hydrangea and Plectranthus amboinicus and other medicinal
plants and vegetables. Pharmacologically salvigenin has been found to have cytotoxic effects
on various forms of cancer cells, such as colon adenocarcinoma, breast adenocarcinoma and glioblastoma.
Further salvigenin has beneficial potential in the medicine for the treatment of diabetes
and protects cells against oxidative stress. In order to know the therapeutic benefit of salvigenin in
the medicine, here in the present study, all the scientific research data of salvigenin have been collected
and analyzed for their biological significance in medicine. Extensive pharmacological investigation
has been performed to know the better medicinal properties of the salvigenin in modern
medicine. Analytical techniques used in the separation, isolation and identification of salvigenin
have also been searched and presented in the present work. From the above-presented data, it was
found that salvigenin has significant biological potential in medicine and could be used for the development
of newer and better molecule or drugs against various forms of human disorders, including
cancerous disorders.
