Login Register Cart 0
Generic placeholder image

Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Review Article

Marine Actinomycetes-derived Natural Products

Author(s): Chengfang Yang, Rui Qian, Yao Xu, Junxi Yi, Yiwen Gu, Xiaoyu Liu, Haobing Yu, Binghua Jiao, Xiaoling Lu* and Wei Zhang*

Volume 19, Issue 31, 2019

Page: [2868 - 2918] Pages: 51

DOI: 10.2174/1568026619666191114102359

Price: $65

Abstract

Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities.

Keywords: Marine actinomycetes, Secondary metabolites, Antibacterial activity, Antiviral activity, Cytotoxic activity, Lead compound.

« Previous Next »
Graphical Abstract

[1]
Blunt, J.W.; Copp, B.R.; Keyzers, R.A.; Munro, M.H.G.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2014, 31(2), 160-258.
[http://dx.doi.org/10.1039/c3np70117d] [PMID: 24389707]
[2]
Blunt, J.W.; Copp, B.R.; Keyzers, R.A.; Munro, M.H.G.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2017, 34(3), 235-294.
[http://dx.doi.org/10.1039/C6NP00124F] [PMID: 28290569]
[3]
Blunt, J.W.; Copp, B.R.; Keyzers, R.A.; Munro, M.H.G.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2016, 33(3), 382-431.
[http://dx.doi.org/10.1039/C5NP00156K] [PMID: 26837534]
[4]
Blunt, J.W.; Copp, B.R.; Keyzers, R.A.; Munro, M.H.G.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2015, 32(2), 116-211.
[http://dx.doi.org/10.1039/C4NP00144C] [PMID: 25620233]
[5]
Barka, E.A.; Vatsa, P.; Sanchez, L.; Gaveau-Vaillant, N.; Jacquard, C.; Meier-Kolthoff, J.P.; Klenk, H.P.; Clément, C.; Ouhdouch, Y.; van Wezel, G.P. Taxonomy, physiology, and natural products of actinobacteria. Microbiol. Mol. Biol. Rev., 2015, 80(1), 1-43.
[http://dx.doi.org/10.1128/MMBR.00019-15] [PMID: 26609051]
[6]
Manivasagan, P.; Venkatesan, J.; Sivakumar, K.; Kim, S-K. Pharmaceutically active secondary metabolites of marine actinobacteria. Microbiol. Res., 2014, 169(4), 262-278.
[http://dx.doi.org/10.1016/j.micres.2013.07.014] [PMID: 23958059]
[7]
Jensen, P.R.; Moore, B.S.; Fenical, W. The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery. Nat. Prod. Rep., 2015, 32(5), 738-751.
[http://dx.doi.org/10.1039/C4NP00167B] [PMID: 25730728]
[8]
Soldatou, S.; Baker, B.J. Cold-water marine natural products, 2006 to 2016. Nat. Prod. Rep., 2017, 34(6), 585-626.
[http://dx.doi.org/10.1039/C6NP00127K] [PMID: 28322384]
[9]
Abdelmohsen, U.R.; Bayer, K.; Hentschel, U. Diversity, abundance and natural products of marine sponge-associated actinomycetes. Nat. Prod. Rep., 2014, 31(3), 381-399.
[http://dx.doi.org/10.1039/C3NP70111E] [PMID: 24496105]
[10]
Li, G.; Kusari, S.; Spiteller, M. Natural products containing ‘decalin’ motif in microorganisms. Nat. Prod. Rep., 2014, 31(9), 1175-1201.
[http://dx.doi.org/10.1039/C4NP00031E] [PMID: 24984916]
[11]
Cai, W.; Wang, X.; Elshahawi, S.I.; Ponomareva, L.V.; Liu, X.; McErlean, M.R.; Cui, Z.; Arlinghaus, A.L.; Thorson, J.S.; Van Lanen, S.G. Antibacterial and Cytotoxic Actinomycins Y6-Y9 and Zp from Streptomyces sp. Strain Gö-GS12. J. Nat. Prod., 2016, 79(10), 2731-2739.
[http://dx.doi.org/10.1021/acs.jnatprod.6b00742] [PMID: 27736087]
[12]
Sreedharan, V.; Bhaskara Rao, K.V. Efficacy of protease inhibitor from marine Streptomyces sp. VITBVK2 against Leishmania donovani - An in vitro study. Exp. Parasitol., 2017, 174, 45-51.
[http://dx.doi.org/10.1016/j.exppara.2017.02.007] [PMID: 28167209]
[13]
Younis, K.M.; Usup, G.; Ahmad, A. Secondary metabolites produced by marine streptomyces as antibiofilm and quorum-sensing inhibitor of uropathogen Proteus mirabilis. Environ. Sci. Pollut. Res. Int., 2016, 23(5), 4756-4767.
[http://dx.doi.org/10.1007/s11356-015-5687-9] [PMID: 26538254]
[14]
Yang, N.; Sun, C. The Inhibition and Resistance Mechanisms of Actinonin, Isolated from Marine Streptomyces sp. NHF165, against Vibrio anguillarum. Front. Microbiol., 2016, 7, 1467.
[http://dx.doi.org/10.3389/fmicb.2016.01467] [PMID: 27679625]
[15]
Elmallah, M.I.Y.; Micheau, O.; Eid, M.A.G.; Hebishy, A.M.S.; Abdelfattah, M.S. Marine actinomycete crude extracts with potent TRAIL-resistance overcoming activity against breast cancer cells. Oncol. Rep., 2017, 37(6), 3635-3642.
[http://dx.doi.org/10.3892/or.2017.5595] [PMID: 28440502]
[16]
Bérdy, J. Bioactive microbial metabolites. J. Antibiot. (Tokyo), 2005, 58(1), 1-26.
[http://dx.doi.org/10.1038/ja.2005.1] [PMID: 15813176]
[17]
Ma, L.; Bartholome, A.; Tong, M.H.; Qin, Z.; Yu, Y.; Shepherd, T.; Kyeremeh, K.; Deng, H.; O’Hagan, D. Identification of a fluorometabolite from Streptomyces sp. MA37: (2R3S4S)-5-fluoro-2,3,4-trihydroxypentanoic acid. Chem. Sci. (Camb.), 2015, 6(2), 1414-1419.
[http://dx.doi.org/10.1039/C4SC03540B] [PMID: 29861965]
[18]
Ramalingam, V.; Rajaram, R. Antioxidant activity of 1-hydroxy-1-norresistomycin derived from Streptomyces variabilis KP149559 and evaluation of its toxicity against zebra fish Danio rerio. RSC Advances, 2016, 6(20), 16615-16623.
[http://dx.doi.org/10.1039/C5RA22558B]
[19]
Dickschat, J.S. Bacterial terpene cyclases. Nat. Prod. Rep., 2016, 33(1), 87-110.
[http://dx.doi.org/10.1039/C5NP00102A] [PMID: 26563452]
[20]
Romero, C.A.; Grkovic, T.; Han, J.; Zhang, L.; French, J.R.J.; Kurtböke, D.I.; Quinn, R.J. NMR fingerprints, an integrated approach to uncover the unique components of the drug-like natural product metabolome of termite gut-associated Streptomyces species. RSC Advances, 2015, 5(126), 104524-104534.
[http://dx.doi.org/10.1039/C5RA17553D]
[21]
Lian, X.Y.; Zhang, Z. Indanomycin-related antibiotics from marine Streptomyces antibioticus PTZ0016. Nat. Prod. Res., 2013, 27(23), 2161-2167.
[http://dx.doi.org/10.1080/14786419.2013.793688] [PMID: 23639115]
[22]
Song, Y.; Huang, H.; Chen, Y.; Ding, J.; Zhang, Y.; Sun, A.; Zhang, W.; Ju, J. Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406. J. Nat. Prod., 2013, 76(12), 2263-2268.
[http://dx.doi.org/10.1021/np4006025] [PMID: 24251399]
[23]
Chen, C.; Wang, J.; Guo, H.; Hou, W.; Yang, N.; Ren, B.; Liu, M.; Dai, H.; Liu, X.; Song, F.; Zhang, L. Three antimycobacterial metabolites identified from a marine-derived Streptomyces sp. MS100061. Appl. Microbiol. Biotechnol., 2013, 97(9), 3885-3892.
[http://dx.doi.org/10.1007/s00253-012-4681-0] [PMID: 23324803]
[24]
Pan, H.Q.; Zhang, S.Y.; Wang, N.; Li, Z.L.; Hua, H.M.; Hu, J.C.; Wang, S.J. New spirotetronate antibiotics, lobophorins H and I, from a South China Sea-derived Streptomyces sp. 12A35. Mar. Drugs, 2013, 11(10), 3891-3901.
[http://dx.doi.org/10.3390/md11103891] [PMID: 24132178]
[25]
Wu, Z.; Li, S.; Li, J.; Chen, Y.; Saurav, K.; Zhang, Q.; Zhang, H.; Zhang, W.; Zhang, W.; Zhang, S.; Zhang, C. Antibacterial and cytotoxic new napyradiomycins from the marine-derived Streptomyces sp. SCSIO 10428. Mar. Drugs, 2013, 11(6), 2113-2125.
[http://dx.doi.org/10.3390/md11062113] [PMID: 23771045]
[26]
Um, S.; Choi, T.J.; Kim, H.; Kim, B.Y.; Kim, S.H.; Lee, S.K.; Oh, K.B.; Shin, J.; Oh, D.C. Ohmyungsamycins A and B: cytotoxic and antimicrobial cyclic peptides produced by Streptomyces sp. from a volcanic island. J. Org. Chem., 2013, 78(24), 12321-12329.
[http://dx.doi.org/10.1021/jo401974g] [PMID: 24266328]
[27]
Bae, M.; Kim, H.; Shin, Y.; Kim, B.Y.; Lee, S.K.; Oh, K.B.; Shin, J.; Oh, D.C.; Separacenes, A-D. Separacenes A-D, novel polyene polyols from the marine actinomycete, Streptomyces sp. Mar. Drugs, 2013, 11(8), 2882-2893.
[http://dx.doi.org/10.3390/md11082882] [PMID: 23945600]
[28]
Sung, A.A.; Gromek, S.M.; Balunas, M.J. Upregulation and identification of antibiotic activity of a marine-derived Streptomyces sp. via co-cultures with human pathogens. Mar. Drugs, 2017, 15(8)E250
[http://dx.doi.org/10.3390/md15080250] [PMID: 28800088]
[29]
Wu, C.; Tan, Y.; Gan, M.; Wang, Y.; Guan, Y.; Hu, X.; Zhou, H.; Shang, X.; You, X.; Yang, Z.; Xiao, C. Identification of elaiophylin derivatives from the marine-derived actinomycete Streptomyces sp. 7-145 using PCR-based screening. J. Nat. Prod., 2013, 76(11), 2153-2157.
