![conference banner](/images/conference-banner.jpeg)
Abstract
Autophagy, an intricate response to nutrient deprivation, pathogen infection, Endoplasmic Reticulum (ER)-stress and drugs, is crucial for the homeostatic maintenance in living cells. This highly regulated, multistep process has been involved in several diseases including cardiovascular and neurodegenerative diseases, especially in cancer. It can function as either a promoter or a suppressor in cancer, which underlines the potential utility as a therapeutic target. In recent years, increasing evidence has suggested that many natural products could modulate autophagy through diverse signaling pathways, either inducing or inhibiting. In this review, we briefly introduce autophagy and systematically describe several classes of natural products that implicated autophagy modulation. These compounds are of great interest for their potential activity against many types of cancer, such as ovarian, breast, cervical, pancreatic, and so on, hoping to provide valuable information for the development of cancer treatments based on autophagy.
Keywords: Autophagy, cancer, natural products, inhibit, activate, anticancer.
[http://dx.doi.org/10.1186/1749-8546-6-27] [PMID: 21777476]
[http://dx.doi.org/10.1007/s11033-015-3881-y] [PMID: 26033434]
[http://dx.doi.org/10.1155/2015/934207] [PMID: 25821829]
[http://dx.doi.org/10.1111/cpr.12190] [PMID: 26009974]
[http://dx.doi.org/10.1111/j.1365-2184.2012.00833.x] [PMID: 22765290]
[http://dx.doi.org/10.1111/jphp.12034] [PMID: 23647671]
[http://dx.doi.org/10.1155/2012/485042] [PMID: 22988474]
[http://dx.doi.org/10.1016/j.biocel.2013.10.004] [PMID: 24128857]
[http://dx.doi.org/10.1007/BF00174615] [PMID: 2186664]
[http://dx.doi.org/10.1083/jcb.33.2.437] [PMID: 4292315]
[http://dx.doi.org/10.1016/j.jaut.2007.06.003] [PMID: 17693057]
[http://dx.doi.org/10.1016/S1534-5807(04)00099-1] [PMID: 15068787]
[http://dx.doi.org/10.1126/science.1193497] [PMID: 21127245]
[http://dx.doi.org/10.1038/ncb0910-814] [PMID: 20811353]
[PMID: 20637264]
[http://dx.doi.org/10.1038/nrc1692] [PMID: 16148885]
[http://dx.doi.org/10.1016/j.cell.2007.12.018] [PMID: 18191218]
[http://dx.doi.org/10.1016/j.cell.2004.11.046] [PMID: 15680329]
[http://dx.doi.org/10.1038/nrd3802] [PMID: 22935804]
[http://dx.doi.org/10.1002/path.3025] [PMID: 21990109]
[http://dx.doi.org/10.1038/nchembio.79] [PMID: 18391949]
[http://dx.doi.org/10.1523/JNEUROSCI.4390-09.2009] [PMID: 19864570]
[http://dx.doi.org/10.1016/j.nbd.2010.09.009] [PMID: 20887789]
[http://dx.doi.org/10.1038/nature10758] [PMID: 22258505]
[http://dx.doi.org/10.3389/fmicb.2011.00072] [PMID: 21747792]
[http://dx.doi.org/10.1038/nature09782] [PMID: 21248839]
