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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 21, 12 Issues, 2021
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access

Aims & Scope

This journal is devoted to full-length/ mini reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to the effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.

Endocrine, Metabolic & Immune Disorders - Drug Targets

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Volume 21

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Number 8



Perspective   Open Access

Selenium: A Cure for Autoimmune Thyroiditis

, 21(8): 1377 - 1378

Marco Giammanco* and Manfredi Marco Giammanco


DOI: 10.2174/1871530320666201014150147










Research Article

Leptin G-2548A and Leptin Receptor Q223R Gene Polymorphisms are Differently Associated with Oxidative Process in Mexican Mestizo and Indigenous with Obesity

, 21(8): 1413 - 1422

Dealmy Delgadillo-Guzmán*, Alfonso Ibrahim Sharara-Núñez, David Pedroza-Escobar, Irais Castillo-Maldonado and Martha Angélica Quintanar-Escorza


DOI: 10.2174/1871530320666201009161630






Articles Ahead of Print

Circulating Biomarkers Related to Osteocyte and Calcium Homeostasis Between Postmenopausal Women with and without Osteoporosis


Chin Yi Chan, Shaanthana Subramaniam, Norazlina Mohamed, Norliza Muhammad, Fitri Fareez Ramli, Soelaiman Ima-Nirwana and Kok-Yong Chin*


DOI: 10.2174/1871530321666210809154456
View Abstract View on PubMed






Assessment of Burnout Levels Before and During COVID-19 Pandemic: A Web-Based Survey by the (Italian) Association of Medical Endocrinologists (AME)


Yura Loscalzo*, Simonetta Marucci, Piernicola Garofalo, Roberto Attanasio, Giuseppe Lisco*, Vincenzo De Geronimo, Edoardo Guastamacchia, Marco Giannini and Vincenzo Triggiani


DOI: 10.2174/1871530321666210720123336
View Abstract View on PubMed



The Assessment of Some Metabolic Markers by Combination of Ursolic Acid Supplementation and Resistance Training in Young Older Obese Women


Ehsan Asghari, Seyyed Reza Attarzadeh Hosseini, Mina Kiania, Tahereh Farkhondeh, Hamid Arazi and Saeed Samarghandian*


DOI: 10.2174/1871530320666201208105844
View Abstract


Genetic Screening of Patients with Thyrotoxic Hypokalemic Periodic Paralysis: An Experience from a Tertiary Care Hospital in the Northeast of Brazil


Cossi Y. Gbefon, Carla P. S. Sobral, Adriana Caldas, Viviane C. C. Rocha, Rossana S. S. Azulay, Gilvan C. Nascimento, Sabrina S. P. Damianse, Silvia A. S. Gaspar, Manuel S. Faria and Marcelo Magalhães*


DOI: 10.2174/1871530321666210719114937
View Abstract



Abstracts Ahead of Print

Relation between Uric Acid Levels and Subclinical Hypothyroidism in Diabetic Patients


Hosameldeen S. Shabana, Mahmoud Abdelrasheed Allam*, Youssef Abdallah Nassar, Amgad Awad, Magdy M. Naguib, Abdelaleem A. Elgendy and Essam Elmahdi


DOI: 10.2174/1871530321666211018120419
View Abstract


Treponema pallidum (syphilis) antigen TpF1 induces activation of macrophages and accelerates P2X7R-induced NLRP3-dependent release of IL-1β


Dong-Ping Lu*, Jie Jia, Shao-Feng Wei, Wei-Lian Zhang, Rui Liang, Ting Liu, Wen-Zhi Yang, Bing-Yan Li, Rong Zhang* and Fen Wang*


DOI: 10.2174/1871530321666211015091109
View Abstract





The Male Reproductive System and Endocrine Disruptors


Schiesaro Mauro Giovanni *, Amato Anna Maria Letizia, Maneschi Chiara, Sciabica Vincenzo, Pigatto Erika and Sanna Marta