[http://dx.doi.org/10.1021/np4006794] [PMID: 24164206]
[30]
Akhter, N.; Liu, Y.; Auckloo, B.N.; Shi, Y.; Wang, K.; Chen, J.; Wu, X.; Wu, B. Stress-driven discovery of new angucycline-type antibiotics from a marine streptomyces pratensis NA-ZhouS1. Mar. Drugs, 2018, 16(9)E331
[http://dx.doi.org/10.3390/md16090331] [PMID: 30213076]
[31]
Liang, Y.; Chen, L.; Ye, X.; Anjum, K.; Lian, X.Y.; Zhang, Z. New streptophenazines from marine Streptomyces sp. 182SMLY. Nat. Prod. Res., 2017, 31(4), 411-417.
[http://dx.doi.org/10.1080/14786419.2016.1169419] [PMID: 27097765]
[32]
Zhang, F.; Adnani, N.; Vazquez-Rivera, E.; Braun, D.R.; Tonelli, M.; Andes, D.R.; Bugni, T.S. Application of 3D NMR for structure determination of peptide natural products. J. Org. Chem., 2015, 80(17), 8713-8719.
[http://dx.doi.org/10.1021/acs.joc.5b01486] [PMID: 26273993]
[33]
Yang, X.W.; Zhang, G.Y.; Ying, J.X.; Yang, B.; Zhou, X.F.; Steinmetz, A.; Liu, Y.H.; Wang, N. Isolation, characterization, and bioactivity evaluation of 3-((6-methylpyrazin-2-yl)methyl)-1H-indole, a new alkaloid from a deep-sea-derived actinomycete Serinicoccus profundi sp. nov. Mar. Drugs, 2012, 11(1), 33-39.
[http://dx.doi.org/10.3390/md11010033] [PMID: 23271423]
[34]
Liu, N.; Shang, F.; Xi, L.; Huang, Y. Tetroazolemycins A and B, two new oxazole-thiazole siderophores from deep-sea Streptomyces olivaceus FXJ8.012. Mar. Drugs, 2013, 11(5), 1524-1533.
[http://dx.doi.org/10.3390/md11051524] [PMID: 23665958]
[35]
Djinni, I.; Defant, A.; Kecha, M.; Mancini, I. Antibacterial polyketides from the marine alga-derived endophitic Streptomyces sundarbansensis: a study on hydroxypyrone tautomerism. Mar. Drugs, 2013, 11(1), 124-135.
[http://dx.doi.org/10.3390/md11010124] [PMID: 23306172]
[36]
Huang, H.; Cao, Y.; Tian, L.; Lin, W.; Zhang, K. A new polyunsaturated acid from the marine-derived streptomyces violans (No. HTTA-F04129). Chem. Nat. Compd., 2014, 50(3), 402-404.
[37]
Kunz, A.L.; Labes, A.; Wiese, J.; Bruhn, T.; Bringmann, G.; Imhoff, J.F. Nature’s lab for derivatization: new and revised structures of a variety of streptophenazines produced by a sponge-derived Streptomyces strain. Mar. Drugs, 2014, 12(4), 1699-1714.
[http://dx.doi.org/10.3390/md12041699] [PMID: 24670532]
[38]
Zhen, X.; Gong, T.; Liu, F.; Zhang, P.C.; Zhou, W.Q.; Li, Y.; Zhu, P. A new analogue of echinomycin and a new cyclic dipeptide from a marine-derived streptomyces sp. LS298. Mar. Drugs, 2015, 13(11), 6947-6961.
[http://dx.doi.org/10.3390/md13116947] [PMID: 26593927]
[39]
Braña, A.F.; Sarmiento-Vizcaíno, A.; Pérez-Victoria, I.; Otero, L.; Fernández, J.; Palacios, J.J.; Martín, J.; de la Cruz, M.; Díaz, C.; Vicente, F.; Reyes, F.; García, L.A.; Blanco, G. Branimycins B and C, Antibiotics produced by the abyssal actinobacterium pseudonocardia carboxydivorans m-227. J. Nat. Prod., 2017, 80(2), 569-573.
[http://dx.doi.org/10.1021/acs.jnatprod.6b01107] [PMID: 28169531]
[40]
Wyche, T.P.; Alvarenga, R.F.R.; Piotrowski, J.S.; Duster, M.N.; Warrack, S.R.; Cornilescu, G.; De Wolfe, T.J.; Hou, Y.; Braun, D.R.; Ellis, G.A.; Simpkins, S.W.; Nelson, J.; Myers, C.L.; Steele, J.; Mori, H.; Safdar, N.; Markley, J.L.; Rajski, S.R.; Bugni, T.S. Chemical genomics, structure elucidation, and in vivo studies of the marine-derived anticlostridial ecteinamycin. ACS Chem. Biol., 2017, 12(9), 2287-2295.
[http://dx.doi.org/10.1021/acschembio.7b00388] [PMID: 28708379]
[41]
Takehana, Y.; Umekita, M.; Hatano, M.; Kato, C.; Sawa, R.; Igarashi, M.; Fradiamine, A. Fradiamine A, a new siderophore from the deep-sea actinomycete Streptomyces fradiae MM456M-mF7. J. Antibiot. (Tokyo), 2017, 70(5), 611-615.
[http://dx.doi.org/10.1038/ja.2017.26] [PMID: 28246378]
[42]
Wang, Q.; Zhang, Y.; Wang, M.; Tan, Y.; Hu, X.; He, H.; Xiao, C.; You, X.; Wang, Y.; Gan, M. Neo-actinomycins A and B, natural actinomycins bearing the 5H-oxazolo[4,5-b]phenoxazine chromophore, from the marine-derived Streptomyces sp. IMB094. Sci. Rep., 2017, 7(1), 3591.
[http://dx.doi.org/10.1038/s41598-017-03769-8] [PMID: 28620204]
[43]
Hu, Y.; Wang, M.; Wu, C.; Tan, Y.; Li, J.; Hao, X.; Duan, Y.; Guan, Y.; Shang, X.; Wang, Y.; Xiao, C.; Gan, M. Identification and proposed relative and absolute configurations of niphimycins c-e from the marine-derived streptomyces sp. IMB7-145 by genomic analysis. J. Nat. Prod., 2018, 81(1), 178-187.
[http://dx.doi.org/10.1021/acs.jnatprod.7b00859] [PMID: 29308897]
[44]
Iniyan, A.M.; Sudarman, E.; Wink, J.; Kannan, R.R.; Vincent, S.G.P. Ala-geninthiocin, a new broad spectrum thiopeptide antibiotic, produced by a marine Streptomyces sp. ICN19. J. Antibiot. (Tokyo), 2019, 72(2), 99-105.
[http://dx.doi.org/10.1038/s41429-018-0115-2] [PMID: 30356080]
[45]
Xu, D.; Nepal, K.K.; Chen, J.; Harmody, D.; Zhu, H.; McCarthy, P.J.; Wright, A.E.; Wang, G.; Nocardiopsistins, A-C. Nocardiopsistins A-C: New angucyclines with anti-MRSA activity isolated from a marine sponge-derived Nocardiopsis sp. HB-J378. Synth Syst Biotechnol, 2018, 3(4), 246-251.
[http://dx.doi.org/10.1016/j.synbio.2018.10.008] [PMID: 30417139]
[46]
Arai, M.; Kamiya, K.; Pruksakorn, P.; Sumii, Y.; Kotoku, N.; Joubert, J.P.; Moodley, P.; Han, C.; Shin, D.; Kobayashi, M. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorg. Med. Chem., 2015, 23(13), 3534-3541.
[http://dx.doi.org/10.1016/j.bmc.2015.04.033] [PMID: 25934225]
[47]
Dashti, Y.; Grkovic, T.; Abdelmohsen, U.R.; Hentschel, U.; Quinn, R.J. Production of induced secondary metabolites by a co-culture of sponge-associated actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163. Mar. Drugs, 2014, 12(5), 3046-3059.
[http://dx.doi.org/10.3390/md12053046] [PMID: 24857962]
[48]
Ko, K.; Lee, S.H.; Kim, S.H.; Kim, E.H.; Oh, K.B.; Shin, J.; Oh, D.C. Lajollamycins, nitro group-bearing spiro-β-lactone-γ-lactams obtained from a marine-derived Streptomyces sp. J. Nat. Prod., 2014, 77(9), 2099-2104.
[http://dx.doi.org/10.1021/np500500t] [PMID: 25211234]
[49]
Choi, E.J.; Nam, S.J.; Paul, L.; Beatty, D.; Kauffman, C.A.; Jensen, P.R.; Fenical, W. Previously uncultured marine bacteria linked to novel alkaloid production. Chem. Biol., 2015, 22(9), 1270-1279.
[http://dx.doi.org/10.1016/j.chembiol.2015.07.014] [PMID: 26299672]
[50]
Zhang, D.; Shu, C.; Lian, X.; Zhang, Z. New antibacterial bagremycins F and G from the marine-derived streptomyces sp. ZZ745. Mar. Drugs, 2018, 16(9)E330
[http://dx.doi.org/10.3390/md16090330] [PMID: 30213054]
[51]
Cao, D.T.; Tran, V.H.; Vu, V.N.; Mai, H.D.T.; Le, T.H.M.; Vu, T.Q.; Nguyen, H.H.; Chau, V.M.; Pham, V.C. Antimicrobial metabolites from a marine-derived Actinomycete Streptomyces sp. Nat. Prod. Res., 2018, G278. 33(22), 1-8.
[PMID: 29726708]
[52]
Cong, Z.; Huang, X.; Liu, Y.; Liu, Y.; Wang, P.; Liao, S.; Yang, B.; Zhou, X.; Huang, D.; Wang, J. Cytotoxic anthracycline and antibacterial tirandamycin analogues from a marine-derived Streptomyces sp. SCSIO 41399. J. Antibiot. (Tokyo), 2019, 72(1), 45-49.
[http://dx.doi.org/10.1038/s41429-018-0103-6] [PMID: 30258222]
[53]
Chen, S.; Zhang, D.; Chen, M.; Zhang, Z.; Lian, X.Y. A rare diketopiperazine glycoside from marine-sourced Streptomyces sp. ZZ446. Nat. Prod. Res., 2018, 1-5.
[http://dx.doi.org/10.1080/14786419.2018.1544978] [PMID: 30580590]
[54]
Hamed, A.; Abdel-Razek, A.S.; Frese, M.; Wibberg, D.; El-Haddad, A.F.; Ibrahim, T.M.A.; Kalinowski, J.; Sewald, N.; Shaaban, M. N-Acetylborrelidin B: a new bioactive metabolite from Streptomyces mutabilis sp. MII. Z. Natforsch. C J. Biosci., 2018, 73(1-2), 49-57.
