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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 21, 12 Issues, 2021
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access

Aims & Scope

This journal is devoted to full-length/ mini reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to the effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.

Endocrine, Metabolic & Immune Disorders - Drug Targets

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Volume 21

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Number 6







Review Article

Review on Green Synthesis of Silver Nanoparticles through Plants

, 21(6): 994 - 1007

Hoor Shumail, Shah Khalid*, Izhar Ahmad, Haroon Khan, Surriya Amin and Barkat Ullah


DOI: 10.2174/1871530320666200729153714




Research Article



Research Article   Open Access

Hidden Hunger of Vitamin E among Healthy College Students: A Cross- Sectional Study

, 21(6): 1025 - 1030

Zhongqi Wan, Li Wang, Yinyang Xu, Yuanyuan Wang, Tianyou Zhang, Xinlan Mao, Qiao Li, Yangzhi Zhu, Ming Zhou* and Zhong Li*


DOI: 10.2174/1871530321666210101165648


Research Article

Tylophora hirsuta (Wall.) Extracts Ameliorate Diabetes Associated with Inflammation in Alloxan-induced Diabetic Rats

, 21(6): 1031 - 1042

Faisal Razzaque, Ali Sharif*, Bushra Akhtar, Humaira M. Khan, Muhammad F. Akhtar, Maryam Zaib, Abdullah Muhammad, Kashif Sohail, Irfan Hamid and Naeem Qaisar


DOI: 10.2174/1871530320666200821154340




Articles Ahead of Print

TSH Variations in Chronic Heart Failure Outpatients: Clinical Correlates and Outcomes


Paola Terlizzese, Miriam Albanese, Dario Grande, Giuseppe Parisi, Margherita Ilaria Gioia, Natale Daniele Brunetti, Francesco Lisi, Giuseppe Lisco, Francesca Di Serio, Marco Matteo Ciccone, Vincenzo Triggiani* and Massimo Iacoviello


DOI: 10.2174/1871530321666210430131510
View Abstract View on PubMed


Effect of Direct-Acting Antiviral Drugs on Erectile Functions among Hepatitis C Patients: A Prospective Interventional Study


Mohamed Alhefnawy, Ahmed Mohey, Ahmed Fathi, Ahmed Mansour, Sherief Abd-Elsalam*, Ahmed Eissa, Ayman Hagras, Stefano Puliatti and Khaled Almekaty


DOI: 10.2174/1871530321666210212143932
View Abstract View on PubMed







Novel G6PC3 Mutations in Patients with Congenital Neutropenia: Case Reports and Review of the Literature


Seyed Farzad Maroufi, Zoha Shaka, Helia Mojtabavi, Mona Sadeghalvad, Elham Rayzan, Iraj Sedighi, Sepideh Shahkarami, Mehri Najafi, Meino Rohlfs, Christoph Klein and Nima Rezaei*


DOI: 10.2174/1871530321666210616110631
View Abstract View on PubMed



Advancements in Adjuvanticity of Bioactive Inorganic and Organic Compounds


Jhimli Banerjee, Sananda Dey, Kazi Monjur Ali, Biplab Giri* and Sandeep Kumar Dash*


DOI: 10.2174/1871530321666210225104819
View Abstract View on PubMed


Abstracts Ahead of Print

Association between insulin resistance and cardinal rheological parameters in young healthy Japanese individuals during 75 g oral glucose tolerance test


Larasati Martha, Takao Kimura*, Akihiro Yoshida, Katsuhiko Tsunekawa, Tomoyuki Aoki, Osamu Araki, Makoto Nara, Takayuki Ogiwara, Hiroyuki Sumino and Masami Murakami


DOI: 10.2174/1871530321666210720124554
View Abstract


Assessment of Burnout Levels before and during COVID-19 Pandemic: A Web-Based Survey by the (Italian) Association of Medical Endocrinologists (AME).


