Radiopharmaceuticals for the Visualization of Infectious and Inflammatory Lesions

Title: Radiopharmaceuticals for the Visualization of Infectious and Inflammatory Lesions

Volume: 6 Issue: 11

Author(s): Meral Tayan Ercan and Lale Kostakoglu

Affiliation:

Abstract: Many radiopharmaceuticals have been introduced for the scintigraphic demonstration of infectious and inflammatory lesions and some of them are currently in clinical use. They can be classified into two major categories according to their specificity. Specific radiopharmaceuticals include in vitro labeled leukocytes, radiolabelled monoclonal antibodies, and receptor specific small proteins and peptides. Nonspecific radiopharmaceuticals include radiolabelled nanocolloids, liposomes, macromolecules such as human immunoglobulin, dextran and human serum albumin, various small molecules and ions. In this review article radiopharmaceuticals in their respective groups are discussed as to the efficacy, and other parameters such as the physical characteristics of the radionuclides used, radiochemistry involved, availability, cost and biodistribution, emphasizing recent developments.

Cite this article as:

Tayan Ercan Meral and Kostakoglu Lale, Radiopharmaceuticals for the Visualization of Infectious and Inflammatory Lesions, Current Pharmaceutical Design 2000; 6 (11) . https://dx.doi.org/10.2174/1381612003399914