[http://dx.doi.org/10.1515/znc-2017-0140] [PMID: 29055178]
[55]
Rodríguez, V.; Martín, J.; Sarmiento-Vizcaíno, A.; de la Cruz, M.; García, L.A.; Blanco, G.; Reyes, F.; Anthracimycin, B. Anthracimycin B, a potent antibiotic against gram-positive bacteria isolated from cultures of the deep-sea Actinomycete Streptomyces cyaneofuscatus M-169. Mar. Drugs, 2018, 16(11)E406
[http://dx.doi.org/10.3390/md16110406] [PMID: 30366404]
[56]
Cao, D.D.; Do, T.Q.; Doan Thi Mai, H.; Vu Thi, Q.; Nguyen, M.A.; Le Thi, H.M.; Tran, D.T.; Chau, V.M. Cong Thung, D.; Pham, V.C. Antimicrobial lavandulylated flavonoids from a sponge-derived actinomycete. Nat. Prod. Res., 2018, 1-8.
[57]
Leutou, A.S.; Yang, I.; Le, T.C.; Hahn, D.; Lim, K.M.; Nam, S.J.; Fenical, W. Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis. J. Antibiot. (Tokyo), 2018, 71(6), 609-612.
[http://dx.doi.org/10.1038/s41429-018-0033-3] [PMID: 29467379]
[58]
Gong, T.; Zhen, X.; Li, X.L.; Chen, J.J.; Chen, T.J.; Yang, J.L.; Zhu, P.; Tetrocarcin, Q. Tetrocarcin Q, a new spirotetronate with a unique glycosyl group from a marine-derived actinomycete micromonospora carbonacea LS276. Mar. Drugs, 2018, 16(2)E74
[http://dx.doi.org/10.3390/md16020074] [PMID: 29495293]
[59]
Pérez-Bonilla, M.; Oves-Costales, D.; de la Cruz, M.; Kokkini, M.; Martín, J.; Vicente, F.; Genilloud, O.; Reyes, F. Phocoenamicins B and C, new antibacterial spirotetronates isolated from a marine Micromonospora sp. Mar. Drugs, 2018, 16(3)E95
[http://dx.doi.org/ 10.3390/md16030095] [PMID: 29547589]
[60]
Chen, M.H.; Zhang, W.L.; Chen, L.; Lin, R.; Xie, Y.; Fang, D.S.; Lian, Y.Y.; Jiang, H. Isolation, purification and identification of two new alkaloids metabolites from marine-derived Verrucosispora sp. Nat. Prod. Res. , 2018, FIM06025. 33(20), 1-7.
[PMID: 30445864]
[61]
Pesic, A.; Baumann, H.I.; Kleinschmidt, K.; Ensle, P.; Wiese, J.; Süssmuth, R.D.; Imhoff, J.F. Champacyclin, a new cyclic octapeptide from Streptomyces strain C42 isolated from the Baltic Sea. Mar. Drugs, 2013, 11(12), 4834-4857.
[http://dx.doi.org/10.3390/md11124834] [PMID: 24317473]
[62]
Yang, C.L.; Wang, Y.S.; Liu, C.L.; Zeng, Y.J.; Cheng, P.; Jiao, R.H.; Bao, S.X.; Huang, H.Q.; Tan, R.X.; Ge, H.M. Strepchazolins A and B: Two New Alkaloids from a Marine Streptomyces chartreusis NA02069. Mar. Drugs, 2017, 15(8)E244
[http://dx.doi.org/10.3390/md15080244] [PMID: 28767052]
[63]
Guo, Z.K.; Wang, R.; Chen, S.Q.; Chen, F.X.; Liu, T.M.; Yang, M.Q.; Anthocidins, A. (-)D, New 5-hydroxyanthranilic acid related metabolites from the sea urchin-associated actinobacterium, Streptomyces sp. HDa1. Molecules, 2018, 23(5) pii:E1032
[http://dx.doi.org/10.3390/molecules23051032]
[64]
Yang, C.; Huang, C.; Zhang, W.; Zhu, Y.; Zhang, C. Heterologous expression of fluostatin gene cluster leads to a bioactive heterodimer. Org. Lett., 2015, 17(21), 5324-5327.
[http://dx.doi.org/10.1021/acs.orglett.5b02683] [PMID: 26465097]
[65]
Wu, Z.C.; Li, S.; Nam, S.J.; Liu, Z.; Zhang, C. Nocardiamides A and B, two cyclohexapeptides from the marine-derived actinomycete Nocardiopsis sp. CNX037. J. Nat. Prod., 2013, 76(4), 694-701.
[http://dx.doi.org/10.1021/np400009a] [PMID: 23586970]
[66]
Bu, Y.Y.; Yamazaki, H.; Ukai, K.; Namikoshi, M. Anti-mycobacterial nucleoside antibiotics from a marine-derived Streptomyces sp. TPU1236A. Mar. Drugs, 2014, 12(12), 6102-6112.
[http://dx.doi.org/10.3390/md12126102] [PMID: 25522318]
[67]
Ellis, G.A.; Wyche, T.P.; Fry, C.G.; Braun, D.R.; Bugni, T.S. Solwaric acids A and B, antibacterial aromatic acids from a marine Solwaraspora sp. Mar. Drugs, 2014, 12(2), 1013-1022.
[http://dx.doi.org/10.3390/md12021013] [PMID: 24534844]
[68]
Eltamany, E.E.; Abdelmohsen, U.R.; Ibrahim, A.K.; Hassanean, H.A.; Hentschel, U.; Ahmed, S.A. New antibacterial xanthone from the marine sponge-derived Micrococcus sp. EG45. Bioorg. Med. Chem. Lett., 2014, 24(21), 4939-4942.
[http://dx.doi.org/10.1016/j.bmcl.2014.09.040] [PMID: 25283555]
[69]
Song, Y.; Li, Q.; Liu, X.; Chen, Y.; Zhang, Y.; Sun, A.; Zhang, W.; Zhang, J.; Ju, J. Cyclic hexapeptides from the deep south china sea-derived streptomyces scopuliridis SCSIO ZJ46 active against pathogenic gram-positive bacteria. J. Nat. Prod., 2014, 77(8), 1937-1941.
[http://dx.doi.org/10.1021/np500399v] [PMID: 25072108]
[70]
Zhou, X.; Huang, H.; Li, J.; Song, Y.; Jiang, R.; Liu, J.; Zhang, S.; Hua, Y.; Ju, J. New anti-infective cycloheptadepsipeptide congeners and absolute stereochemistry from the deep sea-derived Streptomyces drozdowiczii SCSIO 10141. Tetrahedron, 2014, 70(42), 7795-7801.
[http://dx.doi.org/10.1016/j.tet.2014.02.007]
[71]
Leutou, A.S.; Yang, I.; Kang, H.; Seo, E.K.; Nam, S.J.; Fenical, W. Nocarimidazoles A and B from a marine-derived actinomycete of the genus nocardiopsis. J. Nat. Prod., 2015, 78(11), 2846-2849.
[http://dx.doi.org/10.1021/acs.jnatprod.5b00746] [PMID: 26474119]
[72]
Le, T.C.; Yang, I.; Yoon, Y.J.; Nam, S.J.; Fenical, W. Ansalactams B-D illustrate further biosynthetic plasticity within the ansamycin pathway. Org. Lett., 2016, 18(9), 2256-2259.
[http://dx.doi.org/10.1021/acs.orglett.6b00892] [PMID: 27120128]
[73]
Tan, Y. Hu, Y.; Wang, Q.; Zhou, H.; Wang, Y.; Gan, M., Tetrocarcins N and O, glycosidic spirotetronates from a marine-derived Micromonospora sp. identified by PCR-based screening. RSC Advances, 2016, 6(94), 91773-91778.
[http://dx.doi.org/10.1039/C6RA17026A]
[74]
Zhang, Y.; Adnani, N.; Braun, D.R.; Ellis, G.A.; Barns, K.J.; Parker-Nance, S.; Guzei, I.A.; Bugni, T.S. Micromonohalimanes A and B: antibacterial halimane-type diterpenoids from a marine micromonospora species. J. Nat. Prod., 2016, 79(11), 2968-2972.
[http://dx.doi.org/10.1021/acs.jnatprod.6b00555] [PMID: 27813411]
[75]
Nair, V.; Schuhmann, I.; Anke, H.; Kelter, G.; Fiebig, H.H.; Helmke, E.; Laatsch, H. Marine Bacteria, XLVII - psychrotolerant bacteria from extreme antarctic habitats as producers of rare bis- and trisindole Alkaloids. Planta Med., 2016, 82(9-10), 910-918.
[http://dx.doi.org/10.1055/s-0042-108204] [PMID: 27286331]
[76]
Aksoy, S.C.; Uzel, A.; Bedir, E. Cytosine-type nucleosides from marine-derived Streptomyces rochei 06CM016. J. Antibiot. (Tokyo), 2016, 69(1), 51-56.
[http://dx.doi.org/10.1038/ja.2015.72] [PMID: 26126744]
[77]
Park, S.R.; Tripathi, A.; Wu, J.; Schultz, P.J.; Yim, I.; McQuade, T.J.; Yu, F.; Arevang, C.J.; Mensah, A.Y.; Tamayo-Castillo, G.; Xi, C.; Sherman, D.H. Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway. Nat. Commun., 2016, 7, 10710.
[http://dx.doi.org/10.1038/ncomms10710] [PMID: 26880271]
[78]
Lacret, R.; Pérez-Victoria, I.; Oves-Costales, D.; de la Cruz, M.; Domingo, E.; Martín, J.; Díaz, C.; Vicente, F.; Genilloud, O.; Reyes, F. MDN-0170, a New Napyradiomycin from Streptomyces sp. Strain CA-271078. Mar. Drugs, 2016, 14(10)E188
[http://dx.doi.org/10.3390/md14100188] [PMID: 27763545]
[79]
Wang, C.X.; Ding, R.; Jiang, S.T.; Tang, J.S.; Hu, D.; Chen, G.D.; Lin, F.; Hong, K.; Yao, X.S.; Gao, H.; Aldgamycins, J-O. Aldgamycins J-O, 16-Membered Macrolides with a Branched Octose Unit from Streptomycetes sp. and Their Antibacterial Activities. J. Nat. Prod., 2016, 79(10), 2446-2454.
[http://dx.doi.org/10.1021/acs.jnatprod.6b00200] [PMID: 27690254]
[80]
Lacret, R.; Oves-Costales, D.; Gómez, C.; Díaz, C.; de la Cruz, M.; Pérez-Victoria, I.; Vicente, F.; Genilloud, O.; Reyes, F. New ikarugamycin derivatives with antifungal and antibacterial properties from Streptomyces zhaozhouensis. Mar. Drugs, 2014, 13(1), 128-140.
