Title:A Short Review on the Synthesis of 1,2,4-Triazine Derivatives as Bioactive Compounds
Volume: 18
Issue: 8
Author(s): Heba E. Hashem*
Affiliation:
- Department of Chemistry, Faculty of Women, Ain Shams University, Heliopolis, Cairo 11757,Egypt
Keywords:
1, 2, 4-Triazine, fused triazine, heterocycles, biological activity, synthesis, oxo derivatives.
Abstract: Triazines and their oxo derivatives are a representative class of heterocyclic compounds
which have attracted great attention in organic synthesis and medicinal chemistry as they have been
associated with a broad range of pharmacological activities. 1,2,4-Triazines and their oxo derivatives
exhibit a broad range of biological activities, including antimicrobial, antifungal, anticancer, antiinflammatory,
besides having importance in the dyes and pesticides field. This review presents the
different methods of the synthesis of triazine/one derivatives. Also, this literature surveys the different
effects of these compounds in pharmaceuticals.