[http://dx.doi.org/10.1016/j.cell.2011.07.030] [PMID: 21884931]
[http://dx.doi.org/10.1097/FJC.0b013e31824cc31c] [PMID: 22343371]
[http://dx.doi.org/10.3858/emm.2012.44.2.033] [PMID: 22257886]
[http://dx.doi.org/10.1097/CAD.0b013e328330d95b] [PMID: 19704371]
[http://dx.doi.org/10.1002/jcb.22869] [PMID: 20830746]
[http://dx.doi.org/10.1111/j.1349-7006.2011.01933.x] [PMID: 21443647]
[http://dx.doi.org/10.1111/bph.14079] [PMID: 29065221]
[http://dx.doi.org/10.1016/j.biopha.2018.03.132] [PMID: 29604589]
[http://dx.doi.org/10.1016/j.fct.2013.09.003] [PMID: 24025684]
[http://dx.doi.org/10.1158/0008-5472.CAN-10-3756] [PMID: 21487045]
[http://dx.doi.org/10.1177/0192623312444471] [PMID: 22563012]
[http://dx.doi.org/10.1124/mol.110.063495] [PMID: 20371669]
[http://dx.doi.org/10.18632/oncotarget.6415] [PMID: 26625315]
[http://dx.doi.org/10.3390/ijms18071343] [PMID: 28644386]
[http://dx.doi.org/10.4161/auto.6886] [PMID: 18818525]
[http://dx.doi.org/10.1124/jpet.108.144113] [PMID: 19139269]
[http://dx.doi.org/10.3390/molecules18021826] [PMID: 23434865]
[http://dx.doi.org/10.1080/10715760802112791] [PMID: 18484413]
[PMID: 22367117]
[http://dx.doi.org/10.1016/j.cbi.2013.06.004] [PMID: 23774672]
[PMID: 24454492]
[http://dx.doi.org/10.1248/bpb.33.1740] [PMID: 20930385]
[http://dx.doi.org/10.3892/or.2014.3173] [PMID: 21519796]
[http://dx.doi.org/10.3892/ijo.2015.3023] [PMID: 26034977]
[http://dx.doi.org/10.3892/ol.2016.4848] [PMID: 27588132]
[http://dx.doi.org/10.1111/jcmm.13049] [PMID: 28026112]
[http://dx.doi.org/10.1093/carcin/bgs295] [PMID: 23002236]
[http://dx.doi.org/10.1016/0272-0590(92)90181-G] [PMID: 1459373]
[http://dx.doi.org/10.1074/jbc.270.11.5830] [PMID: 7890712]
[http://dx.doi.org/10.1207/s15327914nc4801_14] [PMID: 15203384]
[http://dx.doi.org/10.1038/cddis.2009.18] [PMID: 21364620]
[PMID: 23592903]
[http://dx.doi.org/10.1016/j.biopha.2018.04.072] [PMID: 29680738]
[http://dx.doi.org/10.3892/ijo.2014.2339] [PMID: 24626522]
[http://dx.doi.org/10.1016/j.taap.2011.07.008] [PMID: 21803068]
[http://dx.doi.org/10.3892/or.2011.1599] [PMID: 22200845]
[http://dx.doi.org/10.3892/ijo.2013.1791] [PMID: 23354080]
[http://dx.doi.org/10.1002/ptr.5298] [PMID: 25641124]
[http://dx.doi.org/10.1016/j.antiviral.2014.11.003] [PMID: 25446340]
[http://dx.doi.org/10.1016/S0304-3835(02)00349-X] [PMID: 12213285]
[http://dx.doi.org/10.1016/S0006-2952(03)00415-5] [PMID: 12963487]
[http://dx.doi.org/10.1038/sj.onc.1206583] [PMID: 12879015]
[http://dx.doi.org/10.1016/j.canlet.2003.08.023] [PMID: 14670618]
[http://dx.doi.org/10.1016/j.canlet.2004.06.010] [PMID: 15488634]
[http://dx.doi.org/10.1111/j.1442-2042.2004.00973.x] [PMID: 15661057]
[http://dx.doi.org/10.1016/j.ygyno.2006.11.009] [PMID: 17234261]
