Title:Deciphering the Role of Nanoparticle-based Treatment for Parkinson’s Disease
Volume: 22
Issue: 7
Author(s): Md. Marufur Rahman Moni, Mst. Marium Begum, Md. Sahab Uddin*Ghulam Md Ashraf*
Affiliation:
- Department of Pharmacy, Southeast University, Dhaka,Bangladesh
- Pre-clinical Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah,Saudi Arabia
Keywords:
Parkinson's disease, progressive neurodegenerative disorder, nanotechnology, nanoparticles, α-synuclein, blood-brain barrier.
Abstract: Parkinson’s disease (PD) is a progressive neurodegenerative disorder that exerts a huge burden on
our society. The occurrence of this neurodegenerative disease has been increasing day-by-day. PD can be a serious
concern if the patients are left untreated. However, conventional treatment has many side-effects and less
bioavailability in the brain. Therefore, the necessary measurement is required to solve the limitations of PD
treatment. Nanotechnology has made a major contribution to comprehend PD pathogenesis. Nanotechnology
can provide efficient therapies that have reduced side-effects and increased bioavailability in the brain. This review
emphasizes the emerging promise of nanoparticle-based treatment, drug delivery, and other therapeutic approaches
for PD. Besides, the advantages of different approaches on nanotechnology platforms are far better
over conventional therapy in the treatment of PD.
