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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 21, 12 Issues, 2021
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

This journal is devoted to full-length/ mini reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to the effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.

Endocrine, Metabolic & Immune Disorders - Drug Targets

,

Volume 20

-

Number 10



Editorial   Open Access



Review Article (Mini-Review)



Review Article



Review Article

Molecular and Immunological Mechanisms Underlying the Various Pharmacological Properties of the Potent Bioflavonoid, Rutin

, 20(10): 1590 - 1596

David O.C. Yong, Sanggetha R. Saker, Dinesh K. Chellappan*, Thiagarajan Madheswaran, Jithendra Panneerselvam, Hira Choudhury, Manisha Pandey, Yik L. Chan, Trudi Collet, Gaurav Gupta, Brian G. Oliver, Peter Wark, Nicole Hansbro, Alan Hsu, Philip M. Hansbro, Kamal Dua* and Farrukh Zeeshan


DOI: 10.2174/1871530320666200503053846
View AbstractView Graphical Abstract


Review Article

MicroRNAs as Biomarker for Breast Cancer

, 20(10): 1597 - 1610

Taru Aggarwal, Ridhima Wadhwa, Riya Gupta, Keshav Raj Paudel, Trudi Collet, Dinesh Kumar Chellappan, Gaurav Gupta, Haribalan Perumalsamy, Meenu Mehta, Saurabh Satija*, Philip M. Hansbro, Kamal Dua and Pawan Kumar Maurya*


DOI: 10.2174/1871530320666200428113051
View AbstractView Graphical Abstract


Review Article



Review Article

Menopausal Remediation and Quality of Life (QoL) Improvement: Insights and Perspectives

, 20(10): 1624 - 1636

Sradhanjali Mohapatra, Zeenat Iqbal*, Sayeed Ahmad, Kanchan Kohli, Uzma Farooq, Santwana Padhi, Mariya Kabir and Ayash K. Panda


DOI: 10.2174/1871530320666200730225830
View AbstractView Graphical Abstract


Review Article

Lead Anti-Obesity Compounds from Nature

, 20(10): 1637 - 1653

Vinesh Dahiya, Neeru Vasudeva*, Sunil Sharma, Ashok Kumar and David Rowley


DOI: 10.2174/1871530320666200504092012
View AbstractView Graphical Abstract


Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 21 (2021) - Number 2


This issue is in progress but contains articles that are final and fully citable.

Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 21 (2021) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

An Overview on COVID-19 and its Effect on Cardiovascular Diseases


Abdullah Hamadi*, Ali Mahzari, Abdulrahim Hakami, Salwa Hindawi, Gasim Dobie, M. I Sayyed, Fawaz Hamdi, Mohammed Nahari and Denise E. Jackson


DOI: 10.2174/1871530321999201228214718
View Abstract




Chronic Diseases and COVID-19: A Review


Mohammed Ajebli, Ayoub Amssayef, Mourad Akdad, Youness Algharrass, Abdelaadim Babakhouya, Dris Ghanimi and Mohamed Eddouks*


DOI: 10.2174/1871530320666201201110148
View Abstract View on PubMed



The Fraction of the Snake Venom, its Leishmanicidal Effect, and the Stimulation of an Anti-Leishmania Response in Infected Macrophages


Saeideh Nikpour, Fatemeh Tabatabaie*, Iraj Sharifi, Mahshid Mostafavi, Razieh Tavakoli Oliaee, Fatemeh Sharifi, Zahra Babaei, Elham Jafari, Ehsan Salarkia and Delavar Shahbazzadeh


DOI: 10.2174/1871530320999201110211222
View Abstract View on PubMed



Covid-19 In Man: A Very Dangerous Affair.