[http://dx.doi.org/10.1186/1476-4598-8-100] [PMID: 19909554]
[http://dx.doi.org/10.1371/journal.pone.0078958] [PMID: 24205354]
[http://dx.doi.org/10.1007/s11010-014-1974-x] [PMID: 24573886]
[http://dx.doi.org/10.1016/j.vph.2016.02.007] [PMID: 26924458]
[http://dx.doi.org/10.1080/01635580802143836] [PMID: 18584477]
[http://dx.doi.org/10.1158/1535-7163.MCT-08-0236] [PMID: 19001439]
[http://dx.doi.org/10.4161/auto.6.2.10971] [PMID: 20083895]
[http://dx.doi.org/10.18632/oncotarget.19200] [PMID: 29137257]
[http://dx.doi.org/10.3892/ijo.2013.1909] [PMID: 23591552]
[http://dx.doi.org/10.1016/j.carpath.2017.08.001] [PMID: 28985493]
[http://dx.doi.org/10.3390/ijms19010125]
[http://dx.doi.org/10.1186/s12906-016-1320-9] [PMID: 27581091]
[http://dx.doi.org/10.1016/j.canlet.2008.03.046] [PMID: 18467024]
[http://dx.doi.org/10.1089/omi.2008.0075] [PMID: 19207037]
[http://dx.doi.org/10.1093/carcin/bgl232] [PMID: 17148506]
[http://dx.doi.org/10.4161/auto.7.9.15863] [PMID: 21610320]
[http://dx.doi.org/10.1016/j.jnutbio.2016.12.011] [PMID: 28092744]
[http://dx.doi.org/10.1155/2013/596496] [PMID: 24379902]
[http://dx.doi.org/10.1007/s13277-015-3890-4] [PMID: 26260273]
[http://dx.doi.org/10.1007/s10495-016-1334-2] [PMID: 28188387]
[http://dx.doi.org/10.3748/wjg.v17.i18.2288] [PMID: 21633595]
[http://dx.doi.org/10.1080/09553009214551411] [PMID: 1349624]
[http://dx.doi.org/10.1002/(SICI)1099-0844(199703)15:1<27:AID-CBF714>3.0.CO;2-W] [PMID: 9075334]
[http://dx.doi.org/10.1002/tox.20283] [PMID: 17696131]
[http://dx.doi.org/10.1002/mnfr.200800110] [PMID: 19156713]
[http://dx.doi.org/10.1016/j.cellbi.2008.03.019] [PMID: 18538589]
[http://dx.doi.org/10.1254/jphs.09315FP] [PMID: 20431246]
[http://dx.doi.org/10.1248/bpb.34.47] [PMID: 21212516]
[http://dx.doi.org/10.4161/auto.23960] [PMID: 23445752]
[http://dx.doi.org/10.3390/ijms16048415] [PMID: 25884331]
[http://dx.doi.org/10.3892/or.2015.3915] [PMID: 25891311]
[http://dx.doi.org/10.1016/j.bbrc.2015.10.143] [PMID: 26522224]
[http://dx.doi.org/10.1007/s00280-010-1552-1] [PMID: 21207227]
[http://dx.doi.org/10.1002/jcb.24224] [PMID: 22689083]
[http://dx.doi.org/10.3892/ol.2016.5367] [PMID: 28105213]
[http://dx.doi.org/10.1016/j.phymed.2017.12.019] [PMID: 29433678]
[http://dx.doi.org/10.1016/S0006-2952(02)01347-3] [PMID: 12392823]
[http://dx.doi.org/10.1016/j.fct.2012.09.012] [PMID: 23000445]
[http://dx.doi.org/10.3892/or.2014.3294] [PMID: 24970553]
[http://dx.doi.org/10.3892/ol.2018.7852] [PMID: 29541215]
[http://dx.doi.org/10.7314/APJCP.2012.13.1.399] [PMID: 22502710]
[http://dx.doi.org/10.1097/CAD.0b013e3283160fd6] [PMID: 19343001]
[http://dx.doi.org/10.1002/pros.10172] [PMID: 12497584]
[http://dx.doi.org/10.3892/ijmm.21.5.637] [PMID: 18425357]
