Title:Recent Trend in the Chemistry of Triazolopyrimidines and their Applications
Volume: 18
Issue: 8
Author(s): Mounir A. Salem, Mohamed S. Behalo and Rizk E. Khidre*
Affiliation:
- Chemistry Department, Faculty of Science, Jazan University, Jazan,Saudi Arabia
Keywords:
Triazolopyrimidine, pyrimidine, triazole, synthesis, heterocycles, pharmacological activities.
Abstract: This review deals with the synthetic methods, chemical reactions, and applications of triazolopyrimidine
derivatives. The synthetic methods and chemical reactions are subdivided into groups
according to the junction between triazole and pyrimidine moieties for instance [1,2,4]triazolo[1,5-
a]pyrimidine, [1,2,4]triazolo[1,5-c]pyrimidine, [1,2,3]triazolo[1,5-a]pyrimidine, [1,2,3]triazolo[1,5-
c]pyrimidine, [1,2,4]triazolo[4,3-c]pyrimidine, and [1,2,4]triazolo[4,3-a]pyrimidine. Pharmacological
activity of triazolopyrimidins is also reported.
