摘要
背景:世界范围内糖尿病发病率的上升促使研究人员从天然产品中探索新的抗糖尿病药物。关于糖尿病的伦理领域研究已经在全球扩展,记录了大量抗糖尿病的民间药用植物。尽管如此,迄今为止还没有对这些调查进行过系统的审查。这项研究记录了全球传统上用于管理糖尿病的药用植物。 方法:对科学直接、医学mebmed和谷歌学者等关键数据库进行了研究。植物列表和国际植物名称索引(IPNI)被用于验证科学的植物名称。 结果:2004年92个国家报告了1112属197科。主要报道豆科(105属193种)、菊科(97属188种)和羊科科(47属121种)。龙骨,龙骨,青葱属。法官。,金甘草(L.)。R.Br。前Sm.、芦荟(L.)Burm.f.和葱属植物的报道最多。事实上,实验研究已经证明了它们的抗糖尿病特性。几种通过不同机制作用的抗糖尿病化合物,包括莫莫苷、香霉苷、卡拉苷、葫芦素、香霉苷、香豆苷、s-烯丙基半胱氨酸亚砜 A. 讽刺,柠檬类从 A. 籼稻、生物碱包括长春碱、长春碱、长春碱和长春碱 C. 玫瑰酸、油苷和橙酸酸、黄酮c苷、异裂苷、裸子苷、裸子苷和妊娠糖苷 A. 维拉,和槲皮素来自 A. 有权杖。 结论:本文综述首次提供了世界范围内用来抗糖尿病的传统药用植物的汇编清单。
关键词: 糖尿病,民族医学、植物,传统医学,民族植物学、传统药用植物、c-糖苷、裸子植物苷类。
Current Medicinal Chemistry
Title:Ethnomedicinal Plants for the Management of Diabetes Worldwide: A Systematic Review
Volume: 28 Issue: 23
关键词: 糖尿病,民族医学、植物,传统医学,民族植物学、传统药用植物、c-糖苷、裸子植物苷类。
摘要:
Background: The increasing incidence of diabetes worldwide has urged researchers to explore novel antidiabetic agents from natural products. Ethnomedicinal field studies on diabetes have expanded across the globe, documenting large numbers of folk medicinal plants against diabetes. Nonetheless, a systematic review of these surveys has not been conducted so far. This study documents the medicinal plants traditionally used globally for managing diabetes.
Methods: Key databases including Sciencedirect, Medline/PubMed, and Google Scholar were scrutinized. The Plant List and The International Plant Names Index (IPNI) were used to validate the scientific plant names.
Results: 2004 traditionally used plants belonging to 1112 genera and 197 families were reported across 92 countries for the management of diabetes. Leguminosae (105 genera and 193 species), Compositae (97 genera and 188 species), and Lamiaceae (47 genera and 121 species) were the main plant families reported. Momordica charantia L., Syzygium cumini (L.) Skeels, Allium sativum L., Azadirachta indica A.Juss., Catharanthus roseus (L.) G.Don, Olea europaea L., Trigonella foenum-graecum L., Gymnema sylvestre (Retz.) R.Br. ex Sm., Aloe vera (L.) Burm.f., and Allium cepa L were the species mostly reported. Indeed, the antidiabetic properties of these main species have been evidenced by experimental studies. Several antidiabetic compounds acting via different mechanisms have been identified, including momordicoside, karaviloside, cucurbitacin, charantin, and charantoside from M. charantia, cuminoside from S. cumini, S-allyl cysteine sulfoxide from A. sativum, limonoids from A. indica, alkaloids including vindoline, vindolidine, vindolicine and vindolinine from C. roseus, oleuropein and oleanolic acid from O. europaea, flavone C-glycosides such as vicenin-1, isoschaftoside, and schaftoside from T. foenum-graecum seeds, gymnemosides, gymnemagenin, and pregnane glycosides from G. sylvestre, chysalodin from A. vera, and quercetin from A. cepa.
Conclusion: This review is the first to provide a compiled list of traditional medicinal plants used worldwide against diabetes.
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Cite this article as:
Ethnomedicinal Plants for the Management of Diabetes Worldwide: A Systematic Review, Current Medicinal Chemistry 2021; 28 (23) . https://dx.doi.org/10.2174/0929867328666210121123037
DOI https://dx.doi.org/10.2174/0929867328666210121123037 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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