[http://dx.doi.org/10.3892/ijo.2012.1579] [PMID: 22858649]
[http://dx.doi.org/10.3892/ijo.2013.1942] [PMID: 23677253]
[http://dx.doi.org/10.1016/j.freeradbiomed.2011.06.016] [PMID: 21763418]
[http://dx.doi.org/10.1007/s10495-013-0914-7] [PMID: 24114361]
[http://dx.doi.org/10.1242/bio.026344] [PMID: 28838965]
[http://dx.doi.org/10.3892/or.2018.6365] [PMID: 29658591]
[http://dx.doi.org/10.2174/156652412803833508] [PMID: 22834827]
[http://dx.doi.org/10.1007/978-3-319-41334-1_11] [PMID: 27671820]
[http://dx.doi.org/10.3892/ol.2013.1548] [PMID: 24179537]
[http://dx.doi.org/10.1111/jcmm.13474] [PMID: 29363886]
[http://dx.doi.org/10.1038/s41419-017-0166-5] [PMID: 29410403]
[http://dx.doi.org/10.1016/S0014-2999(98)00635-9] [PMID: 9845274]
[http://dx.doi.org/10.1016/j.bcp.2007.08.016] [PMID: 17900536]
[http://dx.doi.org/10.1002/jcb.10495] [PMID: 12682902]
[http://dx.doi.org/10.1152/ajpgi.00209.2004] [PMID: 15486348]
[http://dx.doi.org/10.1007/s11010-006-9127-5] [PMID: 16691314]
[http://dx.doi.org/10.1124/mol.106.033167] [PMID: 17395690]
[http://dx.doi.org/10.1002/ptr.4645] [PMID: 22388865]
[http://dx.doi.org/10.1254/jphs.13085FP] [PMID: 24048094]
[http://dx.doi.org/10.3892/ol.2017.6565] [PMID: 28928819]
[http://dx.doi.org/10.1371/journal.pone.0146553] [PMID: 26752181]
[http://dx.doi.org/10.1080/10286020903264077] [PMID: 20183254]
[http://dx.doi.org/10.3892/etm.2017.4529] [PMID: 28672972]
[http://dx.doi.org/10.1038/sj.bjc.6605308] [PMID: 19809435]
[http://dx.doi.org/10.1002/jcp.26190] [PMID: 28926094]
[http://dx.doi.org/10.18632/oncotarget.14907] [PMID: 28159921]
[http://dx.doi.org/10.1016/j.ejphar.2018.02.038] [PMID: 29501864]
[http://dx.doi.org/10.1016/j.ejps.2011.04.002] [PMID: 21514382]
[http://dx.doi.org/10.1002/biof.1098] [PMID: 23559532]
[http://dx.doi.org/10.1002/mnfr.201100454] [PMID: 21928294]
[http://dx.doi.org/10.1007/s13273-015-0004-8]
[http://dx.doi.org/10.4161/auto.19471] [PMID: 22622204]
[http://dx.doi.org/10.3892/or.2017.5637] [PMID: 28498433]
[http://dx.doi.org/10.2147/DDDT.S126964] [PMID: 28243065]
[http://dx.doi.org/10.1126/science.275.5297.218] [PMID: 8985016]
[http://dx.doi.org/10.1038/cdd.2008.51] [PMID: 18421301]
[http://dx.doi.org/10.1371/journal.pone.0102535] [PMID: 25068516]
[http://dx.doi.org/10.4161/auto.5.4.7666] [PMID: 19164894]
[http://dx.doi.org/10.1158/0008-5472.CAN-09-3537] [PMID: 20103647]
[http://dx.doi.org/10.1038/srep21772] [PMID: 26902888]
[http://dx.doi.org/10.1002/mc.22324] [PMID: 25917875]
[http://dx.doi.org/10.3892/ijo.2012.1325] [PMID: 22218562]
[http://dx.doi.org/10.1002/mc.22582] [PMID: 27787915]
[http://dx.doi.org/10.1186/s12885-018-4504-5] [PMID: 29788929]
[http://dx.doi.org/10.3892/ijo.2017.3866] [PMID: 28197628]