DOI: 10.2174/1871530321666211004100633
View Abstract



Hyperglycemia-induced Immune System Disorders in Diabetes Mellitus and the Concept of Hyperglycemic Memory of Innate Immune Cells: A perspective


Giuseppe Lisco, Vito Angelo Giagulli, Giovanni De Pergola, Edoardo Guastamacchia, Emilio Jirillo* and Vincenzo Triggiani


DOI: 10.2174/1871530321666210924124336
View Abstract



Ivabradine for Uncontrolled Sinus Tachycardia in Thyrotoxic Cardiomyopathy – Case Report


Amit Frenkel*, Yoav Bichovsky, Natan Arotsker, Limor Besser, Ben-Zion Joshua, Merav Fraenkel, Doron Zahger and Moti Klein


DOI: 10.2174/1871530321666210920094411
View Abstract


Published Contents

Editor's Choice

Can Cytokines be used as an Activation Marker in Rheumatoid Arthritis?

, 2021; 21(8): 1459 - 1465

Fatih Öner Kaya, Yeşim Ceylan, Belkız Öngen İpek, Zeynep Güneş Özünal, Gülbüz Sezgin and Selim Nalbant*


DOI: 10.2174/1871530320666201019115030



Benfotiamine Reduces Dendritic Cell Inflammatory Potency

, 2021; 21(7): 1344 - 1351

Neda Djedovic, Iva Božić, Đorđe Miljković* and Irena Lavrnja


DOI: 10.2174/1871530320999200905114135



Acute Versus Chronic Administration of Calcineurin-Inhibitors Differentially Affect T-Cell Function

, 2021; 21(6): 1083 - 1089

Julia Kirchhof, Benjamin Wilde*, Justine Schmidt, Nils Mülling, Liubov Petrakova, Alexandra Brinkhoff, Manfred Schedlowski and Oliver Witzke


DOI: 10.2174/1871530320999200831161710



The Effects of Pemafibrate in Japanese Patients with Type 2 Diabetes Receiving HMG-CoA Reductase Inhibitors

, 2021; 21(5): 919 - 924

Masataka Kusunoki*, Takahiko Sakazaki, Kazuhiko Tsutsumi, Tetsuro Miyata and Yoshiharu Oshida


DOI: 10.2174/1871530320999200818135553



Downregulation of miR-140 is Correlated with Poor Prognosis and Progression of Thyroid Cancer

, 2021; 21(4): 749 - 755

Qianqian Yu, Wenhai Sun, Hui Hua, Yulian Chi, Xiaomin Liu, Anbing Dong, Yinghe Sun, Jianhua Zhang and Ge Guan*


DOI: 10.2174/1871530320666200724180742



T Cell Proliferative Responses and IgG Antibodies to β2GPI in Patients with Diabetes and Atherosclerosis

, 2021; 21(3): 495 - 503

Mohammad R. Monjezi, Hamed Fouladseresht, Shirin Farjadian, Behrouz Gharesi-Fard, Shahdad Khosropanah and Mehrnoosh Doroudchi*


DOI: 10.2174/1871530320666200505115850



Positive Correlation between Circulating Fetuin-A and Severity of Coronary Artery Disease in Men

, 2021; 21(2): 338 - 344

Reza Afrisham, Maliheh Paknejad, Davod Ilbeigi, Sahar Sadegh-Nejadi, Sattar Gorgani-Firuzjaee* and Mahmoud Vahidi*


DOI: 10.2174/1871530320666200601164253




Time-Dependent Effects in Chronic Urticaria: A Time-Series Perspective of Omalizumab Treatment

, 2020; 20(10): 1726 - 1739

Anna Tagka*, George I. Lambrou, Michael Makris, Evangelia Nakou, Electra Nicolaidou , Argyro Chatziioannou and Alexandra Katsarou


