Abstract
Nitric oxide (NO) possesses many physiological effects and S-nitrosothiols have been identified in a variety of tissues exhibiting many NO-like activities. This review focuses on the latest discoveries pertaining to the biological functions of S-nitrosothiols and the recent research progress in the chemical properties and biomedical applications of RSNOs.
Keywords: S nitrosothiols, nitric oxide NO, RSNOs, superoxide catalzed RSNO, blood flow regulation, apotosis, platelet neutrophil interaactions, perinatal circulatory transition, S Nitroso 1 thiolsugars, TGSNO, S nitrosopeptides, Drug SNO conjugates, adrenergic receptor, Cu Zn superoxide dismutase, cardiac calcium release channel, cyclic nucleotide gated channel, interleukin converting enzyme, inducible nitric oxide synthase, xanthine oxidase, s Nitrosohemoglobin, disulfide, s Nitrosothiol, thiyl radical, glucopyranose
Current Medicinal Chemistry
Title: New Chemical and Biological Aspects of S-Nitrosothiols
Volume: 7 Issue: 8
Author(s): K. Wang, W. Zhang, M. Xian, Y. C. Hou, X. C Chen, J. P. Cheng and P. G. Wang
Affiliation:
Keywords: S nitrosothiols, nitric oxide NO, RSNOs, superoxide catalzed RSNO, blood flow regulation, apotosis, platelet neutrophil interaactions, perinatal circulatory transition, S Nitroso 1 thiolsugars, TGSNO, S nitrosopeptides, Drug SNO conjugates, adrenergic receptor, Cu Zn superoxide dismutase, cardiac calcium release channel, cyclic nucleotide gated channel, interleukin converting enzyme, inducible nitric oxide synthase, xanthine oxidase, s Nitrosohemoglobin, disulfide, s Nitrosothiol, thiyl radical, glucopyranose
Abstract: Nitric oxide (NO) possesses many physiological effects and S-nitrosothiols have been identified in a variety of tissues exhibiting many NO-like activities. This review focuses on the latest discoveries pertaining to the biological functions of S-nitrosothiols and the recent research progress in the chemical properties and biomedical applications of RSNOs.
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Cite this article as:
Wang K., Zhang W., Xian M., Hou C. Y., Chen C X., Cheng P. J. and Wang G. P., New Chemical and Biological Aspects of S-Nitrosothiols, Current Medicinal Chemistry 2000; 7 (8) . https://dx.doi.org/10.2174/0929867003374633
DOI https://dx.doi.org/10.2174/0929867003374633 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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