[http://dx.doi.org/10.1186/1471-2407-9-215] [PMID: 19566920]
[http://dx.doi.org/10.1371/journal.pone.0020849] [PMID: 21695150]
[PMID: 24331535]
[http://dx.doi.org/10.1016/j.canlet.2013.03.023] [PMID: 23541682]
[http://dx.doi.org/10.1111/j.1751-1097.2012.01097.x] [PMID: 22272775]
[http://dx.doi.org/10.1124/jpet.111.189589] [PMID: 22209892]
[http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.487] [PMID: 22094224]
[http://dx.doi.org/10.3390/nu9090927] [PMID: 28837083]
[http://dx.doi.org/10.1016/j.canlet.2003.09.037] [PMID: 15036657]
[http://dx.doi.org/10.1016/j.neuropharm.2006.10.001] [PMID: 17123556]
[http://dx.doi.org/10.1248/bpb.31.826] [PMID: 18451501]
[http://dx.doi.org/10.1271/bbb.90250] [PMID: 19809182]
[http://dx.doi.org/10.1016/j.canlet.2012.01.045] [PMID: 22326284]
[http://dx.doi.org/10.1016/j.biopha.2016.11.072] [PMID: 27899249]
[http://dx.doi.org/10.1038/cddis.2013.273] [PMID: 23907464]
[http://dx.doi.org/10.3390/nu10030328] [PMID: 29518056]
[http://dx.doi.org/10.1007/s11010-012-1265-3] [PMID: 22350816]
[http://dx.doi.org/10.1002/cbin.10634] [PMID: 27296076]
[http://dx.doi.org/10.3892/ijmm.2015.2242] [PMID: 26063203]
[http://dx.doi.org/10.1007/s00018-005-5017-3] [PMID: 15868411]
[http://dx.doi.org/10.1016/j.canlet.2008.01.049] [PMID: 18442668]
[http://dx.doi.org/10.1248/yakushi.129.1403] [PMID: 19881213]
[http://dx.doi.org/10.1186/1471-2407-11-183] [PMID: 21595977]
[http://dx.doi.org/10.1111/j.2042-7158.2011.01371.x] [PMID: 22150682]
[http://dx.doi.org/10.7314/APJCP.2012.13.6.2739] [PMID: 22938451]
[http://dx.doi.org/10.3892/ol.2013.1213] [PMID: 23761818]
[http://dx.doi.org/10.1016/S0031-9422(00)89653-3] [PMID: 7765366]
[http://dx.doi.org/10.1248/cpb.51.790] [PMID: 12843583]
[http://dx.doi.org/10.3892/ijo.23.4.1187] [PMID: 12964003]
[http://dx.doi.org/10.1016/S0367-326X(03)00107-2] [PMID: 12837357]
[http://dx.doi.org/10.1254/jphs.FP0070336] [PMID: 18094523]
[http://dx.doi.org/10.1002/ar.21528] [PMID: 22190546]
[http://dx.doi.org/10.7150/ijbs.4554] [PMID: 22745580]
[http://dx.doi.org/10.1016/j.abb.2009.07.017] [PMID: 19646415]
[http://dx.doi.org/10.1016/j.bbrc.2008.11.038] [PMID: 19026988]
[http://dx.doi.org/10.1038/aps.2011.143] [PMID: 22158107]
[http://dx.doi.org/10.1007/s11010-015-2488-x] [PMID: 26112904]
[PMID: 1361079]
[http://dx.doi.org/10.1016/j.canlet.2011.03.026] [PMID: 21511395]
[http://dx.doi.org/10.3892/ol.2013.1154] [PMID: 23599776]
[http://dx.doi.org/10.1080/01913123.2017.1334019] [PMID: 28691892]
[http://dx.doi.org/10.3892/ijo.2013.1884] [PMID: 23563171]
[http://dx.doi.org/10.1039/C4RA09761K]
[http://dx.doi.org/10.1186/s12935-016-0288-3] [PMID: 26884726]
[http://dx.doi.org/10.1016/j.intimp.2011.01.012] [PMID: 21255694]
[http://dx.doi.org/10.1111/j.1440-1681.2011.05586.x] [PMID: 21834865]
