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当代阿耳茨海默病研究

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Systematic Review Article

系统综述：阿尔茨海默病社会认知与执行功能的关系

卷 17, 期 5, 2020

页: [487 - 497] 页: 11

弟呕挨: 10.2174/1567205017666200626205154

价格: $65

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摘要

简介:社会认知（SC）是一个复杂的概念，它反映了一系列的内隐和外显的认知过程。许多神经认知领域与SC相关，执行功能(EF)是其中最具代表性的一个。我们进行了一项系统的综述，旨在阐明在阿尔茨海默病(AD)患者中，SC损伤是否与EF功能障碍相关。 方法:在2007年1月至2019年12月期间，使用Pubmed、SciELO、BIREME和Thomson Reuters科学网络电子数据库，基于系统综述和综合分析的首选报告项目(PRISMA)进行检索。关键词为SC、AD、EF、神经心理功能和执行障碍。 结果:共鉴定136篇，纳入15篇。这些研究对AD中SC缺失的程度不一致，主要是在该病的轻度阶段。EF缺陷，特别是抑制和操纵语言信息的能力，与AD的SC损伤相关。SC随疾病进展而下降，这一关系可以解释为整体认知障碍和SC特异性症状。 结论:SC损伤与疾病进展有关，主要是由于EF下降所致。对SC成分的研究是不平等的，导致了心理理论结果的频繁泛化，并经常妨碍对其他成分的研究，主要是同理心。更准确地了解SC在AD中的作用可能有助于更好地理解行为变化和人际互动。

关键词: 心智理论，情感识别，共情，认知，执行功能，阿尔茨海默病。

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