Title:Biomimetic Drug Delivery Systems Oriented by Biological Function in Tumor Targeting
Volume: 22
Issue: 8
Author(s): Rui Wang and Xianyi Sha*
Affiliation:
- Key Laboratory of Smart Drug Delivery, Ministry of Education, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai,China
Keywords:
Biomimetic drug delivery system, Tumor targeting, Cell, Protein, Immunotherapy, Nanoparticle.
Abstract: The emergence of nanoscale drug delivery systems provides new opportunities for targeting
the delivery of chemotherapeutic drugs and has achieved excellent results. In recent years, with
the rise in the concept of intelligent drug delivery systems, the design and preparation of carriers
have become more and more complicated, which is not conducive to clinical transformation. Researchers
are gradually focused on biomimetic nanoscale drug delivery systems, trying to combine
the physicochemical properties of nanoscale carriers with the natural biological functions of endogenous
substances, so as to boost tumor targeting delivery. In this article, we first classify and introduce
biomimetic nanoscale drug delivery systems, and then emphasize their unique biological
functions. The biomimetic nanoscale drug delivery systems have the advantages of simple preparation,
powerful functions, and low immunogenicity, having a good application prospect.