[http://dx.doi.org/10.1053/j.gastro.2010.04.046] [PMID: 20434451]
[http://dx.doi.org/10.3892/etm.2018.5830] [PMID: 29545863]
[http://dx.doi.org/10.1016/j.amjsurg.2013.01.008] [PMID: 23428154]
[http://dx.doi.org/10.18632/oncotarget.6783] [PMID: 26734992]
[http://dx.doi.org/10.1002/jcp.22956] [PMID: 21866552]
[http://dx.doi.org/10.1016/j.neuint.2013.04.005] [PMID: 23619395]
[http://dx.doi.org/10.5483/BMBRep.2014.47.12.069] [PMID: 24667175]
[http://dx.doi.org/10.1038/cddis.2014.543] [PMID: 25611379]
[http://dx.doi.org/10.1093/carcin/bgp069] [PMID: 19329757]
[http://dx.doi.org/10.1002/ijc.28301] [PMID: 23737395]
[http://dx.doi.org/10.1016/j.jnutbio.2012.04.004] [PMID: 22841540]
[http://dx.doi.org/10.1016/j.cbi.2014.04.017] [PMID: 24802810]
[http://dx.doi.org/10.1016/j.jff.2015.05.029]
[http://dx.doi.org/10.3892/etm.2017.4965] [PMID: 29042957]
[PMID: 29374711]
[PMID: 15700827]
[http://dx.doi.org/10.1038/aps.2012.35] [PMID: 22543703]
[http://dx.doi.org/10.1016/j.ejphar.2014.08.006] [PMID: 25160744]
[PMID: 26884987]
[http://dx.doi.org/10.1016/j.redox.2017.03.009] [PMID: 28288416]
[http://dx.doi.org/10.1111/j.1476-5381.2011.01349.x] [PMID: 21418191]
[http://dx.doi.org/10.1159/000481698] [PMID: 28968601]
[http://dx.doi.org/10.1039/C7RA02738A]
[http://dx.doi.org/10.1016/j.foodchem.2013.05.138] [PMID: 23993526]
[http://dx.doi.org/10.4161/auto.8.1.18313] [PMID: 22113202]
[PMID: 21424119]
[http://dx.doi.org/10.1016/j.bbrc.2015.04.102] [PMID: 25935480]
[http://dx.doi.org/10.1038/cddis.2013.358] [PMID: 24091667]
[http://dx.doi.org/10.1016/j.fct.2013.08.007] [PMID: 23939040]
[http://dx.doi.org/10.1158/1535-7163.MCT-08-0361] [PMID: 18723493]
[http://dx.doi.org/10.1016/j.fct.2014.01.014] [PMID: 24444546]
[http://dx.doi.org/10.1016/j.jnutbio.2011.03.014] [PMID: 21820301]
[PMID: 21922137]
[http://dx.doi.org/10.1016/j.ejphar.2013.08.026] [PMID: 24028940]
[http://dx.doi.org/10.3892/ijo.2015.3095] [PMID: 26201693]
[http://dx.doi.org/10.3892/ijmm.2012.1066] [PMID: 22824846]
[http://dx.doi.org/10.3892/mmr.2015.4148] [PMID: 26238746]
[http://dx.doi.org/10.1021/jf901054c] [PMID: 19711916]
[http://dx.doi.org/10.1016/j.fct.2013.02.022] [PMID: 23454208]
[http://dx.doi.org/10.1002/mc.22212] [PMID: 25213258]
[http://dx.doi.org/10.1038/s41419-017-0247-5] [PMID: 29416003]
[http://dx.doi.org/10.1021/cb200492h] [PMID: 22360440]
[http://dx.doi.org/10.1007/s13277-015-3578-9] [PMID: 26014516]
[PMID: 23818925]
[http://dx.doi.org/10.1093/carcin/bgt060] [PMID: 23393227]
[http://dx.doi.org/10.1186/s12943-015-0403-4] [PMID: 26148846]
[http://dx.doi.org/10.1186/1472-6882-12-93]
[http://dx.doi.org/10.1016/j.bbrc.2014.11.102] [PMID: 25482447]
[http://dx.doi.org/10.1080/15548627.2015.1017185] [PMID: 25893854]
