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Review Article

纤维母细胞生长因子:治疗精神分裂症的理想目标

卷 21, 期 13, 2020

页: [1344 - 1353] 页: 10

弟呕挨: 10.2174/1389450121666200628114843

价格: $65

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摘要

精神分裂症是世界上最严重的精神疾病之一。它的特征是神经解剖或生化变化。近年来，成纤维细胞生长因子(FGFs)系统在精神分裂症中的作用受到了广泛关注。基因表达和/或FGFs水平的各种变化与精神分裂症的病因、症状和进展有关。例如，研究证实了FGFs与多巴胺受体信号通路之间的相互作用。为了了解该系统在精神分裂症中的作用，我们搜索了开放存取期刊数据库、Web of Science、PubMed (NLM)、LISTA (EBSCO)和谷歌学术，其中的关键词包括纤维母细胞生长因子、多巴胺、精神分裂症、精神病以及神经营养。综上所述，FGF家族代表了精神分裂症新的药物靶点和治疗靶点的候选分子。

关键词: 纤维母细胞生长因子，多巴胺，精神分裂症，精神病，神经营养，抗精神病药物。

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