[http://dx.doi.org/10.3390/md13010128] [PMID: 25551780]
[81]
Zhou, S.Y.; Zou, Y.L.; Wang, G.W.; Liao, Z.H.; Chen, M. Two new compounds from a marine-derived Streptomyces sp. J. Asian Nat. Prod. Res., 2017, 19(12), 1172-1176.
[http://dx.doi.org/10.1080/10286020.2017.1307189] [PMID: 28366016]
[82]
Song, Y.; Li, Q.; Qin, F.; Sun, C.; Liang, H.; Wei, X.; Wong, N-K.; Ye, L.; Zhang, Y.; Shao, M.; Ju, J.; Neoabyssomicins, A-C. polycyclic macrolactones from the deep-sea derived Streptomyces koyangensis SCSIO 5802. Tetrahedron, 2017, 73(36), 5366-5372.
[http://dx.doi.org/10.1016/j.tet.2017.07.034]
[83]
Nong, X.H.; Wei, X.Y.; Qi, S.H. Pteridic acids C-G spirocyclic polyketides from the marine-derived Streptomyces sp. SCSGAA 0027. J. Antibiot. (Tokyo), 2017, 70(11), 1047-1052.
[http://dx.doi.org/10.1038/ja.2017.105] [PMID: 28951600]
[84]
Zhang, Z.; Chen, L.; Zhang, X.; Liang, Y.; Anjum, K.; Chen, L.; Lian, X.Y. Bioactive bafilomycins and a new n-arylpyrazinone derivative from marine-derived streptomyces sp. HZP-2216E. Planta Med., 2017, 83(18), 1405-1411.
[http://dx.doi.org/10.1055/s-0043-111897] [PMID: 28571080]
[85]
Kim, J.; Shin, D.; Kim, S.H.; Park, W.; Shin, Y.; Kim, W.K.; Lee, S.K.; Oh, K.B.; Shin, J.; Oh, D.C.; Borrelidins, C-E. Borrelidins C-E: New Antibacterial Macrolides from a Saltern-Derived Halophilic Nocardiopsis sp. Mar. Drugs, 2017, 15(6)E166
[http://dx.doi.org/10.3390/md15060166] [PMID: 28587270]
[86]
Jiang, X.; Zhang, Q.; Zhu, Y.; Nie, F.; Wu, Z.; Yang, C.; Zhang, L.; Tian, X.; Zhang, C. Isolation, structure elucidation and biosynthesis of benzo[ b ]fluorene nenestatin A from deep-sea derived Micromonospora echinospora SCSIO 04089. Tetrahedron, 2017, 73(26), 3585-3590.
[http://dx.doi.org/10.1016/j.tet.2017.03.054]
[87]
Adnani, N.; Chevrette, M.G.; Adibhatla, S.N.; Zhang, F.; Yu, Q.; Braun, D.R.; Nelson, J.; Simpkins, S.W.; McDonald, B.R.; Myers, C.L.; Piotrowski, J.S.; Thompson, C.J.; Currie, C.R.; Li, L.; Rajski, S.R.; Bugni, T.S. Coculture of marine invertebrate-associated bacteria and interdisciplinary technologies enable biosynthesis and discovery of a new antibiotic, keyicin. ACS Chem. Biol., 2017, 12(12), 3093-3102.
[http://dx.doi.org/10.1021/acschembio.7b00688] [PMID: 29121465]
[88]
Zhang, S.; Gui, C.; Shao, M.; Kumar, P.S.; Huang, H.; Ju, J. Antimicrobial tunicamycin derivatives from the deep sea-derived Streptomyces xinghaiensis SCSIO S15077. Nat. Prod. Res., 2018, 1-6.
[http://dx.doi.org/10.1080/14786419.2018.1493736] [PMID: 30445836]
[89]
Wang, J.; Cong, Z.; Huang, X.; Hou, C.; Chen, W.; Tu, Z.; Huang, D.; Liu, Y.; Soliseptide, A.; Soliseptide, A. A Cyclic Hexapeptide Possessing Piperazic Acid Groups from Streptomyces solisilvae HNM30702. Org. Lett., 2018, 20(5), 1371-1374.
[http://dx.doi.org/10.1021/acs.orglett.8b00142] [PMID: 29441782]
[90]
Thirumurugan, D.; Vijayakumar, R. Characterization and structure elucidation of antibacterial compound of Streptomyces sp. ECR77 isolated from east coast of India. Curr. Microbiol., 2015, 70(5), 745-755.
[http://dx.doi.org/10.1007/s00284-015-0780-3] [PMID: 25656264]
[91]
Xiong, Z.Q.; Liu, Q.X.; Pan, Z.L.; Zhao, N.; Feng, Z.X.; Wang, Y. Diversity and bioprospecting of culturable actinomycetes from marine sediment of the Yellow Sea, China. Arch. Microbiol., 2015, 197(2), 299-309.
[http://dx.doi.org/10.1007/s00203-014-1059-y] [PMID: 25416124]
[92]
Lai, Z.; Yu, J.; Ling, H.; Song, Y.; Yuan, J.; Ju, J.; Tao, Y.; Huang, H.; Grincamycins, I-K.; Grincamycins, I. K, Cytotoxic angucycline glycosides derived from marine-derived actinomycete streptomyces lusitanus SCSIO LR32. Planta Med., 2018, 84(3), 201-207.
[http://dx.doi.org/10.1055/s-0043-119888] [PMID: 28950383]
[93]
Cheng, X.; Zhou, B.; Liu, H.; Huo, C.; Ding, W. One new indolocarbazole alkaloid from the Streptomyces sp. A22. Nat. Prod. Res., 2018, 32(21), 2583-2588.
[http://dx.doi.org/10.1080/14786419.2018.1428595] [PMID: 29355042]
[94]
Wang, J.N.; Zhang, H.J.; Li, J.Q.; Ding, W.J.; Ma, Z.J. Bioactive Indolocarbazoles from the Marine-Derived Streptomyces sp. DT-A61. J. Nat. Prod., 2018, 81(4), 949-956.
[http://dx.doi.org/10.1021/acs.jnatprod.7b01058] [PMID: 29558119]
[95]
Jiang, Y.J.; Li, J.Q.; Zhang, H.J.; Ding, W.J.; Ma, Z.J. Cyclizidine-Type Alkaloids from Streptomyces sp. HNA39. J. Nat. Prod., 2018, 81(2), 394-399.
[http://dx.doi.org/10.1021/acs.jnatprod.7b01055] [PMID: 29389122]
[96]
Peng, A.; Qu, X.; Liu, F.; Li, X.; Li, E.; Xie, W. Angucycline Glycosides from an Intertidal Sediments Strain Streptomyces sp. and Their Cytotoxic Activity against Hepatoma Carcinoma Cells. Mar. Drugs, 2018, 16(12)E470
[http://dx.doi.org/10.3390/md16120470] [PMID: 30486371]
[97]
Jiang, Y.J.; Zhang, D.S.; Zhang, H.J.; Li, J.Q.; Ding, W.J.; Xu, C.D.; Ma, Z.J. Medermycin-type naphthoquinones from the marine-derived streptomyces sp. XMA39. J. Nat. Prod., 2018, 81(9), 2120-2124.
[http://dx.doi.org/10.1021/acs.jnatprod.8b00544] [PMID: 30209946]
[98]
Shin, D.; Byun, W.S.; Moon, K.; Kwon, Y.; Bae, M.; Um, S.; Lee, S.K.; Oh, D.C. Coculture of marine streptomyces sp. with bacillus sp. produces a new piperazic acid-bearing cyclic peptide. Front Chem., 2018, 6, 498.
[http://dx.doi.org/10.3389/fchem.2018.00498] [PMID: 30406080]
[99]
Yang, N.; Song, F. Bioprospecting of novel and bioactive compounds from marine actinomycetes isolated from south china sea sediments. Curr. Microbiol., 2018, 75(2), 142-149.
[http://dx.doi.org/10.1007/s00284-017-1358-z] [PMID: 28918535]
[100]
Chen, M.; Chai, W.; Song, T.; Ma, M.; Lian, X.Y.; Zhang, Z. Anti-glioma natural products downregulating tumor glycolytic enzymes from marine actinomycete Streptomyces sp. ZZ406. Sci. Rep., 2018, 8(1), 72.
[http://dx.doi.org/10.1038/s41598-017-18484-7] [PMID: 29311676]
[101]
Zhou, B.; Hu, Z.J.; Zhang, H.J.; Li, J.Q.; Ding, W.J.; Ma, Z.J. Bioactive staurosporine derivatives from the Streptomyces sp. NB-A13. Bioorg. Chem., 2019, 82, 33-40.
[http://dx.doi.org/10.1016/j.bioorg.2018.09.016] [PMID: 30268972]
[102]
El-Hawary, S.S.; Sayed, A.M.; Mohammed, R.; Khanfar, M.A.; Rateb, M.E.; Mohammed, T.A.; Hajjar, D.; Hassan, H.M.; Gulder, T.A.M.; Abdelmohsen, U.R. New pim-1 kinase inhibitor from the co-culture of two sponge-associated actinomycetes. Front Chem., 2018, 6, 538.
[http://dx.doi.org/10.3389/fchem.2018.00538] [PMID: 30525020]
[103]
Harinantenaina Rakotondraibe, L.; Rasolomampianina, R.; Park, H.Y.; Li, J.; Slebodnik, C.; Brodie, P.J.; Blasiak, L.C.; Hill, R.; TenDyke, K.; Shen, Y.; Cassera, M.B.; Rejo, F.; Kingston, D.G. Antiproliferative and antiplasmodial compounds from selected Streptomyces species. Bioorg. Med. Chem. Lett., 2015, 25(23), 5646-5649.
[http://dx.doi.org/10.1016/j.bmcl.2015.07.103] [PMID: 26508548]
[104]
Saha, S.; Zhang, W.; Zhang, G.; Zhu, Y.; Chen, Y.; Liu, W.; Yuan, C.; Zhang, Q.; Zhang, H.; Zhang, L.; Zhang, W.; Zhang, C. Activation and characterization of a cryptic gene cluster reveals a cyclization cascade for polycyclic tetramate macrolactams. Chem. Sci. (Camb.), 2017, 8(2), 1607-1612.
[http://dx.doi.org/10.1039/C6SC03875A] [PMID: 28451290]
[105]
Ye, X.; Anjum, K.; Song, T.; Wang, W.; Liang, Y.; Chen, M.; Huang, H.; Lian, X.Y.; Zhang, Z. Antiproliferative cyclodepsipeptides from the marine actinomycete Streptomyces sp. P11-23B downregulating the tumor metabolic enzymes of glycolysis, glutaminolysis, and lipogenesis. Phytochemistry, 2017, 135, 151-159.
