Title:Relationship between Hyperlipidemia, Cardiovascular Disease and Stroke: A Systematic Review
Volume: 17
Issue: 6
Author(s): Aladeen Alloubani*, Refat Nimer and Rama Samara
Affiliation:
- Nursing Research Unit, King Hussein Cancer Center, Amman, Jordan
Keywords:
Hyperlipidemia, stroke, cardiovascular disease, risk factors, dyslipidemia, cardiovascular and cerebrovascular events.
Abstract:
Background: Globally, dyslipidemia has been shown to be an independent predictor of
many cardiovascular and cerebrovascular events, which led to recent advocacy towards dyslipidemia
prevention and control as a key risk factor and its prognostic significance to reduce the burden
of stroke and myocardial infarction (MI).
Aims: This study aimed to evaluate hyperlipidemia as a risk factor connected with stroke and
CVD. Moreover, having identified this risk factor, the study evaluates how hyperlipidemia has
been examined earlier and what can be done in the future.
Methods: All prospective studies concerning hyperlipidemia as risk factors for stroke and CVD
were identified by a search of PubMed/MEDLINE and EMBASE databases with keywords hyperlipidemia,
risk factors, stroke, and cardiovascular disease.
Results: The constant positive association between the incidence of coronary heart disease and
cholesterol concentration of LDL is apparent in observational studies in different populations.
Thus, the reduction of LDL cholesterol in those populations, particularly with regard to initial
cholesterol concentrations, can reduce the risk of vascular diseases. However, the impact of using
lipid-lowering drugs, such as statins, has been demonstrated in several studies as an important factor
in decreasing the mortality and morbidity rates of patients with stroke and CVD.
Conclusion: After reviewing all the research mentioned in this review, most studies confirmed that
hyperlipidemia is a risk factor for stroke and correlated in patients with CVD.