Yura Loscalzo*, Simonetta Marucci, Piernicola Garofalo, Roberto Attanasio, Giuseppe Lisco*, Vincenzo De Geronimo, Edoardo Guastamacchia, Marco Giannini and Vincenzo Triggiani


DOI: 10.2174/1871530321666210720123336
View Abstract


Genetic Screening of Patients with Thyrotoxic Hypokalemic Periodic Paralysis: An Experience from a Tertiary Care Hospital in the Northeast of Brazil


Cossi Y. Gbefon, Carla P. S. Sobral, Adriana Caldas, Viviane C. C. Rocha, Rossana S. S. Azulay, Gilvan C. Nascimento, Sabrina S. P. Damianse, Silvia A. S. Gaspar, Manuel S. Faria and Marcelo Magalhães*


DOI: 10.2174/1871530321666210719114937
View Abstract




Insulin therapy and outcome from coronavirus disease 2019 (COVID-19): A Systematic Review, Meta-Analysis, and Meta-Regression


Timotius Ivan Hariyanto, Nata Pratama Hardjo Lugito, Theo Audi Yanto, Jeremia Immanuel Siregar and Andree Kurniawan*


DOI: 10.2174/1871530321666210709164925
View Abstract


A case of cancer-associated hyponatraemia: primary adrenal insufficiency secondary to nivolumab


Silvia Galliazzo*, Filippo Morando, Paola Sartorato, Michela Bortolin and Ernesto De Menis


DOI: 10.2174/1871530321666210708142815
View Abstract



Menstrual Disorders Related to Eating Disorders


Walter Milano, Paola Ambrosio, Francesca Carizzone, Valeria De Biasio, Maria Gabriella Foia, Biancamaria Saetta, Maria Francesca Milano and Anna Capasso*


DOI: 10.2174/1871530321666210625145345
View Abstract



Published Contents

Editor's Choice

Acute Versus Chronic Administration of Calcineurin-Inhibitors Differentially Affect T-Cell Function

, 2021; 21(6): 1083 - 1089

Julia Kirchhof, Benjamin Wilde*, Justine Schmidt, Nils Mülling, Liubov Petrakova, Alexandra Brinkhoff, Manfred Schedlowski and Oliver Witzke


DOI: 10.2174/1871530320999200831161710



The Effects of Pemafibrate in Japanese Patients with Type 2 Diabetes Receiving HMG-CoA Reductase Inhibitors

, 2021; 21(5): 919 - 924

Masataka Kusunoki*, Takahiko Sakazaki, Kazuhiko Tsutsumi, Tetsuro Miyata and Yoshiharu Oshida


DOI: 10.2174/1871530320999200818135553



Downregulation of miR-140 is Correlated with Poor Prognosis and Progression of Thyroid Cancer

, 2021; 21(4): 749 - 755

Qianqian Yu, Wenhai Sun, Hui Hua, Yulian Chi, Xiaomin Liu, Anbing Dong, Yinghe Sun, Jianhua Zhang and Ge Guan*


DOI: 10.2174/1871530320666200724180742



T Cell Proliferative Responses and IgG Antibodies to β2GPI in Patients with Diabetes and Atherosclerosis

, 2021; 21(3): 495 - 503

Mohammad R. Monjezi, Hamed Fouladseresht, Shirin Farjadian, Behrouz Gharesi-Fard, Shahdad Khosropanah and Mehrnoosh Doroudchi*


DOI: 10.2174/1871530320666200505115850



Positive Correlation between Circulating Fetuin-A and Severity of Coronary Artery Disease in Men

, 2021; 21(2): 338 - 344

Reza Afrisham, Maliheh Paknejad, Davod Ilbeigi, Sahar Sadegh-Nejadi, Sattar Gorgani-Firuzjaee* and Mahmoud Vahidi*


DOI: 10.2174/1871530320666200601164253




Time-Dependent Effects in Chronic Urticaria: A Time-Series Perspective of Omalizumab Treatment

, 2020; 20(10): 1726 - 1739

Anna Tagka*, George I. Lambrou, Michael Makris, Evangelia Nakou, Electra Nicolaidou , Argyro Chatziioannou and Alexandra Katsarou


DOI: 10.2174/1871530320666200313151720




Modulation of Small Artery Function by Insulin in Young Women: Role of Adiposity

, 2020; 20(8): 1244 - 1252

Moulinath Banerjee*, Linda Shaw, Valentyn Charlton-Menys, Phillip Pemberton, Rayaz Ahmed Malik, John Kennedy Cruickshank and Clare Elizabeth Austin