[http://dx.doi.org/10.1016/j.phytochem.2016.12.010] [PMID: 28049552]
[106]
Martucci, H.; Campit, S.E.; Gee, S.R.; Bray, W.M.; Gokey, T.; Cada, A.K.; Yen, T.Y.; Minoura, K.; Guliaev, A.B.; Lokey, R.S.; Amagata, T. Naphthablins B and C, Meroterpenoids Identified from the Marine Sediment-Derived Streptomyces sp. CP26-58 Using HeLa Cell-Based Cytological Profiling. J. Nat. Prod., 2017, 80(3), 684-691.
[http://dx.doi.org/10.1021/acs.jnatprod.6b00996] [PMID: 28128950]
[107]
Asolkar, R.N.; Singh, A.; Jensen, P.R.; Aalbersberg, W.; Carté, B.K.; Feussner, K.D.; Subramani, R.; DiPasquale, A.; Rheingold, A.L.; Fenical, W. Marinocyanins, cytotoxic bromo-phenazinone meroterpenoids from a marine bacterium from the streptomycete clade MAR4. Tetrahedron, 2017, 73(16), 2234-2241.
[http://dx.doi.org/10.1016/j.tet.2017.03.003] [PMID: 28814819]
[108]
Braña, A.F.; Sarmiento-Vizcaíno, A.; Osset, M.; Pérez-Victoria, I.; Martín, J.; de Pedro, N.; de la Cruz, M.; Díaz, C.; Vicente, F.; Reyes, F.; García, L.A.; Blanco, G.; Lobophorin, K. Lobophorin K, a new natural product with cytotoxic activity produced by streptomyces sp. m-207 associated with the deep-sea coral lophelia pertusa. Mar. Drugs, 2017, 15(5)E144
[http://dx.doi.org/10.3390/md15050144] [PMID: 28534807]
[109]
Ding, H.; Wang, J.N.; Zhang, D.S.; Ma, Z.J. Derivatives of Holomycin and Cyclopropaneacetic Acid from Streptomyces sp. DT-A37. Chem. Biodivers., 2017, 14(9)
[http://dx.doi.org/10.1002/cbdv.201700140] [PMID: 28627048]
[110]
Sarmiento-Vizcaíno, A.; Braña, A.F.; Pérez-Victoria, I.; Martín, J.; de Pedro, N.; Cruz, M.; Díaz, C.; Vicente, F.; Acuña, J.L.; Reyes, F.; García, L.A.; Blanco, G.; Paulomycin, G. Paulomycin G, a new natural product with cytotoxic activity against tumor cell lines produced by deep-sea sediment derived micromonospora matsumotoense m-412 from the avilés canyon in the cantabrian Sea. Mar. Drugs, 2017, 15(9)E271
[http://dx.doi.org/10.3390/md15090271] [PMID: 28846627]
[111]
Zhang, Y.M. Liu, B. L.; Zheng, X. H.; Huang, X. J.; Li, H. Y.; Zhang, Y.; Zhang, T. T.; Sun, D. Y.; Lin, B. R.; Zhou, G. X., Anandins A and B, two rare steroidal alkaloids from a marine streptomyces anandii H41-59. Mar. Drugs, 2017, 15(11) pii:E355
[http://dx.doi.org/10.3390/md15110355]
[112]
Abdelfattah, M.S. A new bioactive aminophenoxazinone alkaloid from a marine-derived actinomycete. Nat. Prod. Res., 2013, 27(22), 2126-2131.
[http://dx.doi.org/10.1080/14786419.2013.793686] [PMID: 23656313]
[113]
Fu, P.; Legako, A.; La, S.; MacMillan, J.B. Discovery, characterization, and analogue synthesis of bohemamine dimers generated by non-enzymatic biosynthesis. Chemistry, 2016, 22(10), 3491-3495.
[http://dx.doi.org/10.1002/chem.201600024] [PMID: 26834079]
[114]
Cheng, C.; Othman, E.M.; Stopper, H.; Edrada-Ebel, R.; Hentschel, U.; Abdelmohsen, U.R. Isolation of petrocidin A, a new cytotoxic cyclic dipeptide from the marine sponge-derived bacterium streptomyces sp. SBT348. Mar. Drugs, 2017, 15(12)E383
[http://dx.doi.org/10.3390/md15120383] [PMID: 29211005]
[115]
Abdelfattah, M.S.; Elmallah, M.I.Y.; Mohamed, A.A.; Ishibashi, M. Sharkquinone, a new ana-quinonoid tetracene derivative from marine-derived Streptomyces sp. EGY1 with TRAIL resistance-overcoming activity. J. Nat. Med., 2017, 71(3), 564-569.
[http://dx.doi.org/10.1007/s11418-017-1086-5] [PMID: 28378198]
[116]
Sato, S.; Iwata, F.; Fukae, T.; Katayama, M. Neomacquarimicin: a new macquarimicin analog from marine-derived actinomycete. J. Antibiot. (Tokyo), 2014, 67(6), 479-482.
[http://dx.doi.org/10.1038/ja.2014.17] [PMID: 24594583]
[117]
Shin, H.J.; Lee, H.S.; Lee, J.S.; Shin, J.; Lee, M.A.; Lee, H.S.; Lee, Y.J.; Yun, J.; Kang, J.S. Violapyrones H and I, new cytotoxic compounds isolated from Streptomyces sp. associated with the marine starfish Acanthaster planci. Mar. Drugs, 2014, 12(6), 3283-3291.
[http://dx.doi.org/10.3390/md12063283] [PMID: 24886866]
[118]
Zhang, W.; Ma, L.; Li, S.; Liu, Z.; Chen, Y.; Zhang, H.; Zhang, G.; Zhang, Q.; Tian, X.; Yuan, C.; Zhang, S.; Zhang, W.; Zhang, C.; Indimicins, A-E. bisindole alkaloids from the deep-sea-derived Streptomyces sp. SCSIO 03032. J. Nat. Prod., 2014, 77(8), 1887-1892.
[http://dx.doi.org/10.1021/np500362p] [PMID: 25069084]
[119]
Thomasi, S.S.; Ladeira, C.; Ferreira, D.; da Fontoura Sprenger, R.; Badino, A.C.; Ferreira, A.G.; Venâncio, T. Identification of two new phosphorylated polyketides from a Brazilian streptomycessp. through the use of LC-SPE/NMR. Helv. Chim. Acta, 2016, 99(4), 281-285.
[http://dx.doi.org/10.1002/hlca.201500038]
[120]
Huang, Y.; Jiang, Q.; Chen, Y.H.; Zhang, D.S.; Ding, W.J.; Ma, Z.J. A new medermycin analog from the marine-derived actinomycetes Streptomyces sp. ZS-A45. J. Asian Nat. Prod. Res., 2019, 21(8), 826-831.
[http://dx.doi.org/10.1080/10286020.2018.1478814] [PMID: 29947258]
[121]
Ibrahim, A.H.; Attia, E.Z.; Hajjar, D.; Anany, M.A.; Desoukey, S.Y.; Fouad, M.A.; Kamel, M.S.; Wajant, H.; Gulder, T.A.M.; Abdelmohsen, U.R. New cytotoxic cyclic peptide from the marine sponge-associated nocardiopsis sp. UR67. Mar. Drugs, 2018, 16(9)E290
[http://dx.doi.org/10.3390/md16090290] [PMID: 30134565]
[122]
Kawahara, T.; Fujiwara, T.; Kagaya, N.; Shin-Ya, K. JBIR-150, a novel 20-membered polyene macrolactam from marine-derived Streptomyces sp. OPMA00071. J. Antibiot. (Tokyo), 2018, 71(3), 390-392.
[http://dx.doi.org/10.1038/s41429-017-0010-2] [PMID: 29348521]
[123]
Kim, D.; Lee, E.J.; Lee, J.; Leutou, A.S.; Shin, Y.H.; Choi, B.; Hwang, J.S.; Hahn, D.; Choi, H.; Chin, J.; Cho, S.J.; Hong, Y.D.; Ko, J.; Seong, C.N.; Maloney, K.N.; Oh, D.C.; Yang, I.; Hwang, H.; Nam, S.J. Antartin, a cytotoxic zizaane-type sesquiterpenoid from a streptomyces sp. isolated from an antarctic marine Sediment. Mar. Drugs, 2018, 16(4)E130
[http://dx.doi.org/10.3390/md16040130] [PMID: 29659509]
[124]
Xie, Z.; Zhou, L.; Guo, L.; Yang, X.; Qu, G.; Wu, C.; Zhang, S. Grisemycin, a bridged angucyclinone with a methylsulfinyl moiety from a marine-derived streptomyces sp. Org. Lett., 2016, 18(6), 1402-1405.
[http://dx.doi.org/10.1021/acs.orglett.6b00332] [PMID: 26958869]
[125]
Williams, D.E.; Izard, F.; Arnould, S.; Dalisay, D.S.; Tantapakul, C.; Maneerat, W.; Matainaho, T.; Julien, E.; Andersen, R.J. Structures of Nahuoic Acids B-E Produced in culture by a streptomyces sp. isolated from a marine sediment and evidence for the inhibition of the histone methyl transferase SETD8 in human cancer cells by nahuoic acid A. J. Org. Chem., 2016, 81(4), 1324-1332.
[http://dx.doi.org/10.1021/acs.joc.5b02569] [PMID: 26815947]
[126]
Zhang, S.M.; Zhang, H.Y.; Yang, S.X.; Qu, C.L.; Xie, Z.P.; Pescitelli, G. Isolation, stereochemical study, and cytotoxic activity of isobenzofuran derivatives from a marine Streptomyces sp. Chirality, 2015, 27(1), 82-87.
[http://dx.doi.org/10.1002/chir.22393] [PMID: 25315432]
[127]
Fei, P.; Chuan-Xi, W.; Yang, X.; Hong-Lei, J.; Lu-Jie, C.; Uribe, P.; Bull, A.T.; Goodfellow, M.; Hong, J.; Yun-Yang, L. A new 20-membered macrolide produced by a marine-derived Micromonospora strain. Nat. Prod. Res., 2013, 27(15), 1366-1371.
[http://dx.doi.org/10.1080/14786419.2012.740038] [PMID: 23157320]
[128]
You, Z.Y.; Wang, Y.H.; Zhang, Z.G.; Xu, M.J.; Xie, S.J.; Han, T.S.; Feng, L.; Li, X.G.; Xu, J. Identification of two novel anti-fibrotic benzopyran compounds produced by engineered strains derived from Streptomyces xiamenensis M1-94P that originated from deep-sea sediments. Mar. Drugs, 2013, 11(10), 4035-4049.
