Nanomaterials-based Cell Osteogenic Differentiation and Bone Regeneration

Tianxu       Zhang; Yang       Gao; Weitong       Cui; Yanjing       Li; Dexuan       Xiao; Ronghui       Zhou
doi:10.2174/1574888X15666200521083834
Abstract

With the rapid development of nanotechnology, various nanomaterials have been applied to bone repair and regeneration. Due to the unique chemical, physical and mechanical properties, nanomaterials could promote stem cells osteogenic differentiation, which has great potentials in bone tissue engineering and exploiting nanomaterials-based bone regeneration strategies. In this review, we summarized current nanomaterials with osteo-induction ability, which could be potentially applied to bone tissue engineering. Meanwhile, the unique properties of these nanomaterials and their effects on stem cell osteogenic differentiation are also discussed. Furthermore, possible signaling pathways involved in the nanomaterials- induced cell osteogenic differentiation are also highlighted in this review.
Keywords: Nanomaterials, stem cells, osteogenic differentiation, bone regeneration, oste-induction, nanotechnology.
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DOI https://dx.doi.org/10.2174/1574888X15666200521083834	Print ISSN 1574-888X
Publisher Name Bentham Science Publisher	Online ISSN 2212-3946
Current Stem Cell Research & Therapy

Nanomaterials-based Cell Osteogenic Differentiation and Bone Regeneration

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