Giuseppe Lisco, Vito A. Giagulli, Giovanni De Pergola, Anna De Tullio, Edoardo Guastamacchia and Vincenzo Triggiani*


DOI: 10.2174/1871530321666210101123801
View Abstract


Thyroid Cancer and Nodules in Graves’ Disease: A Single Center Experience


Claudio Casella, Riccardo Morandi*, Apollonia Verrengia, Alessandro Galani, Sarah Molfino, Dhimiter Cuka, Giacomo Groppo, Carlo Cappelli and Nazario Portolani


DOI: 10.2174/1871530321666201230111911
View Abstract



Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Time-Dependent Effects in Chronic Urticaria: A Time-Series Perspective of Omalizumab Treatment

, 2020; 20(10): 1726 - 1739

Anna Tagka*, George I. Lambrou, Michael Makris, Evangelia Nakou, Electra Nicolaidou , Argyro Chatziioannou and Alexandra Katsarou


DOI: 10.2174/1871530320666200313151720
Abstract




Modulation of Small Artery Function by Insulin in Young Women: Role of Adiposity

, 2020; 20(8): 1244 - 1252

Moulinath Banerjee*, Linda Shaw, Valentyn Charlton-Menys, Phillip Pemberton, Rayaz Ahmed Malik, John Kennedy Cruickshank and Clare Elizabeth Austin


DOI: 10.2174/1871530320666200428111924
Abstract




Interleukin 1-beta is Linked to Chronic Low-Grade Inflammation and Cardiovascular Risk Factors in Overweight Adolescents

, 2020; 20(6): 887 - 894

Gisele A. Amaral, Josilene D. Alves, Adenilda C. Honorio-França, Danny L. Fagundes, Gabriel Gomes Araujo, Nubia S. Lobato, Victor V. Lima and Fernanda R. Giachini*


DOI: 10.2174/1871530319666191116141159
Abstract



Insulin Resistance in Apolipoprotein M Knockout Mice is Mediated by the Protein Kinase Akt Signaling Pathway

, 2020; 20(5): 771 - 780

Shuang Yao, Jun Zhang, Yuxia Zhan, Yuanping Shi, Yang Yu, Lu Zheng, Ning Xu* and Guanghua Luo*


DOI: 10.2174/1871530319666191023125820
Abstract




Dimeric NGF Mimetic Attenuates Hyperglycaemia and DNA Damage in Mice with Streptozotocin-Induced Early-Stage Diabetes

, 2020; 20(3): 453 - 463

Svetlana Yagubova, Aliy Zhanataev, Rita Ostrovskaya*, Еlena Anisina, Тatiana Gudasheva, Аndrey Durnev and Sergey Seredenin


DOI: 10.2174/1871530319666190806115623
Abstract





Open Access Articles

Effects of a Low Carb Diet and Whey Proteins on Anthropometric, Hematochemical, and Cardiovascular Parameters in Subjects with Obesity

, 2020; 20(10): 1719 - 1725

Giovanni De Pergola*, Roberta Zupo, Luisa Lampignano, Silvia Paradiso, Isanna Murro, Annagrazia Cecere, Nicola Bartolomeo, Marco M. Ciccone, Gianluigi Giannelli and Vincenzo Triggiani


Abstract



The Association between Peripheral Blood Cells and the Frailty Syndrome in Patients with Cardiovascular Diseases

, 2020; 20(9): 1419 - 1433

Constantin Bodolea, Elisabeta I. Hiriscau*, Elena-Cristina Buzdugan, Alin I. Grosu, Laurențiu Stoicescu, Ștefan Vesa and Omar Cauli


Abstract


Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 2: Therapeutic Issues

, 2020; 20(8): 1144 - 1155

Renato Cozzi*, Maria R. Ambrosio, Roberto Attanasio, Alessandro Bozzao, Laura De Marinis, Ernesto De Menis, Edoardo Guastamacchia, Andrea Lania, Giovanni Lasio, Francesco Logoluso, Pietro Maffei, Maurizio Poggi, Vincenzo Toscano, Michele Zini, Philippe Chanson and Laurence Katznelson