DOI: 10.2174/1871530320666200313151720




Open Access Articles

False Positive of 68Ga-DOTATATE PET-CT in a Paraganglioma

, 2021; 21(7): 1352 - 1355

Benedetta Zampetti, Roberto Attanasio*, Marco Boniardi and Renato Cozzi




Exploration of SQC Formula Effect on Type 2 Diabetes Mellitus by Whole Transcriptome Profile in Rats

, 2021; 21(7): 1261 - 1269

Xiaoxu Fu, Xiujuan Zhou, Ya Liu, Yuanhong Lei, Hongyan Xie, Yulin Leng, Hong Gao* and Chunguang Xie*




Hidden Hunger of Vitamin E among Healthy College Students: A Cross- Sectional Study

, 2021; 21(6): 1025 - 1030

Zhongqi Wan, Li Wang, Yinyang Xu, Yuanyuan Wang, Tianyou Zhang, Xinlan Mao, Qiao Li, Yangzhi Zhu, Ming Zhou* and Zhong Li*




Evaluation of Gamma Amino Butyric Acid (GABA) and Glibenclamide Combination Therapy in Streptozotocin Induced Diabetes

, 2021; 21: 1 - 12 (E-Pub Ahead of Print)

Yunfeng Zhu, Sushma Devi*, Manish Kumar*, Randhir Singh Dahiya and Tarkeshwer




The Skeletal Effects of Gonadotropin-Releasing Hormone Antagonists: A Concise Review

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman and Kok-Yong Chin*




Investigation of ACE rs4646994, MTHFR rs1801133 and VDR rs2228570 Genotypes in Jordanian Patients with Fibromyalgia Syndrome

, 2021; 21: 1 - 9 (E-Pub Ahead of Print)

Raida Khalil, Wajdy J. Al-Awaida, Hamzeh J. Al-Ameer*, Yazun Jarrar, Amer Imraish, Omar Al bawareed, Rand Qawadri, Farah Al Madhoon and Loiy Obeidat





Post-Exercise Ketosis, Salivary Uric Acid and Interleukin-6 after a Simulated Wheelchair Basketball Match

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Anna Raguzzini, Elisabetta Toti, Marco Bernardi, Fabio Castellucci, Valentina Cavedon, Anna Lucia Fedullo, Chiara Milanese, Tommaso Sciarra and Ilaria Peluso*






Appraisal of Anti-Arthritic and Anti-Inflammatory Potential of Folkloric Medicinal Plant Peganum Harmala

, 2021; 21: 1 - 15 (E-Pub Ahead of Print)

Muhammad Furqan Akhtar*, Syed Ahmad Raza, Ammara Saleem*, Irfan Hamid, Mirza Muhammad Faran Ashraf Baig, Ali Sharif, Kashif Sohail, Zeeshan Javaid, Uzma Saleem and Azhar Rasul




Dietary Intakes and Food Habits of Wheelchair Basketball Athletes Compared to Gym Attendees and Individuals who do not Practice Sport Activity

, 2021; 21: 1 - 11 (E-Pub Ahead of Print)

Elisabetta Toti, Valentina Cavedon, Anna Raguzzini, Anna Lucia Fedullo, Chiara Milanese, Elisabetta Bernardi, Sheila Bellito, Marco Bernardi, Tommaso Sciarra and Ilaria Peluso*




Effect of Direct-Acting Antiviral Drugs on Erectile Functions among Hepatitis C Patients: A Prospective Interventional Study

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Mohamed Alhefnawy, Ahmed Mohey, Ahmed Fathi, Ahmed Mansour, Sherief Abd-Elsalam*, Ahmed Eissa, Ayman Hagras, Stefano Puliatti and Khaled Almekaty





Cannabis Sativa L. Flower and Bud Extracts Inhibited In vitro Cholinesterases and b-Secretase Enzymes Activities: Possible Mechanisms of Cannabis Use in Alzheimer Disease

, 2021; 21: 1 - 13 (E-Pub Ahead of Print)

Teboho Mooko, Asis Bala, Satyajit Tripathy, Chethan S. Kumar, Chandrashekara P. Mahadevappa, Sushil K Chaudhary and Motlalepula G. Matsabisa*





Most Cited Articles


Research Article

Probiotics efficacy on oxidative stress values in inflammatory bowel disease: A randomized double-blinded placebo-controlled pilot study

, 2019; 19(3): 373-381.