DOI: 10.2174/1871530320666200428111924




Open Access Articles

Hidden Hunger of Vitamin E among Healthy College Students: A Cross- Sectional Study

, 2021; 21(6): 1025 - 1030

Zhongqi Wan, Li Wang, Yinyang Xu, Yuanyuan Wang, Tianyou Zhang, Xinlan Mao, Qiao Li, Yangzhi Zhu, Ming Zhou* and Zhong Li*




Evaluation of Gamma Amino Butyric Acid (GABA) and Glibenclamide Combination Therapy in Streptozotocin Induced Diabetes

, 2021; 21: 1 - 12 (E-Pub Ahead of Print)

Yunfeng Zhu, Sushma Devi*, Manish Kumar*, Randhir Singh Dahiya and Tarkeshwer




The Skeletal Effects of Gonadotropin-Releasing Hormone Antagonists: A Concise Review

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman and Kok-Yong Chin*




Investigation of ACE rs4646994, MTHFR rs1801133 and VDR rs2228570 Genotypes in Jordanian Patients with Fibromyalgia Syndrome

, 2021; 21: 1 - 9 (E-Pub Ahead of Print)

Raida Khalil, Wajdy J. Al-Awaida, Hamzeh J. Al-Ameer*, Yazun Jarrar, Amer Imraish, Omar Al bawareed, Rand Qawadri, Farah Al Madhoon and Loiy Obeidat





Post-Exercise Ketosis, Salivary Uric Acid and Interleukin-6 after a Simulated Wheelchair Basketball Match

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Anna Raguzzini, Elisabetta Toti, Marco Bernardi, Fabio Castellucci, Valentina Cavedon, Anna Lucia Fedullo, Chiara Milanese, Tommaso Sciarra and Ilaria Peluso*






Appraisal of Anti-Arthritic and Anti-Inflammatory Potential of Folkloric Medicinal Plant Peganum Harmala

, 2021; 21: 1 - 15 (E-Pub Ahead of Print)

Muhammad Furqan Akhtar*, Syed Ahmad Raza, Ammara Saleem*, Irfan Hamid, Mirza Muhammad Faran Ashraf Baig, Ali Sharif, Kashif Sohail, Zeeshan Javaid, Uzma Saleem and Azhar Rasul




Dietary Intakes and Food Habits of Wheelchair Basketball Athletes Compared to Gym Attendees and Individuals who do not Practice Sport Activity

, 2021; 21: 1 - 11 (E-Pub Ahead of Print)

Elisabetta Toti, Valentina Cavedon, Anna Raguzzini, Anna Lucia Fedullo, Chiara Milanese, Elisabetta Bernardi, Sheila Bellito, Marco Bernardi, Tommaso Sciarra and Ilaria Peluso*




Effect of Direct-Acting Antiviral Drugs on Erectile Functions among Hepatitis C Patients: A Prospective Interventional Study

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Mohamed Alhefnawy, Ahmed Mohey, Ahmed Fathi, Ahmed Mansour, Sherief Abd-Elsalam*, Ahmed Eissa, Ayman Hagras, Stefano Puliatti and Khaled Almekaty




Cannabis Sativa L. Flower and Bud Extracts Inhibited In vitro Cholinesterases and b-Secretase Enzymes Activities: Possible Mechanisms of Cannabis Use in Alzheimer Disease

, 2021; 21: 1 - 13 (E-Pub Ahead of Print)

Teboho Mooko, Asis Bala, Satyajit Tripathy, Chethan S. Kumar, Chandrashekara P. Mahadevappa, Sushil K Chaudhary and Motlalepula G. Matsabisa*




Effects of Metformin-Single Therapy on the Level of Inflammatory Markers in Serum of Non-Obese T2DM Patients with NAFLD

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Bojan Mitrovic, Zoran Gluvic*, Djuro Macut, Milan Obradovic, Emina Sudar-Milovanovic, Sanja Soskic, Dragan Stajic and Esma R. Isenovic




Exploration of SQC Formula Effect on Type 2 Diabetes Mellitus by Whole Transcriptome Profile in Rats

, 2021; 21: 1 - 9 (E-Pub Ahead of Print)

Xiaoxu Fu, Xiujuan Zhou, Ya Liu, Yuanhong Lei, Hongyan Xie, Yulin Leng, Hong Gao* and Chunguang Xie*