Abstract


Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 1: Diagnostic and Clinical Issues

, 2020; 20(8): 1133 - 1143

Renato Cozzi*, Maria R. Ambrosio, Roberto Attanasio, Alessandro Bozzao, Laura De Marinis, Ernesto De Menis, Edoardo Guastamacchia, Andrea Lania, Giovanni Lasio, Francesco Logoluso, Pietro Maffei, Maurizio Poggi, Vincenzo Toscano, Michele Zini, Philippe Chanson and Laurence Katznelson


Abstract



Insulin Resistance in Apolipoprotein M Knockout Mice is Mediated by the Protein Kinase Akt Signaling Pathway

, 2020; 20(5): 771 - 780

Shuang Yao, Jun Zhang, Yuxia Zhan, Yuanping Shi, Yang Yu, Lu Zheng, Ning Xu* and Guanghua Luo*


Abstract


Effect on Adipose Tissue of Diabetic Mice Supplemented with n-3 Fatty Acids Extracted from Microalgae

, 2020; 20(5): 728 - 735

Laura E. Gutiérrez-Pliego, Beatriz E. Martínez-Carrillo, Aldo A. Reséndiz-Albor and Roxana Valdés-Ramos*


Abstract


Differential Expression of Resistant and Efflux Pump Genes in MDR-TB Isolates

, 2020; 20(2): 271 - 287

Manaf AlMatar*, Işıl Var, Begüm Kayar and Fatih Köksal


Abstract


Future Perspective of Diabetic Animal Models

, 2020; 20(1): 25 - 38

Shashank Pandey and Magdalena C. Dvorakova*


Abstract


Predictors for Fibrosis Regression in Chronic HCV Patients after the Treatment with DAAS: Results of a Real-world Cohort Study

, 2020; 20(1): 104 - 111

Hanan Soliman, Dina Ziada, Marwa Salama, Manal Hamisa, Rehab Badawi, Nehad Hawash, Amal Selim and Sherief Abd-Elsalam*


Abstract







Most Cited Articles


Research Article

Predictors for fibrosis regression in chronic HCV patients after the treatment with DAAS: Results of a real-world cohort study

, 2020; 20(1): 104-111.

Hanan Soliman, Dina Ziada, Marwa Salama, Manal Hamisa, Rehab Badawi, Nehad Hawash, Amal Selim and Sherief Abd-Elsalam*


DOI: 10.2174/1871530319666190826150344
Abstract


Review Article

Peripheral immunosenescence and central neuroinflammation: A dangerous liaison - A dietary approach

, 2020; 20(9): 1391-1411.

Thea Magrone*, Manrico Magrone, Matteo A. Russo and Emilio Jirillo


DOI: 10.2174/1871530320666200406123734
Abstract


Review Article

Immune-inflammation in atherosclerosis: A new twist in an old tale

, 2020; 20(4): 525-545.

Atefe Ghamar Talepoor, Hamed Fouladseresht, Shahdad Khosropanah and Mehrnoosh Doroudchi*


DOI: 10.2174/1871530319666191016095725
Abstract


Review Article (Mini-Review)

Quality of life in individuals with diabetic foot syndrome

, 2020; 20(9): 1365-1372.

Emmanuel Navarro-Flores and Omar Cauli*


DOI: 10.2174/1871530320666200128154036
Abstract


Research Article

Anti-cancerous effect of rutin against HPV-C33A cervical cancer cells via g0/g1 cell cycle arrest and apoptotic induction

, 2020; 20(3): 409-418.

Fahad Khan, Pratibha Pandey*, Tarun K. Upadhyay, Asif Jafri, Niraj K. Jha, Rashmi Mishra and Vineeta Singh


DOI: 10.2174/1871530319666190806122257
Abstract


Review Article

Lncrna, important player in bone development and disease

, 2020; 20(1): 50-66.

