Advances in the science of immunology have improved the success rate of organ transplantations since the mid twentieth century. Organ transplantation is now a lifesaving medical procedure for thousands of patients around the world with end-organ diseases. The lifesaving potential of transplantation has been limited by the number and quality of appropriate organ donors. The evolution of brain death criteria by the Harvard Ad-Hoc Committee Report has opened the door to understanding the importance of medical, legal and ethical challenges of organ donation in support of the growth of the transplant science. The possibility of organ donation from living donors has enhanced organ availability for patients with kidney failure. Modern inotropes and immunosuppression regimens have been critical to the success of other organ transplant procedures. However, the cornerstone of successful transplantation continues to be the appropriate selection, evaluation, preservation of organ tissues and the successful surgical procurement process to mitigate the impact of tissue ischemia and reperfusion.</p> In this textbook, the art and science of organ donation and tissue preservation is examined. Through this authoritative text by leaders in the field, the editors provide a state of the art review of modern preservation techniques, patient selection and screening criteria, as well as best practices for multi-organ procurement. Information presented in the book will familiarize readers with the initial steps of determining organ availability which ultimately enables health care professionals to realize the extraordinary potential of successful multi-organ transplant procedures. This guide is intended to be a fundamental resource for students, residents, faculty and staff for all disciplines allied to health care delivery and organ donation.

Body contouring is a rapidly growing field within plastic surgery. Safe and effective techniques have been developed in recent times with increased patient satisfaction indicated by visual analogue scores. This book brings together contributions from leading experts in bariatric surgery from all across the globe. The body contouring techniques and procedures described in the book have been developed specifically to treat massive weight loss patients in contrast to traditional methods that are normally unsuitable for such patients. These procedures focus on maximizing the removal of excess and unwanted skin whilst preserving volume and restoring contour. The key issue of patient safety is also addressed in the book. Body Contouring Following Bariatric Surgery and Massive Weight Loss should be a useful resource for surgeons and clinicians interested in massive weight loss surgery and satisfactory visual analogue scores.

With an increase of the population of elderly people in modern society due to advances in medicine and healthcare facilities, there is also an increase in the incidence and duration of chronic illnesses. Similarly, advanced age is considered a significant determinant of depression and poor quality of life. Additionally, the provision of therapies relevant to chronic diseases addresses the issues beyond the concept of cure, bringing to the center the need for a dignified quality of life of patients. An increased interest in quality of life is observed in patients who suffer from chronic diseases, including those with end-stage kidney disease (ESKD). End-stage kidney disease patients have a high burden of disease affecting their quality of life and dramatically shortening their life expectancy. Therefore, exploring quality of life issues among such patients becomes an essential task in the management of this population. This volume is written by researchers with a well-rounded understanding of the characteristics and impact of ESKD and provides a penetrating practical discussion to date of alternative approaches for comprehensively measuring the burden of end-stage kidney disease. Outcomes Assessment in End-Stage Kidney Disease focuses on the impact of this complex and exacting condition on patients and those that care for them. It also examines the economic impact of ESKD and the healthcare policy implications of this disease. It also brings comprehensive and thoughtful insights into the issues confronted by patients with ESKD to readers interested in nursing or medical caregiving, geriatrics and health psychology.

Intelligent Diagnosis of Lung Cancer and Respiratory Diseases presents information about diseases of the respiratory system and the relevant diagnostic imaging techniques. The book focuses on intelligent diagnostic imaging systems. The first section of the book deals with the physiological underpinnings of 3 major diseases that affect the respiratory system: tuberculosis, lung cancer and COVID-19. This section also explains the basic principles of artificial Intelligence that support the diagnosis of these diseases. The next section presents applications of intelligent systems to support the imaging diagnosis of COVID-19 and lung cancer, with emphasis on digital health and telemedicine approaches. Each chapter is organized into a readable format, and is accompanied with a detailed bibliographical information for further reading. This book is a reference for everyone seeking to understand how artificial intelligence can provide solutions for diagnostic support systems by processing and analyzing radiological images to improve early diagnosis and, consequently, lung disease prognosis.

