Thalassemia is one of the most common genetic diseases in the world. It has a relatively higher incidence in Mediterranean and Middle Eastern countries and presents a major public health and social challenge. This monograph updates the reader on the dental and orofacial characteristics of thalassemia major in Arab populations. Since very few detailed studies on these topics among Arabs have been published, the monograph attempts to bridge the knowledge gap in this area. Clinical, radiographic and odontometric features of the typical thalassemia major patient are clearly described in this book. </P> Key Features </P> - Provides a ready reference for dental and orofacial features in thalassemia major including a review of appropriate dental care </P> - Covers the pathogenesis, systemic complications, morbidity and mortality, management, and prevention of thalassemia major. </P> - Provides guidelines for optimal dental care. </P> - Covers special topics such as epidemiology, consanguinity, hematologic diagnosis, genetic testing, literature review, diet and nutrition, cost of treatment, and prevention </P> - Includes colored photographs, radiographs, drawings, tables, and 2 plates to illustrate examples and information </P> - Provides references for further reading </P> This monograph is a handy reference for medical and dental students, and caregivers on the subject of clinical dentistry in thalassemia patients.

Influenza is one of the most ancient and intriguing diseases that has been accompanying our civilization for millennia. While mankind has successfully defeated many dangerous influenza infections in the last couple of centuries, influenza control remains a serious problem for public health. A number of influenza vaccines and antiviral compounds have been licensed in recent times. However, the influenza virus is still ahead of us, as it continues to persistently infect humans to this day. Influenza: A Century of Research shows how influenza virology has developed historically and the tremendous knowledge that has been uncovered in the study of influenza. In this monograph, the authors present a historical perspective on influenza, chronologically, with an emphasis on its virology. Chapters cover information about the isolation of the first influenza viruses, substrates, and models for studying influenza, structure, and life cycle of the influenza virus, mechanisms of attenuation and virulence. Chapters progress into the multidisciplinary aspects of influenza research such as influenza virus ecology and the evolutionary origin of epidemic and pandemic influenza viruses. A significant part of the book also covers the description of the prevention and treatment of influenza and reasons that have contributed to insufficient control for influenza. The questions of how the COVID-19 pandemic affects the circulation of seasonal respiratory viruses, and if we can eliminate this virus are also addressed. Influenza: A Century of Research is an informative source of information for a broad range of readers, academic or otherwise, who are interested in knowing more about the disease.

Frontiers in Clinical Drug Research &amp;amp;ndash; Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research &amp;amp;ndash; Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. &amp;amp;lt;/p&amp;amp;gt; The seventh volume of this series features these interesting reviews: &amp;amp;lt;/p&amp;amp;gt; - Nucleic acid and peptide aptamers as potential antiviral drugs &amp;amp;lt;/p&amp;amp;gt; - Host-directed, antibiotic-adjuvant combination, and antibiotic-antibiotic combinations for treating multidrug-resistant (mdr) gram-negative pathogens &amp;amp;lt;/p&amp;amp;gt; - Bioactive substances as anti-infective strategies against clostridioides difficile &amp;amp;lt;/p&amp;amp;gt; - Anti-toxoplasma drug discovery and natural products: a brief overview &amp;amp;lt;/p&amp;amp;gt; - Development of antimalarial and antileishmanial drugs from amazonian biodiversity

This text book is a guide for pharmaceutical academics (students and teachers) as well as industry professionals learning about drug delivery and formulation. Chapters presents comprehensive information about self-emulsifying formulations by providing an in-depth understanding of the basic concepts and formulation mechanisms. This information is supplemented by details about current research and development in this field. Readers will learn about the types of self-emulsifying drug delivery systems, evaluation parameters and digestion models, among other topics. </p> Key Features: </p> - 9 chapters organized in a reader-friendly layout </p> - complete guide on self-emulsifying drug delivery formulations, including lipid based systems, SMEDOs, surfactants, and oral dosage forms </p> - includes basic concepts and current developments in research and industrial applications </p> - presents information on conventional and herbal formulations </p> - references for further reading

The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings. </p> This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives. </p> Key Features: </p> Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students. </p> Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19. </p> Six chapters in the first part which focus on clinical basics of COVID-19. </p> Six chapters in the second part which cover broader topics for practical infection control. </p> Multiple tables and figures which summarize and highlight important points. </p> Presents a summary of the current standards for the evaluation and diagnosis of COVID-19. </p> Features a detailed list of references, abbreviations, and symbols. </p> This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.