[http://dx.doi.org/10.1016/j.foodchem.2012.11.102] [PMID: 23411211]
[http://dx.doi.org/10.1021/acs.jafc.5b04375] [PMID: 26567590]
[http://dx.doi.org/10.1371/journal.pone.0061026] [PMID: 23613775]
[http://dx.doi.org/10.1007/BF02977326] [PMID: 18254244]
[http://dx.doi.org/10.1016/j.bbrc.2011.01.006] [PMID: 21216235]
[http://dx.doi.org/10.1002/mnfr.201000067] [PMID: 20603834]
[http://dx.doi.org/10.1016/j.ejphar.2012.08.001] [PMID: 22939973]
[http://dx.doi.org/10.1016/j.fct.2013.06.059] [PMID: 23850994]
[http://dx.doi.org/10.3390/ijms141122618] [PMID: 24248062]
[http://dx.doi.org/10.3892/or.2012.2131] [PMID: 23151908]
[http://dx.doi.org/10.1016/j.jep.2013.04.051] [PMID: 23684722]
[http://dx.doi.org/10.7150/jca.11291] [PMID: 26078792]
[http://dx.doi.org/10.1371/journal.pone.0147405] [PMID: 26808193]
[http://dx.doi.org/10.1038/cddis.2013.217] [PMID: 23846222]
[http://dx.doi.org/10.1016/j.bcp.2013.01.009] [PMID: 23348250]
[http://dx.doi.org/10.1016/j.bbamcr.2013.07.018] [PMID: 23906794]
[http://dx.doi.org/10.1158/1535-7163.MCT-09-0700] [PMID: 20197400]
[http://dx.doi.org/10.1016/j.jff.2015.07.017]
[http://dx.doi.org/10.3892/ijmm.2016.2585] [PMID: 27177023]
[http://dx.doi.org/10.1007/s10549-012-2175-5] [PMID: 22842972]
[http://dx.doi.org/10.1016/j.fob.2012.05.002] [PMID: 23650588]
[http://dx.doi.org/10.1016/j.biopha.2013.01.013] [PMID: 23582790]
[http://dx.doi.org/10.1186/1756-9966-32-57] [PMID: 23958461]
[http://dx.doi.org/10.1021/jf503968k] [PMID: 25403108]
[http://dx.doi.org/10.3892/or.2014.3239] [PMID: 24912497]
[http://dx.doi.org/10.1016/j.phrs.2017.11.027] [PMID: 29197639]
[http://dx.doi.org/10.1021/acs.jnatprod.7b00347] [PMID: 28719204]
[http://dx.doi.org/10.1021/jf301298y] [PMID: 22860996]
[http://dx.doi.org/10.1007/s00109-011-0763-1] [PMID: 21594580]
[http://dx.doi.org/10.1152/ajplung.00011.2014] [PMID: 25361566]
[http://dx.doi.org/10.1016/j.bbrc.2014.05.101] [PMID: 24887566]
[http://dx.doi.org/10.4161/auto.28034] [PMID: 24642486]
[http://dx.doi.org/10.3390/md12074069] [PMID: 25003791]
[http://dx.doi.org/10.1016/j.jep.2010.06.007] [PMID: 20558270]
[http://dx.doi.org/10.1016/j.canlet.2013.11.001] [PMID: 24280585]
[http://dx.doi.org/10.1002/mc.20780] [PMID: 21520297]
[http://dx.doi.org/10.1038/aps.2010.182] [PMID: 21113177]
[http://dx.doi.org/10.3892/ol.2014.2293] [PMID: 25120662]
[http://dx.doi.org/10.1186/s12885-015-1988-0] [PMID: 26762417]
[http://dx.doi.org/10.1371/journal.pone.0101579] [PMID: 25000169]
[http://dx.doi.org/10.3892/ijo.2014.2659] [PMID: 25231051]
[http://dx.doi.org/10.1016/j.bbrc.2009.11.161] [PMID: 19951696]
[http://dx.doi.org/10.1016/j.biopha.2018.03.089] [PMID: 29605770]
![Wayfinder Image](/images/wayfinder.jpg)