Andrea Ballini, Luigi Santacroce*, Stefania Cantore, Lucrezia Bottalico, Gianna Dipalma, Skender Topi, Rajiv Saini, Danila De Vito and Francesco Inchingolo


DOI: 10.2174/1871530319666181221150352



Review Article

BPA and nutraceuticals, simultaneous effects on endocrine functions

, 2019; 19(5): 594-604.

Stefania D'Angelo, Marika Scafuro and Rosaria Meccariello*


DOI: 10.2174/1871530319666190101120119


Research Article

Hypoglycemic and hypolipemic effects of a new lecithin formulation of bergamot polyphenolic fraction: A double blind, randomized, placebo- controlled study

, 2019; 19(2): 136-143.

Vincenzo Mollace*, Miriam Scicchitano, Sara Paone, Francesca Casale, Carla Calandruccio, Micaela Gliozzi, Vincenzo Musolino, Cristina Carresi, Jessica Maiuolo, Saverio Nucera, Antonella Riva, Pietro Allegrini, Massimo Ronchi, Giovanna Petrangolini and Ezio Bombardelli


DOI: 10.2174/1871530319666181203151513


Clinical Trial

The neuromodulatory effects of ω-3 fatty acids and nano-curcumin on the COX-2/ iNOS network in migraines: A clinical trial study from gene expression to clinical symptoms

, 2019; 19(6): 874-884.

Mina Abdolahi, Arash Jafarieh, Payam Sarraf, Mohsen Sedighiyan, Abolghasem Yousefi, Abbas Tafakhori, Hamed Abdollahi, Farahnaz Salehinia and Mahmoud Djalali*


DOI: 10.2174/1871530319666190212170140


Research Article

Predictors for fibrosis regression in chronic HCV patients after the treatment with DAAS: Results of a real-world cohort study

, 2020; 20(1): 104-111.

Hanan Soliman, Dina Ziada, Marwa Salama, Manal Hamisa, Rehab Badawi, Nehad Hawash, Amal Selim and Sherief Abd-Elsalam*


DOI: 10.2174/1871530319666190826150344


Research Article

Evaluation of TG-HDL ratio instead of HOMA ratio as insulin resistance marker in overweight and children with obesity

, 2019; 19(5): 676-682.

Eman G. Behiry*, Nazih Mohamed El Nady, Omima M. AbdEl Haie, May Kamel Mattar and Amira Magdy


DOI: 10.2174/1871530319666190121123535


General Research Article

Elucidation of the chemopreventive role of stigmasterol against Jab1 in gall bladder carcinoma

, 2019; 19(6): 826-837.

Pratibha Pandey, Preeti Bajpai*, Mohammad H. Siddiqui, Uzma Sayyed, Rohit Tiwari, Rafia Shekh, Kumudesh Mishra and V.K. Kapoor


DOI: 10.2174/1871530319666190206124120


General Research Article

25 hydroxyvitamin D levels are negatively and independently associated with fat mass in a cohort of healthy overweight and obese subjects

, 2019; 19(6): 838-844.

Giovanni De Pergola*, Tommaso Martino, Roberta Zupo, Domenico Caccavo, Claudio Pecorella, Silvia Paradiso, Franco Silvestris and Vincenzo Triggiani


DOI: 10.2174/1871530319666190122094039


Review Article (Mini-Review)

Quality of life in individuals with diabetic foot syndrome

, 2020; 20(9): 1365-1372.

Emmanuel Navarro-Flores and Omar Cauli*


DOI: 10.2174/1871530320666200128154036


Research Article

Anti-cancerous effect of rutin against HPV-C33A cervical cancer cells via g0/g1 cell cycle arrest and apoptotic induction

, 2020; 20(3): 409-418.