This handbook explains the application of nanoparticles in medical diagnosis and treatment. It is a ready reference on the subject, starting with the introduction to nanoparticles and progressing to synthetic procedures for nanotherapeutics, human disease diagnosis and nanocarrier-based drug delivery. The book also covers information about specific nanoparticle conjugates, in which nanoparticles are combined with drugs or nucleic acid strands (DNA, siRNAs, shRNAs, miRNAs) as well as topics of relevant to this field such as immunotherapy and vaccination development strategies. Each chapter also provides references for further reading. </p> A Comprehensive Guide to Nanoparticles in Medicine is an ideal resource for scholars in medicine, pharmacology and technology who require an understanding to some basic facets of nanoparticles.

The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings. </p> This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives. </p> Key Features: </p> Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students. </p> Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19. </p> Six chapters in the first part which focus on clinical basics of COVID-19. </p> Six chapters in the first part which cover broader topics for practical infection control. </p> Multiple tables and figures which summarize and highlight important points. </p> Presents a summary of the current standards for the evaluation and diagnosis of COVID-19. </p> Features a detailed list of references, abbreviations, and symbols. </p> This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.

Postbiotics: Science, Technology, and Applications explains fundamental and applied knowledge about postbiotics. Chapters cover the definition and classification of postbiotics, principal methods for preparing them, information about the main postbiotic constituents and their biological activities and their clinical health benefits. The authors also familiarize the reader with potential applications of postbiotics in the food industry, pharmaceutical chemistry, medicine, and veterinary practice. The text is supported by informative illustrations, tables, and references for further reading. This comprehensive reference, with its emphasis on both basic and applied knowledge, is useful for researchers, academics, veterinarians, and students in the field of microbiology, immunology, pharmacology, biotechnology, food science, and agriculture.

The development of a vector for the delivery of therapeutic drugs in a controlled and targeted fashion is still a major challenge in the treatment of many diseases. The conventional application of drugs may lead to many limitations including poor distribution, limited effectiveness, lack of selectivity and dose dependent toxicity. An efficient drug delivery system can address these problems. Recent nanotechnology advancements in the biomedical field have the potential to meet these challenges in developing drug delivery systems. Nanomaterials are changing the biomedical platform in terms of disease diagnosis, treatment and prevention. Nanomaterials aided drug delivery provides an advantage by enhancing aqueous solubility that leads to improved bioavailability, increased resistance time in the body, decreased side effects by targeting drugs to the specific location, reduced dose dependent toxicity and protection of drugs from early release. </p> In this two-part book, the contributors have compiled reports of recent studies illustrating the promising nanomaterials that can work as drug carriers which can navigate conventional physiological barriers. A detailed account of several types of nanomaterials including polymeric nanoparticles, liposomes, dendrimers, micelles, carbon nanomaterials, magnetic nanoparticles, solid lipid-based nanoparticles, silica nanomaterials and hydrogels for drug delivery is provided in separate chapters. The contributors also present a discussion on clinical aspects of ongoing research with insights towards future prospects of specific nanotechnologies. </p> Part II covers the following topics: </p> · Solid lipid nanoparticles and nanostructured lipid carriers </p> · Silica based nanomaterials </p> · Hydrogels </p> · Metallic nanoparticles </p> · Computational and experimental binding interactions of drug and β-cyclodextrin </p> · Clinical milestones in nanotherapeutics </p> · Drug delivery systems based on poly(lactide-co-glycolide) and its copolymers </p> The book set is an informative resource for scholars who seek updates in nanomedicine with reference to nanomaterials used in drug delivery systems.

Current and Future Application of Artificial Intelligence in Clinical Medicine presents updates on the application of machine learning and deep learning techniques in medical procedures. . Chapters in the volume have been written by outstanding contributors from cancer and computer science institutes with the goal of providing updated knowledge to the reader. Topics covered in the book include 1) Artificial Intelligence (AI) applications in cancer diagnosis and therapy, 2) Updates in AI applications in the medical industry, 3) the use of AI in studying the COVID-19 pandemic in China, 4) AI applications in clinical oncology (including AI-based mining for pulmonary nodules and the use of AI in understanding specific carcinomas), 5) AI in medical imaging. Each chapter presents information on related sub topics in a reader friendly format. </p> The combination of expert knowledge and multidisciplinary approaches highlighted in the book make it a valuable source of information for physicians and clinical researchers active in the field of cancer diagnosis and treatment (oncologists, oncologic surgeons, radiation oncologists, nuclear medicine physicians, and radiologists) and computer science scholars seeking to understand medical applications of artificial intelligence.