Dijie Li, Chaofei Yang, Chong Yin, Fan Zhao, Zhihao Chen, Ye Tian, Kai Dang, Shanfeng Jiang, Wenjuan Zhang, Ge Zhang and Airong Qian*


DOI: 10.2174/1871530319666190904161707
Abstract


Research Article

The preventive effect of IL-1beta antagonist on diabetic peripheral neuropathy

, 2020; 20(5): 753-759.

Zheng Hangping , Han Ling, Ji Lijin, Zhao Wenting, Liu Xiaoxia, Zhang Qi, Zhu Xiaoming, Li Qingchun, Li Yiming, Xiong Qian, Hu Ji, Lu Bin* and Zhang Shuo*


DOI: 10.2174/1871530319666191022114139
Abstract


Research Article

The association between Hba1c levels, olfactory memory and cognition in normal, pre-diabetic and diabetic persons

, 2020; 20(2): 198-212.

Burak Yulug*, Ozlem Saatci, Aysun Işıklar, Lutfu Hanoglu, Ulkan Kilic, Mehmet Ozansoy, Seyda Cankaya, Baris Cankaya and Ertugrul Kilic


DOI: 10.2174/1871530319666190614121738
Abstract


Review Article

Diagnostic approach to the patients with suspected primary immunodeficiency

, 2020; 20(2): 157-171.

Marzieh Tavakol, Mahnaz Jamee, Gholamreza Azizi*, Homa Sadri, Yasser Bagheri, Majid Zaki-Dizaji, Fatemeh Sadat Mahdavi, Farhad Jadidi-Niaragh, Sanaz Tajfirooz, Ali N. Kamali, Fatemeh Aghamahdi, Shahab Noorian, Habibeh Taghavi Kojidi, Mehdi Mosavian, Rahman Matani, Elahe Dolatshahi, Kumars Porrostami, Nasrin Elahimehr, Marzie Fatemi-Abhari, Laleh Sharifi, Reza Arjmand, Sabahat Haghi, Hamed Zainaldain, Reza Yazdani, Mohammadreza Shaghaghi, Hassan Abolhassani and Asghar Aghamohammadi


DOI: 10.2174/1871530319666190828125316
Abstract


Clinical Trial

The effect of vitamin D supplementation on clinical outcomes of asthmatic children with vitamin D insufficiency

, 2020; 20(1): 149-155.

Rasoul N. Kalmarzi, Sivan Ahmadi, Ramesh Rahehagh, Asadollah Fathallahpour, Behzad Khalafi, Hajar Kashefi, Daem Roshani, Rama N. Zaryan, Shilan Mohamadi and Wesam Kooti*


DOI: 10.2174/1871530319666190426161809
Abstract



Review Article

Molecular and immunological mechanisms underlying the various pharmacological properties of the potent bioflavonoid, rutin

, 2020; 20(10): 1590-1596.

David O.C. Yong, Sanggetha R. Saker, Dinesh K. Chellappan*, Thiagarajan Madheswaran, Jithendra Panneerselvam, Hira Choudhury, Manisha Pandey, Yik L. Chan, Trudi Collet, Gaurav Gupta, Brian G. Oliver, Peter Wark, Nicole Hansbro, Alan Hsu, Philip M. Hansbro, Kamal Dua* and Farrukh Zeeshan


DOI: 10.2174/1871530320666200503053846
Abstract


Research Article

Hepatocyte growth factor attenuates the development of TGF-Β1- induced EndMT through down-regulating the notch signaling

, 2020; 20(5): 781-787.

Ruiping Yang, Fan Yang, Yingchun Hu, Muhu Chen, Ying Liu, Jinpeng Li and Wu Zhong*


DOI: 10.2174/1871530319666191023141638
Abstract




Most Accessed Articles

Effects of a Low Carb Diet and Whey Proteins on Anthropometric, Hematochemical, and Cardiovascular Parameters in Subjects with Obesity

, 2020; 20(10): 1719-1725.