[http://dx.doi.org/10.3390/md11104035] [PMID: 24152563]
[129]
Alvarez-Mico, X.; Jensen, P.R.; Fenical, W.; Hughes, C.C. Chlorizidine, a cytotoxic 5H-pyrrolo[2,1-a]isoindol-5-one-containing alkaloid from a marine Streptomyces sp. Org. Lett., 2013, 15(5), 988-991.
[http://dx.doi.org/10.1021/ol303374e] [PMID: 23405849]
[130]
Takada, K.; Ninomiya, A.; Naruse, M.; Sun, Y.; Miyazaki, M.; Nogi, Y.; Okada, S.; Matsunaga, S.; Surugamides, A-E. Surugamides A-E, cyclic octapeptides with four D-amino acid residues, from a marine Streptomyces sp.: LC-MS-aided inspection of partial hydrolysates for the distinction of D- and L-amino acid residues in the sequence. J. Org. Chem., 2013, 78(13), 6746-6750.
[http://dx.doi.org/10.1021/jo400708u] [PMID: 23745669]
[131]
Nam, S.J.; Kauffman, C.A.; Paul, L.A.; Jensen, P.R.; Fenical, W. Actinoranone, a cytotoxic meroterpenoid of unprecedented structure from a marine adapted Streptomyces sp. Org. Lett., 2013, 15(21), 5400-5403.
[http://dx.doi.org/10.1021/ol402080s] [PMID: 24152065]
[132]
Igarashi, I.; Tao, Z.; Seizo, S.; Takashi, M.; Linkai, Y.; Naoya, O. Akaeolide, a Carbocyclic Polyketide from Marine-Derived Streptomyces. Am. Chem. Soc., 2013, 15(22), 5678-5681.
[133]
Fu, P.; Johnson, M.; Chen, H.; Posner, B.A.; MacMillan, J.B.; Carpatamides, A-C. Carpatamides A-C, cytotoxic arylamine derivatives from a marine-derived Streptomyces sp. J. Nat. Prod., 2014, 77(5), 1245-1248.
[http://dx.doi.org/10.1021/np500207p] [PMID: 24754815]
[134]
Fu, P.; Zhu, Y.; Mei, X.; Wang, Y.; Jia, H.; Zhang, C.; Zhu, W. Acyclic congeners from Actinoalloteichus cyanogriseus provide insights into cyclic bipyridine glycoside formation. Org. Lett., 2014, 16(16), 4264-4267.
[http://dx.doi.org/10.1021/ol5019757] [PMID: 25090585]
[135]
Kawahara, T.; Itoh, M.; Izumikawa, M.; Kozone, I.; Sakata, N.; Tsuchida, T.; Shin-ya, K. New hydroxamate metabolite, MBJ-0003, from Micromonospora sp. 29867. J. Antibiot. (Tokyo), 2014, 67(3), 261-263.
[http://dx.doi.org/10.1038/ja.2013.124] [PMID: 24252811]
[136]
Kwon, Y.; Kim, S.H.; Shin, Y.; Bae, M.; Kim, B.Y.; Lee, S.K.; Oh, K.B.; Shin, J.; Oh, D.C. A new benzofuran glycoside and indole alkaloids from a sponge-associated rare actinomycete, Amycolatopsis sp. Mar. Drugs, 2014, 12(4), 2326-2340.
[http://dx.doi.org/10.3390/md12042326] [PMID: 24759001]
[137]
Moon, K.; Ahn, C.H.; Shin, Y.; Won, T.H.; Ko, K.; Lee, S.K.; Oh, K.B.; Shin, J.; Nam, S.I.; Oh, D.C. New benzoxazine secondary metabolites from an arctic actinomycete. Mar. Drugs, 2014, 12(5), 2526-2538.
[http://dx.doi.org/10.3390/md12052526] [PMID: 24796308]
[138]
Liu, D.; Lin, H.; Proksch, P.; Tang, X.; Shao, Z.; Lin, W. Microbacterins A and B, new peptaibols from the deep sea actinomycete Microbacterium sediminis sp. nov. YLB-01(T). Org. Lett., 2015, 17(5), 1220-1223.
[http://dx.doi.org/10.1021/acs.orglett.5b00172] [PMID: 25675340]
[139]
Mullowney, M.W. Ó hAinmhire, E.; Tanouye, U.; Burdette, J.E.; Pham, V.C.; Murphy, B.T. A Pimarane Diterpene and Cytotoxic Angucyclines from a Marine-Derived Micromonospora sp. in Vietnam’s East Sea. Mar. Drugs, 2015, 13(9), 5815-5827.
[http://dx.doi.org/10.3390/md13095815] [PMID: 26389922]
[140]
Gan, M.; Liu, B.; Tan, Y.; Wang, Q.; Zhou, H.; He, H.; Ping, Y.; Yang, Z.; Wang, Y.; Xiao, C.; Saccharothrixones, A-D. Saccharothrixones A-D, tetracenomycin-type polyketides from the marine-derived actinomycete saccharothrix sp. 10-10. J. Nat. Prod., 2015, 78(9), 2260-2265.
[http://dx.doi.org/10.1021/acs.jnatprod.5b00577] [PMID: 26317881]
[141]
Song, Y.; Liu, G.; Li, J.; Huang, H.; Zhang, X.; Zhang, H.; Ju, J. Cytotoxic and antibacterial angucycline- and prodigiosin-analogues from the deep-sea derived Streptomyces sp. SCSIO 11594. Mar. Drugs, 2015, 13(3), 1304-1316.
[http://dx.doi.org/10.3390/md13031304] [PMID: 25786061]
[142]
Vicente, J.; Stewart, A.K.; van Wagoner, R.M.; Elliott, E.; Bourdelais, A.J.; Wright, J.L. Monacyclinones, New Angucyclinone Metabolites Isolated from Streptomyces sp. M7_15 Associated with the Puerto Rican Sponge Scopalina ruetzleri. Mar. Drugs, 2015, 13(8), 4682-4700.
[http://dx.doi.org/10.3390/md13084682] [PMID: 26230704]
[143]
Igarashi, Y.; Asano, D.; Sawamura, M. In, Y.; Ishida, T.; Imoto, M. Ulbactins F and G, polycyclic thiazoline derivatives with tumor cell migration inhibitory activity from Brevibacillus sp. Org. Lett., 2016, 18(7), 1658-1661.
[http://dx.doi.org/10.1021/acs.orglett.6b00531] [PMID: 26998643]
[144]
Ou, Y.X.; Huang, J.F.; Li, X.M.; Kang, Q.J.; Pan, Y.T. Three new 2,5-diketopiperazines from the fish intestinal Streptomyces sp. MNU FJ-36. Nat. Prod. Res., 2016, 30(15), 1771-1775.
[http://dx.doi.org/10.1080/14786419.2015.1137570] [PMID: 26828674]
[145]
Che, Q.; Li, J.; Li, D.; Gu, Q.; Zhu, T. Structure and absolute configuration of drimentine I, an alkaloid from Streptomyces sp. CHQ-64. J. Antibiot. (Tokyo), 2016, 69(6), 467-469.
[http://dx.doi.org/10.1038/ja.2015.133] [PMID: 26732256]
[146]
Che, Q.; Tan, H.; Han, X.; Zhang, X.; Gu, Q.; Zhu, T.; Li, D.; Naquihexcin, A. Naquihexcin A, a s-bridged pyranonaphthoquinone dimer bearing an unsaturated hexuronic acid moiety from a sponge-derived streptomyces sp. HDN-10-293. Org. Lett., 2016, 18(14), 3358-3361.
[http://dx.doi.org/10.1021/acs.orglett.6b01485] [PMID: 27341525]
[147]
Cheng, C.; Othman, E.M.; Fekete, A.; Krischke, M.; Stopper, H.; Edrada-Ebel, R.; Mueller, M.J.; Hentschel, U.; Abdelmohsen, U.R.; Strepoxazine, A. a new cytotoxic phenoxazin from the marine sponge-derived bacterium Streptomyces sp. SBT345. Tetrahedron Lett., 2016, 57(37), 4196-4199.
[http://dx.doi.org/10.1016/j.tetlet.2016.08.005]
[148]
Fu, S.; Wang, F.; Li, H.; Bao, Y.; Yang, Y.; Shen, H.; Lin, B.; Zhou, G. Secondary metabolites from marine-derived Streptomyces antibioticus strain H74-21. Nat. Prod. Res., 2016, 30(21), 2460-2467.
[http://dx.doi.org/10.1080/14786419.2016.1201668] [PMID: 27379435]
[149]
Shaala, L.A.; Youssef, D.T.; Badr, J.M.; Harakeh, S.M. Bioactive 2(1H)-pyrazinones and diketopiperazine alkaloids from a tunicate-derived actinomycete streptomyces sp. Molecules, 2016, 21(9)E1116
[http://dx.doi.org/10.3390/molecules21091116] [PMID: 27563872]
[150]
Chen, Y-H.; Lu, M-C.; Chung, H-M.; Weng, C-F.; Su, J-H.; Yang, Y-T.; Su, Y-D.; Chang, Y-C.; Kuo, J.; Wu, Y-C.; Sung, P-J.; Bafilomycin, M. a new cytotoxic bafilomycin produced by a Streptomyces sp. isolated from a marine sponge Theonella sp. Tetrahedron Lett., 2016, 57(43), 4863-4865.
[http://dx.doi.org/10.1016/j.tetlet.2016.09.066]
[151]
Huang, H.; Li, H.; Qiu, Y.; Hou, L.; Ju, J.; Li, W. A New Dioic Acid from a wbl Gene Mutant of Deepsea-Derived Streptomyces somaliensis SCSIO ZH66. Mar. Drugs, 2016, 14(10)E184
[http://dx.doi.org/10.3390/md14100184] [PMID: 27763499]
[152]
Zhang, S.; Yang, Q.; Guo, L.; Zhang, Y.; Feng, L.; Zhou, L.; Yang, S.; Yao, Q.; Pescitelli, G.; Xie, Z. Isolation, structure elucidation and racemization of (+)- and (-)-pratensilins A-C: unprecedented spiro indolinone-naphthofuran alkaloids from a marine Streptomyces sp. Chem. Commun. (Camb.), 2017, 53(72), 10066-10069.
