一个小综述：胞外囊泡在肿瘤诊断中的应用

Title:Extracellular Vesicles in Tumor Diagnosis: A Mini-Review

Volume: 21 Issue: 7

关键词: 细胞外囊泡，癌症诊断，生物标志物，外泌体，肿瘤微环境，微囊泡。

摘要: Wide exploration of noninvasive tumor/cancer biomarkers has shed light on clinical diagnosis. However, many under-investigated biomarkers showed limited application potency due to low sensitivity and specificity, while extracellular vehicles (EVs) were gradually recognized as promising candidates. EVs are small vesicles transporting bioactive cargos between cells in multiple physiological processes and also in tumor/cancer pathogenesis. This review aimed to offer recent studies of EVs on structure, classification, physiological functions, as well as changes in tumor initiation and progression. Furthermore, we focused on advances of EVs and/or EV-related substances in cancer diagnosis, and summarized ongoing studies of promising candidates for future investigations.

Cite this article as:

Extracellular Vesicles in Tumor Diagnosis: A Mini-Review, Current Molecular Medicine 2021; 21 (7) . https://dx.doi.org/10.2174/1573405616666201209103154