Fahad Khan, Pratibha Pandey*, Tarun K. Upadhyay, Asif Jafri, Niraj K. Jha, Rashmi Mishra and Vineeta Singh


DOI: 10.2174/1871530319666190806122257


Research Article

Sex-specific association between serum uric acid and elevated alanine aminotransferase in a military cohort: The chief study

, 2019; 19(3): 333-340.

Jia-Wei Lin, Kun-Zhe Tsai, Kai-Wen Chen, Fang-Ying Su, Yi-Hwei Li, Yen-Po Lin, Chih-Lu Han, Felicia Lin, Yu-Kai Lin, Chung-Bao Hsieh and Gen-Min Lin*


DOI: 10.2174/1871530319666181129163802



Systematic Review Article

The association of metabolic syndrome and psoriasis: A systematic review and meta-analysis of observational study

, 2020; 20(5): 703-717.

Saumya Choudhary, Dibyabhaba Pradhan, Anamika Pandey, Mohd. Kamran Khan, Rohit Lall, V. Ramesh, Poonam Puri, Arun K. Jain* and George Thomas*


DOI: 10.2174/1871530319666191008170409



Most Accessed Articles





Comparison of Salivary Antioxidants and Oxidative Stress Status in Gestational Diabetes Mellitus and Healthy Pregnant Women

, 2021; 21(8): 1485-1490.

Fatemeh Ahmadi-Motamayel*, Shima Fathi, Mohammad Taghi Goodarzi, Shiva Borzouei, Jalal Poorolajal and Yasamin Barakian


DOI: 10.2174/1568026620666201022151059


Two Cases of Double Pituitary Adenomas in a Surgical Series Over 16 Years in a Single Centre

, 2021; 21(8): 1518-1523.

Luca Damiani*, Luca Riccioni, Daniele Nuzzi, Mariella Celico, Riccardo Panzacchi, Cecilia Ragazzini, Luigino Tosatto, Maria Teresa Nasi and Antonio Balestrieri


DOI: 10.2174/1871530321666210203213758




Conservative Management of Gestational Hypercalcemia Due to Primary Hyperparathyroidism with Lack of Complications

, 2021; 21(8): 1512-1517.

Flavia Di Bari*, Roberto Vita, Herbert Marini, Irene Borrielli, Carmela Lo Re, Vincenzo Panebianco and Salvatore Benvenga


DOI: 10.2174/1871530320666201007151331



Effect of Estrogen and Progesterone Hormones on the Expression of Angiotensin II Receptors in the Heart and Aorta of Male Rats

, 2021; 21(8): 1504-1511.

Bahaa Al-Trad*, Osama Abo-Alrob, Yousf Jaradat, Mazhar Al Zoubi, Almuthanna K. Alkarki, Alaa A A Aljabali, Janti Qar, Sahar Omari, Malek Shehab and Bahja Kanan


DOI: 10.2174/1871530320666201023124544



Can Cytokines be used as an Activation Marker in Rheumatoid Arthritis?

, 2021; 21(8): 1459-1465.

Fatih Öner Kaya, Yeşim Ceylan, Belkız Öngen İpek, Zeynep Güneş Özünal, Gülbüz Sezgin and Selim Nalbant*


DOI: 10.2174/1871530320666201019115030


Berberine in the Treatment of Diabetes Mellitus: A Review

, 2021; 21(8): 1379-1386.

Aleksandra Baska*, Kamil Leis and Przemysław Gałązka


DOI: 10.2174/1568026620666201022144405





Editor-in-Chief

graphic
Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
(Italy)
Biography
View Full Editorial Board

COPE Compliant

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Journal History

Current Drug Targets - Immune, Endocrine & Metabolic Disorders was launched in 2001 and later renamed in 2006 as Endocrine, Metabolic & Immune Disorders - Drug Targets.

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