[http://dx.doi.org/10.1039/C7CC04983H] [PMID: 28840219]
[153]
Bae, M.; Park, S.H.; Kwon, Y.; Lee, S.K.; Shin, J.; Nam, J.W.; Oh, D.C. QM-HiFSA-aided structure determination of succinilenes A-D, new triene polyols from a marine-derived streptomyces sp. Mar. Drugs, 2017, 15(2)E38
[http://dx.doi.org/10.3390/md15020038] [PMID: 28216577]
[154]
Zhu, X.; Duan, Y.; Cui, Z.; Wang, Z.; Li, Z.; Zhang, Y.; Ju, J.; Huang, H. Cytotoxic rearranged angucycline glycosides from deep sea-derived Streptomyces lusitanus SCSIO LR32. J. Antibiot. (Tokyo), 2017, 70(7), 819-822.
[http://dx.doi.org/10.1038/ja.2017.17] [PMID: 28223690]
[155]
Chen, Y-H. Yang, J.-C.; Lu, M.-C.; Weng, C.-F.; Su, Y.-D.; Kuo, J.; Wu, Y.-C.; Sung, P.-J., Bafilomycins N and O, novel cytotoxic bafilomycin analogues produced by Streptomyces sp. GIC10-1 isolated from marine sponge Theonella sp. Tetrahedron, 2017, 73(34), 5170-5175.
[http://dx.doi.org/10.1016/j.tet.2017.07.009]
[156]
Wang, Y.; Wang, L.; Zhuang, Y.; Kong, F.; Zhang, C.; Zhu, W. Phenolic polyketides from the co-cultivation of marine-derived Penicillium sp. WC-29-5 and Streptomyces fradiae 007. Mar. Drugs, 2014, 12(4), 2079-2088.
[http://dx.doi.org/10.3390/md12042079] [PMID: 24714124]
[157]
Pérez, M.; Schleissner, C.; Fernández, R.; Rodríguez, P.; Reyes, F.; Zuñiga, P.; de la Calle, F.; Cuevas, C. PM100117 and PM100118, new antitumor macrolides produced by a marine Streptomyces caniferus GUA-06-05-006A. J. Antibiot. (Tokyo), 2016, 69(5), 388-394.
[http://dx.doi.org/10.1038/ja.2015.121] [PMID: 26648119]
[158]
Liang, Y.; Xie, X.; Chen, L.; Yan, S.; Ye, X.; Anjum, K.; Huang, H.; Lian, X.; Zhang, Z. Bioactive polycyclic quinones from marine streptomyces sp. 182SMLY. Mar. Drugs, 2016, 14(1), 10.
[http://dx.doi.org/10.3390/md14010010] [PMID: 26751456]
[159]
Che, Q.; Qiao, L.; Han, X.; Liu, Y.; Wang, W.; Gu, Q.; Zhu, T.; Li, D.; Anthranosides, A-C. Anthranosides A-C, Anthranilate Derivatives from a Sponge-Derived Streptomyces sp. CMN-62. Org. Lett., 2018, 20(17), 5466-5469.
[http://dx.doi.org/10.1021/acs.orglett.8b02382] [PMID: 30106304]
[160]
Huang, H.; Song, Y.; Li, X.; Wang, X.; Ling, C.; Qin, X.; Zhou, Z.; Li, Q.; Wei, X.; Ju, J. Abyssomicin monomers and dimers from the marine-derived streptomyces koyangensis SCSIO 5802. J. Nat. Prod., 2018, 81(8), 1892-1898.
[http://dx.doi.org/10.1021/acs.jnatprod.8b00448] [PMID: 30070834]
[161]
Kim, S.H.; Ha, T.K.; Oh, W.K.; Shin, J.; Oh, D.C. Antiviral indolosesquiterpenoid xiamycins C-E from a halophilic actinomycete. J. Nat. Prod., 2016, 79(1), 51-58.
[http://dx.doi.org/10.1021/acs.jnatprod.5b00634] [PMID: 26698879]
[162]
Liu, H.; Chen, Z.; Zhu, G.; Wang, L.; Du, Y.; Wang, Y.; Zhu, W. Phenolic polyketides from the marine alga-derived Streptomyces sp. OUCMDZ-3434. Tetrahedron, 2017, 73(36), 5451-5455.
[http://dx.doi.org/10.1016/j.tet.2017.07.052]
[163]
Wang, P.; Xi, L.; Liu, P.; Wang, Y.; Wang, W.; Huang, Y.; Zhu, W. Diketopiperazine derivatives from the marine-derived actinomycete Streptomyces sp. FXJ7.328. Mar. Drugs, 2013, 11(4), 1035-1049.
[http://dx.doi.org/10.3390/md11041035] [PMID: 23538868]
[164]
Yang, A.; Si, L.; Shi, Z.; Tian, L.; Liu, D.; Zhou, D.; Proksch, P.; Lin, W. Nitrosporeusines A and B, unprecedented thioester-bearing alkaloids from the Arctic Streptomyces nitrosporeus. Org. Lett., 2013, 15(20), 5366-5369.
[http://dx.doi.org/10.1021/ol4026809] [PMID: 24090410]
[165]
Lin, Z.; Koch, M.; Pond, C.D.; Mabeza, G.; Seronay, R.A.; Concepcion, G.P.; Barrows, L.R.; Olivera, B.M.; Schmidt, E.W. Structure and activity of lobophorins from a turrid mollusk-associated Streptomyces sp. J. Antibiot. (Tokyo), 2014, 67(1), 121-126.
[http://dx.doi.org/10.1038/ja.2013.115] [PMID: 24220110]
[166]
Sun, Y.; Carandang, R.R.; Harada, Y.; Okada, S.; Yoshitake, K.; Asakawa, S.; Nogi, Y.; Matsunaga, S.; Takada, K.; Lactomycins, A-C. Lactomycins A-C, Dephosphorylated Phoslactomycin Derivatives that Inhibit Cathepsin B, from the Marine-derived Streptomyces sp. ACT232. Mar. Drugs, 2018, 16(2)E70
[http://dx.doi.org/10.3390/md16020070] [PMID: 29466301]
[167]
Sun, Y.; Takada, K.; Nogi, Y.; Okada, S.; Matsunaga, S. Lower homologues of ahpatinin, aspartic protease inhibitors, from a marine Streptomyces sp. J. Nat. Prod., 2014, 77(7), 1749-1752.
[http://dx.doi.org/10.1021/np500337m] [PMID: 24960234]
[168]
Jin, J.; Yang, X.; Liu, T.; Xiao, H.; Wang, G.; Zhou, M.; Liu, F.; Zhang, Y.; Liu, D.; Chen, M.; Cheng, W.; Yang, D.; Ma, M. Fluostatins M-Q Featuring a 6-5-6-6 Ring Skeleton and High Oxidized A-Rings from Marine Streptomyces sp. PKU-MA00045. Mar. Drugs, 2018, 16(3)E87
[http://dx.doi.org/10.3390/md16030087] [PMID: 29522466]
[169]
Abdelfattah, M. S.; Elmallah, M. I. Y.; Faraag, A. H. I.; Hebishy, A. M. S.; Ali, N. H. Heliomycin and tetracinomycin D: anthraquinone derivatives with histone deacetylase inhibitory activity from marine sponge-associated Streptomyces sp. SP9 3 Biotech, 2018, 8(6), 282-4.
[170]
Lin, W.X.; Xie, C.L.; Zhou, M.; Xia, M.L.; Zhou, T.T.; Chen, H.F.; Yang, X.W.; Yang, Q. Chemical constituents from the deep sea-derived Streptomyces xiamenensis MCCC 1A01570 and their effects on RXRα transcriptional regulation. Nat. Prod. Res., 2018, 1-4.
[http://dx.doi.org/10.1080/14786419.2018.1508148] [PMID: 30270742]
[171]
Park, J.S.; Kwon, H.C. New Naphthoquinone terpenoids from marine actinobacterium, streptomyces sp. CNQ-509. Mar. Drugs, 2018, 16(3)E90
[http://dx.doi.org/10.3390/md16030090] [PMID: 29534540]
[172]
Wagner, M.; Abdel-Mageed, W.M.; Ebel, R.; Bull, A.T.; Goodfellow, M.; Fiedler, H.P.; Jaspars, M. Dermacozines H-J isolated from a deep-sea strain of Dermacoccus abyssi from Mariana Trench sediments. J. Nat. Prod., 2014, 77(2), 416-420.
[http://dx.doi.org/10.1021/np400952d] [PMID: 24499261]
[173]
Yim, C.Y.; Le, T.C.; Lee, T.G.; Yang, I.; Choi, H.; Lee, J.; Kang, K.Y.; Lee, J.S.; Lim, K.M.; Yee, S.T.; Kang, H.; Nam, S.J.; Fenical, W.; Saccharomonopyrones, A-C. Saccharomonopyrones A-C, New α-Pyrones from a Marine Sediment-Derived Bacterium Saccharomonospora sp. CNQ-490. Mar. Drugs, 2017, 15(8)E239
[http://dx.doi.org/10.3390/md15080239] [PMID: 28771166]
[174]
Wu, Q.; Deering, R.W.; Zhang, G.; Wang, B.; Li, X.; Sun, J.; Chen, J.; Zhang, H.; Rowley, D.C.; Wang, H. Albisporachelin, a new hydroxamate type siderophore from the deep ocean sediment-derived actinomycete amycolatopsisalbispora WP1T. Mar. Drugs, 2018, 16(6)E199
[http://dx.doi.org/10.3390/md16060199] [PMID: 29875351]
[175]
An, X.; Zhang, B.; Zhang, H.; Li, Y.; Zheng, W.; Yu, Z.; Fu, L.; Zheng, T. Discovery of an algicidal compound from Brevibacterium sp. BS01 and its effect on a harmful algal bloom-causing species, Alexandrium tamarense. Front. Microbiol., 2015, 6, 1235.
[http://dx.doi.org/10.3389/fmicb.2015.01235] [PMID: 26594205]
[176]
Schulze, C.J.; Navarro, G.; Ebert, D.; DeRisi, J.; Linington, R.G.; Salinipostins, A-K. Salinipostins A-K, long-chain bicyclic phosphotriesters as a potent and selective antimalarial chemotype. J. Org. Chem., 2015, 80(3), 1312-1320.
[http://dx.doi.org/10.1021/jo5024409] [PMID: 25584395]
[177]
Raju, R.; Khalil, Z.G.; Piggott, A.M.; Blumenthal, A.; Gardiner, D.L.; Skinner-Adams, T.S.; Capon, R.J.; Mollemycin, A. Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Org. Lett., 2014, 16(6), 1716-1719.
[http://dx.doi.org/10.1021/ol5003913] [PMID: 24611932]
[178]
Zafrir Ilan, E.; Torres, M.R.; Prudhomme, J.; Le Roch, K.; Jensen, P.R.; Fenical, W. Farnesides A and B, sesquiterpenoid nucleoside ethers from a marine-derived Streptomyces sp., strain CNT-372 from Fiji. J. Nat. Prod., 2013, 76(9), 1815-1818.