Giovanni De Pergola*, Roberta Zupo, Luisa Lampignano, Silvia Paradiso, Isanna Murro, Annagrazia Cecere, Nicola Bartolomeo, Marco M. Ciccone, Gianluigi Giannelli and Vincenzo Triggiani


DOI: 10.2174/1871530320666200610143724
Abstract



MicroRNAs as Biomarker for Breast Cancer

, 2020; 20(10): 1597-1610.

Taru Aggarwal, Ridhima Wadhwa, Riya Gupta, Keshav Raj Paudel, Trudi Collet, Dinesh Kumar Chellappan, Gaurav Gupta, Haribalan Perumalsamy, Meenu Mehta, Saurabh Satija*, Philip M. Hansbro, Kamal Dua and Pawan Kumar Maurya*


DOI: 10.2174/1871530320666200428113051
Abstract


Lead Anti-Obesity Compounds from Nature

, 2020; 20(10): 1637-1653.

Vinesh Dahiya, Neeru Vasudeva*, Sunil Sharma, Ashok Kumar and David Rowley


DOI: 10.2174/1871530320666200504092012
Abstract


Time-Dependent Effects in Chronic Urticaria: A Time-Series Perspective of Omalizumab Treatment

, 2020; 20(10): 1726-1739.

Anna Tagka*, George I. Lambrou, Michael Makris, Evangelia Nakou, Electra Nicolaidou , Argyro Chatziioannou and Alexandra Katsarou


DOI: 10.2174/1871530320666200313151720
Abstract


Serum Thyroid Peroxidase Antibody Level and Incident Hypertension in Iranian Men: A Suggestion for the Role of Thyroid Autoimmunity

, 2020; 20(10): 1711-1718.

Maryam Tohidi, Aidin Baghbani-Oskouei, Atieh Amouzegar, Ladan Mehran, Fereidoun Azizi and Farzad Hadaegh*


DOI: 10.2174/1871530320666200624163035
Abstract


Molecular and Immunological Mechanisms Underlying the Various Pharmacological Properties of the Potent Bioflavonoid, Rutin

, 2020; 20(10): 1590-1596.

David O.C. Yong, Sanggetha R. Saker, Dinesh K. Chellappan*, Thiagarajan Madheswaran, Jithendra Panneerselvam, Hira Choudhury, Manisha Pandey, Yik L. Chan, Trudi Collet, Gaurav Gupta, Brian G. Oliver, Peter Wark, Nicole Hansbro, Alan Hsu, Philip M. Hansbro, Kamal Dua* and Farrukh Zeeshan


DOI: 10.2174/1871530320666200503053846
Abstract




Menopausal Remediation and Quality of Life (QoL) Improvement: Insights and Perspectives

, 2020; 20(10): 1624-1636.

Sradhanjali Mohapatra, Zeenat Iqbal*, Sayeed Ahmad, Kanchan Kohli, Uzma Farooq, Santwana Padhi, Mariya Kabir and Ayash K. Panda


DOI: 10.2174/1871530320666200730225830
Abstract


Autumn Royal and Egnatia Grape Extracts Differently Modulate Cell Proliferation in Human Colorectal Cancer Cells

, 2020; 20(10): 1740-1750.

Isabella Gigante, Rosa Anna Milella, Valeria Tutino, Giambattista Debiase, Luciano Notarangelo, Maria Angela Giannandrea, Valentina De Nunzio, Antonella Orlando, Rosalba D’Alessandro, Maria Gabriella Caruso and Maria Notarnicola*


DOI: 10.2174/1871530320666200421102418
Abstract







Editor-in-Chief

Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
(Italy)
Biography
View Full Editorial Board

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Journal History

Current Drug Targets - Immune, Endocrine & Metabolic Disorders was launched in 2001 and later renamed in 2006 as Endocrine, Metabolic & Immune Disorders - Drug Targets.

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