摘要
皮肤癌仍然是全世界死亡率的主要原因。 它可以分为黑色素瘤和非黑色素瘤,主要包括鳞状细胞癌和基底细胞癌。 尽管常规疗法改善了皮肤癌的治疗,但是寻找化学预防化合物仍然是治疗癌症的最有效和最安全的策略。 如今,化学预防被认为是使用天然产物预防或抑制致癌步骤的一种新颖方法。 植物粗提取物和分离的植物化合物被认为是化学预防剂,因为它们具有抗炎,抗氧化和抗癌的特性,可抗多种类型的疾病和癌症。 在这篇综述中,我们将讨论用作粗提物或植物化合物的精选药用植物对黑素瘤和非黑素瘤皮肤癌的治疗效果和预防潜力。
关键词: 皮肤癌,植物化合物,天然产物,化学预防,黑色素瘤,癌症。
Current Drug Targets
Title:Medicinal Plants Towards Modeling Skin Cancer
Volume: 22 Issue: 2
关键词: 皮肤癌,植物化合物,天然产物,化学预防,黑色素瘤,癌症。
摘要: Skin cancer remains a major cause of mortality worldwide. It can be divided into melanoma and non-melanoma cancer, which comprise mainly squamous cell carcinoma and basal cell carcinoma. Although conventional therapies have ameliorated the management of skin cancer, the search for chemopreventive compounds is still the most effective and safer strategy to treat cancer. Nowadays, chemoprevention is recognized as a novel approach to prevent or inhibit carcinogenesis steps with the use of natural products. Crude extracts of plants and isolated phytocompounds are considered chemopreventive agents since they harbor anti-inflammatory, antioxidant and anti-oncogenic properties against many types of diseases and cancers. In this review, we will discuss the therapeutic effect and preventive potential of selected medicinal plants used as crude extracts or as phytocompounds against melanoma and non-melanoma cutaneous cancers.
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Cite this article as:
Medicinal Plants Towards Modeling Skin Cancer, Current Drug Targets 2021; 22 (2) . https://dx.doi.org/10.2174/1389450121666201005103521
DOI https://dx.doi.org/10.2174/1389450121666201005103521 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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