Body Mass Index and Association of Psychological Stress with Exercise Performance in Military Members: The Cardiorespiratory Fitness and Hospitalization Events in Armed Forces (CHIEF) Study

, 2021; 21: 1 - 7 (E-Pub Ahead of Print)

Ko-Huan Lin, Fang-Ying Su, Szu-Nian Yang, Ming-Wei Liu, Chung-Cheng Kao, Masanori Nagamine and Gen-Min Lin*





Most Cited Articles


Research Article

Probiotics efficacy on oxidative stress values in inflammatory bowel disease: A randomized double-blinded placebo-controlled pilot study

, 2019; 19(3): 373-381.

Andrea Ballini, Luigi Santacroce*, Stefania Cantore, Lucrezia Bottalico, Gianna Dipalma, Skender Topi, Rajiv Saini, Danila De Vito and Francesco Inchingolo


DOI: 10.2174/1871530319666181221150352



Research Article

Hypoglycemic and hypolipemic effects of a new lecithin formulation of bergamot polyphenolic fraction: A double blind, randomized, placebo- controlled study

, 2019; 19(2): 136-143.

Vincenzo Mollace*, Miriam Scicchitano, Sara Paone, Francesca Casale, Carla Calandruccio, Micaela Gliozzi, Vincenzo Musolino, Cristina Carresi, Jessica Maiuolo, Saverio Nucera, Antonella Riva, Pietro Allegrini, Massimo Ronchi, Giovanna Petrangolini and Ezio Bombardelli


DOI: 10.2174/1871530319666181203151513


Review Article

BPA and nutraceuticals, simultaneous effects on endocrine functions

, 2019; 19(5): 594-604.

Stefania D'Angelo, Marika Scafuro and Rosaria Meccariello*


DOI: 10.2174/1871530319666190101120119


Research Article

Evaluation of TG-HDL ratio instead of HOMA ratio as insulin resistance marker in overweight and children with obesity

, 2019; 19(5): 676-682.

Eman G. Behiry*, Nazih Mohamed El Nady, Omima M. AbdEl Haie, May Kamel Mattar and Amira Magdy


DOI: 10.2174/1871530319666190121123535


Clinical Trial

The neuromodulatory effects of ω-3 fatty acids and nano-curcumin on the COX-2/ iNOS network in migraines: A clinical trial study from gene expression to clinical symptoms

, 2019; 19(6): 874-884.

Mina Abdolahi, Arash Jafarieh, Payam Sarraf, Mohsen Sedighiyan, Abolghasem Yousefi, Abbas Tafakhori, Hamed Abdollahi, Farahnaz Salehinia and Mahmoud Djalali*


DOI: 10.2174/1871530319666190212170140


General Research Article

Elucidation of the chemopreventive role of stigmasterol against Jab1 in gall bladder carcinoma

, 2019; 19(6): 826-837.

Pratibha Pandey, Preeti Bajpai*, Mohammad H. Siddiqui, Uzma Sayyed, Rohit Tiwari, Rafia Shekh, Kumudesh Mishra and V.K. Kapoor


DOI: 10.2174/1871530319666190206124120


Research Article

Predictors for fibrosis regression in chronic HCV patients after the treatment with DAAS: Results of a real-world cohort study

, 2020; 20(1): 104-111.

Hanan Soliman, Dina Ziada, Marwa Salama, Manal Hamisa, Rehab Badawi, Nehad Hawash, Amal Selim and Sherief Abd-Elsalam*


DOI: 10.2174/1871530319666190826150344



Research Article

The epithelial barrier model shows that the properties of VSL#3 depend from where it is manufactured

, 2019; 19(2): 199-206.

Paola Palumbo*, Francesca Lombardi, Maria Grazia Cifone and Benedetta Cinque


DOI: 10.2174/1871530318666181022164505


Research Article

Overexpression of hepassocin in diabetic patients with nonalcoholic fatty liver disease may facilitate increased hepatic lipid accumulation

, 2019; 19(2): 185-188.