[http://dx.doi.org/10.1021/np400351t] [PMID: 23987585]
[179]
Abdelmohsen, U.R.; Cheng, C.; Viegelmann, C.; Zhang, T.; Grkovic, T.; Ahmed, S.; Quinn, R.J.; Hentschel, U.; Edrada-Ebel, R. Dereplication strategies for targeted isolation of new antitrypanosomal actinosporins A and B from a marine sponge associated-Actinokineospora sp. EG49. Mar. Drugs, 2014, 12(3), 1220-1244.
[http://dx.doi.org/10.3390/md12031220] [PMID: 24663112]
[180]
Buedenbender, L.; Robertson, L.P.; Lucantoni, L.; Avery, V.M.; Kurtböke, D.I.; Carroll, A.R. HSQC-TOCSY Fingerprinting-Directed Discovery of Antiplasmodial Polyketides from the Marine Ascidian-Derived Streptomyces sp. (USC-16018). Mar. Drugs, 2018, 16(6)E189
[http://dx.doi.org/10.3390/md16060189] [PMID: 29849004]
[181]
Schulze, C.J.; Donia, M.S.; Siqueira-Neto, J.L.; Ray, D.; Raskatov, J.A.; Green, R.E.; McKerrow, J.H.; Fischbach, M.A.; Linington, R.G. Genome-directed lead discovery: biosynthesis, structure elucidation, and biological evaluation of two families of polyene macrolactams against Trypanosoma brucei. ACS Chem. Biol., 2015, 10(10), 2373-2381.
[http://dx.doi.org/10.1021/acschembio.5b00308] [PMID: 26270237]
[182]
Chen, Z.; Hao, J.; Wang, L.; Wang, Y.; Kong, F.; Zhu, W. New α-glucosidase inhibitors from marine algae-derived Streptomyces sp. OUCMDZ-3434. Sci. Rep., 2016, 6, 20004.
[http://dx.doi.org/10.1038/srep20004] [PMID: 26822662]
[183]
Lee, H.W.; Choi, H.; Nam, S.J.; Fenical, W.; Kim, H. Potent Inhibition of Monoamine Oxidase B by a Piloquinone from Marine-Derived Streptomyces sp. CNQ-027. J. Microbiol. Biotechnol., 2017, 27(4), 785-790.
[http://dx.doi.org/10.4014/jmb.1612.12025] [PMID: 28068665]
[184]
Carlson, S.; Marler, L.; Nam, S.J.; Santarsiero, B.D.; Pezzuto, J.M.; Murphy, B.T. Potential chemopreventive activity of a new macrolide antibiotic from a marine-derived Micromonospora sp. Mar. Drugs, 2013, 11(4), 1152-1161.
[http://dx.doi.org/10.3390/md11041152] [PMID: 23552877]
[185]
Ai, W.; Lin, X.P.; Tu, Z.; Tian, X.P.; Lu, X.; Mangaladoss, F.; Zhong, Z.L.; Liu, Y.; Axinelline, A. Axinelline A, a new COX-2 inhibitor from Streptomyces axinellae SCSIO02208. Nat. Prod. Res., 2014, 28(16), 1219-1224.
[http://dx.doi.org/10.1080/14786419.2014.891204] [PMID: 24666327]
[186]
Hassan, H.M.; Boonlarppradab, C.; Fenical, W. Actinoquinolines A and B, anti-inflammatory quinoline alkaloids from a marine-derived Streptomyces sp., strain CNP975. J. Antibiot. (Tokyo), 2016, 69(7), 511-514.
[http://dx.doi.org/10.1038/ja.2016.56] [PMID: 27220408]
[187]
Kim, M.C.; Kwon, O.W.; Park, J.S.; Kim, S.Y.; Kwon, H.C. Nocapyrones H-J, 3,6-disubstituted α-pyrones from the marine actinomycete Nocardiopsis sp. KMF-001. Chem. Pharm. Bull. (Tokyo), 2013, 61(5), 511-515.
[http://dx.doi.org/10.1248/cpb.c12-00956] [PMID: 23386029]
[188]
Li, H.; Huang, H.; Hou, L.; Ju, J.; Li, W. Discovery of Antimycin-Type Depsipeptides from a wbl Gene Mutant Strain of Deepsea-Derived Streptomyces somaliensis SCSIO ZH66 and Their Effects on Pro-inflammatory Cytokine Production. Front. Microbiol., 2017, 8, 678.
[http://dx.doi.org/10.3389/fmicb.2017.00678] [PMID: 28469615]
[189]
Lee, J.; Kim, H.; Lee, T.G.; Yang, I.; Won, D.H.; Choi, H.; Nam, S.J.; Kang, H. Anmindenols A and B, inducible nitric oxide synthase inhibitors from a marine-derived Streptomyces sp. J. Nat. Prod., 2014, 77(6), 1528-1531.
[http://dx.doi.org/10.1021/np500285a] [PMID: 24878306]
[190]
Jiao, R.H.; Xu, H.; Cui, J.T.; Ge, H.M.; Tan, R.X. Neuraminidase inhibitors from marine-derived actinomycete Streptomyces seoulensis. J. Appl. Microbiol., 2013, 114(4), 1046-1053.
[http://dx.doi.org/10.1111/jam.12136] [PMID: 23311635]
[191]
Reimer, A.; Blohm, A.; Quack, T.; Grevelding, C.G.; Kozjak-Pavlovic, V.; Rudel, T.; Hentschel, U.; Abdelmohsen, U.R. Inhibitory activities of the marine streptomycete-derived compound SF2446A2 against Chlamydia trachomatis and Schistosoma mansoni. J. Antibiot. (Tokyo), 2015, 68(11), 674-679.
[http://dx.doi.org/10.1038/ja.2015.54] [PMID: 25990954]
[192]
Cheng, C.; Balasubramanian, S.; Fekete, A.; Krischke, M.; Mueller, M.J.; Hentschel, U.; Oelschlaeger, T.A.; Abdelmohsen, U.R. Inhibitory potential of strepthonium A against Shiga toxin production in enterohemorrhagic Escherichia coli (EHEC) strain EDL933. Nat. Prod. Res., 2017, 31(23), 2818-2823.
[http://dx.doi.org/10.1080/14786419.2017.1297443] [PMID: 28287277]
[193]
Xie, C.L.; Liu, Q.; Xia, J.M.; Gao, Y.; Yang, Q.; Shao, Z.Z.; Liu, G.; Yang, X.W. Anti-allergic compounds from the deep-sea-derived actinomycete nesterenkonia flava MCCC 1K00610. Mar. Drugs, 2017, 15(3)E71
[http://dx.doi.org/10.3390/md15030071] [PMID: 28335419]
[194]
Kobayashi, K.; Fukuda, T.; Usui, T.; Kurihara, Y.; Kanamoto, A.; Tomoda, H.; Bafilomycin, L. Bafilomycin L, a new inhibitor of cholesteryl ester synthesis in mammalian cells, produced by marine-derived Streptomyces sp. OPMA00072. J. Antibiot. (Tokyo), 2015, 68(2), 126-132.
[http://dx.doi.org/10.1038/ja.2014.100] [PMID: 25095804]
[195]
Bae, M.; Moon, K.; Kim, J.; Park, H.J.; Lee, S.K.; Shin, J.; Oh, D.C.; Mohangic Acids, A-E. Mohangic Acids A-E, p-Aminoacetophenonic Acids from a Marine-Mudflat-Derived Streptomyces sp. J. Nat. Prod., 2016, 79(2), 332-339.
[http://dx.doi.org/10.1021/acs.jnatprod.5b00956] [PMID: 26798949]
[196]
Yang, X.W.; Peng, K.; Liu, Z.; Zhang, G.Y.; Li, J.; Wang, N.; Steinmetz, A.; Liu, Y. Strepsesquitriol, a rearranged zizaane-type sesquiterpenoid from the deep-sea-derived actinomycete Streptomyces sp. SCSIO 10355. J. Nat. Prod., 2013, 76(12), 2360-2363.
[http://dx.doi.org/10.1021/np400923c] [PMID: 24490634]
[197]
Harunari, E.; Imada, C.; Igarashi, Y.; Fukuda, T.; Terahara, T.; Kobayashi, T. Hyaluromycin, a new hyaluronidase inhibitor of polyketide origin from marine Streptomyces sp. Mar. Drugs, 2014, 12(1), 491-507.
[http://dx.doi.org/10.3390/md12010491] [PMID: 24451191]
[198]
Kim, H.; Yang, I.; Patil, R.S.; Kang, S.; Lee, J.; Choi, H.; Kim, M.S.; Nam, S.J.; Kang, H.; Anithiactins, A-C. Anithiactins A-C, modified 2-phenylthiazoles from a mudflat-derived Streptomyces sp. J. Nat. Prod., 2014, 77(12), 2716-2719.
[http://dx.doi.org/10.1021/np500558b] [PMID: 25455147]
[199]
Liu, D.; Yang, A.; Wu, C.; Guo, P.; Proksch, P.; Lin, W. Lipid-lowering effects of farnesylquinone and related analogues from the marine-derived Streptomyces nitrosporeus. Bioorg. Med. Chem. Lett., 2014, 24(22), 5288-5293.
[http://dx.doi.org/10.1016/j.bmcl.2014.09.049] [PMID: 25304895]
[200]
Sun, D.; Sun, W.; Yu, Y.; Li, Z.; Deng, Z.; Lin, S. A new glutarimide derivative from marine sponge-derived Streptomyces anulatus S71. Nat. Prod. Res., 2014, 28(19), 1602-1606.
[http://dx.doi.org/10.1080/14786419.2014.928877] [PMID: 24949797]
[201]
Wakimoto, T.; Egami, Y.; Nakashima, Y.; Wakimoto, Y.; Mori, T.; Awakawa, T.; Ito, T.; Kenmoku, H.; Asakawa, Y.; Piel, J.; Abe, I. Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont. Nat. Chem. Biol., 2014, 10(8), 648-655.
[http://dx.doi.org/10.1038/nchembio.1573] [PMID: 24974231]
[202]
Lee, D.S.; Yoon, C.S.; Jung, Y.T.; Yoon, J.H.; Kim, Y.C.; Oh, H. Marine-Derived Secondary Metabolite, Griseusrazin A, Suppresses Inflammation through Heme Oxygenase-1 Induction in Activated RAW264.7 Macrophages. J. Nat. Prod., 2016, 79(4), 1105-1111.
[http://dx.doi.org/10.1021/acs.jnatprod.6b00009] [PMID: 27019105]

Rights & Permissions Print Cite
Article Metrics
181
21
1
2
World Chagas Disease
© 2024 Bentham Science Publishers | Privacy Policy