Ghada Abdelmoemen, Samy Abdelkader Khodeir, Ahmed Nabil Zaki, Maha Kassab, Sabry Abou-Saif and Sherief Abd-Elsalam*


DOI: 10.2174/1871530318666180716100543


Research Article

Sex-specific association between serum uric acid and elevated alanine aminotransferase in a military cohort: The chief study

, 2019; 19(3): 333-340.

Jia-Wei Lin, Kun-Zhe Tsai, Kai-Wen Chen, Fang-Ying Su, Yi-Hwei Li, Yen-Po Lin, Chih-Lu Han, Felicia Lin, Yu-Kai Lin, Chung-Bao Hsieh and Gen-Min Lin*


DOI: 10.2174/1871530319666181129163802


Review Article

Molecular mechanisms of curcumin in neuroinflammatory disorders: A mini review of current evidences

, 2019; 19(3): 247-258.

Mahsa Hatami, Mina Abdolahi, Neda Soveyd, Mahmoud Djalali, Mansoureh Togha and Niyaz Mohammadzadeh Honarvar*


DOI: 10.2174/1871530319666181129103056


General Research Article

25 hydroxyvitamin D levels are negatively and independently associated with fat mass in a cohort of healthy overweight and obese subjects

, 2019; 19(6): 838-844.

Giovanni De Pergola*, Tommaso Martino, Roberta Zupo, Domenico Caccavo, Claudio Pecorella, Silvia Paradiso, Franco Silvestris and Vincenzo Triggiani


DOI: 10.2174/1871530319666190122094039



Most Accessed Articles





The Impact of Comorbid Diabetes Type 2 on Quality of Life in Cancer Patients Undergoing Chemotherapy

, 2021; 21(6): 1017-1024.

Maria Lavdaniti*, Styliani Michalopoulou, Dimitra-Anna Owens, Eugenia Vlachou and Kyriakos Kazakos


DOI: 10.2174/1871530320666200729151715


The Fraction of the Snake Venom, Its Leishmanicidal Effect, and the Stimulation of an Anti-Leishmania Response in Infected Macrophages

, 2021; 21(6): 1115-1124.

Saeideh Nikpour, Fatemeh Tabatabaie*, Iraj Sharifi, Mahshid Mostafavi, Razieh T. Oliaee, Fatemeh Sharifi, Zahra Babaei, Elham Jafari, Ehsan Salarkia and Delavar Shahbazzadeh


DOI: 10.2174/1871530320999201110211222


Review on Green Synthesis of Silver Nanoparticles through Plants

, 2021; 21(6): 994-1007.

Hoor Shumail, Shah Khalid*, Izhar Ahmad, Haroon Khan, Surriya Amin and Barkat Ullah


DOI: 10.2174/1871530320666200729153714



Tylophora hirsuta (Wall.) Extracts Ameliorate Diabetes Associated with Inflammation in Alloxan-induced Diabetic Rats

, 2021; 21(6): 1031-1042.

Faisal Razzaque, Ali Sharif*, Bushra Akhtar, Humaira M. Khan, Muhammad F. Akhtar, Maryam Zaib, Abdullah Muhammad, Kashif Sohail, Irfan Hamid and Naeem Qaisar


DOI: 10.2174/1871530320666200821154340





Vitamin B12 Deficiency Among the Healthy Jordanian Adult Population: Diagnostic Levels, Symptomology and Risk Factors

, 2021; 21(6): 1107-1114.

Amer Abu-Shanab*, Malek Zihlif, Momen N. Rbeihat, Zakaria W. Shkoukani, Alia Khamis, Ula Isleem and Latefa A. Dardas


DOI: 10.2174/1871530320999200831230205



Acute Versus Chronic Administration of Calcineurin-Inhibitors Differentially Affect T-Cell Function

, 2021; 21(6): 1083-1089.

Julia Kirchhof, Benjamin Wilde*, Justine Schmidt, Nils Mülling, Liubov Petrakova, Alexandra Brinkhoff, Manfred Schedlowski and Oliver Witzke


DOI: 10.2174/1871530320999200831161710




Editor-in-Chief

graphic
Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
(Italy)
Biography
View Full Editorial Board

COPE Compliant

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Journal History

Current Drug Targets - Immune, Endocrine & Metabolic Disorders was launched in 2001 and later renamed in 2006 as Endocrine, Metabolic & Immune Disorders - Drug Targets.

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