Ischemic cardiomyopathy is considered as the main cause of heart failure in industrialized countries. The condition can occur at any age, but its prevalence increases with age. In general, careful evaluation of the patient's history and physical examination can provide useful information about the underlying causes. Several biomarkers and laboratory variables are very important parameters for physicians during the clinical decision making. Echocardiography along with other imaging and heart failure management techniques can provide key information to clinicians about these parameters. This information can be used to provide adequate medical interventions and improve patient health while reducing the risk of sudden death due to cardiac arrest. This volume of Frontiers in Heart Failure brings forth information about several topics related to assessing the risk of heart failure and treating patients who may be at high risk. Chapters in this volume cover topics such as ischemia, echocardiography, pharmacotherapy, interventional techniques and device therapies. Novel therapies, such as gene and cell strategies are also covered in this volume.

This volume of Frontiers in Heart Failure comprehensively covers the gap between clinical management of heart failure and advanced molecular imaging techniques (SPECT, PET, MRI etc.). These techniques provide valuable evidence to cardiologists for the evaluation and follow-up of heart failure patients. It brings forth established research data regarding the pathophysiology, clinical presentations and therapy of heart failure, in a balance between clinical items and molecular imaging modalities. Readers will also find additional chapters on hybrid cardiovascular imaging techniques as well as guidelines on imaging artifacts and radiation protection. This volume is a useful resource for radiologists, cardiologists, cardiac care nurses and medical physicists.

Pediatric patients require special attention for treating their cardiac conditions and preventing heart failure. Treatment for heart failure in children may involve professionals from multiple medical disciplines. <P></P> Heart Failure in Pediatric Patients describes the pathophysiology, classification and clinical presentation of heart failure in pediatric populations with an emphasis on infants with congenital heart disease. <P></P> Readers will learn about different modes of clinical investigations for pediatric heart patients as well as heart failure in conditions of hypertrophic cardiomyopathy. The book also presents chapters on the management of heart failure including surgery in critical conditions. <P></P> This book explains concepts with interesting images and videos that illustrate and accurately describe cases. it answers the needs of cardiology learners at different levels; undergraduate, postgraduate, specialists and allied professionals who will be able to benefit from the perspective of several cardiologists working at different regional medical centers.

Coronavirus disease 2019 (COVID-19) has affected millions of people across the world. Clinicians and scientists across the globe need all the information of this pandemic on one platform. Today, it is also necessary to find out the association of COVID-19 with various medical comorbidities, and its effect on vulnerable populations that require special medical attention. This information will be helpful for the management of COVID-19. COVID-19: Effects in Comorbidities and Special Populations is a concise and visual reference for information about this viral disease and its relationship with different medical conditions. The book provides comprehensive knowledge covering COVID-19 comorbidities (for example, CVD, Diabetes, lung diseases, etc.), and the incidence in specific groups (for example, children and the elderly). Chapters outline the features and the management of the disease in specific conditions. Key Features: - 12 chapters covering several aspects of COVID-19 management, making this a perfect text book for virologist and medical students - Focused and structured description of different effects of COVID-19 in specific patient groups - Multiple tables and figures which summarizes and highlight important points - Multiple choice questions for learners - Detailed list of references, abbreviations and symbols This book is an essential reference for practicing and training virologists, pulmonologists, medical students and scientists working in research labs, pharmaceutical and biotechnology industries in connection with the control of COVID-19 infection.

This reference summarizes recent advancements in knowledge about cardiovascular disease and pharmacology. The goal of the book is to inform readers about recent findings on cardiovascular therapeutics and how to conduct experiments to evaluate natural products. It presents 10 chapters that cover basic clinical research on cardiovascular diseases and therapeutic agents derived from natural sources. The book concludes with a series of experiments that demonstrate the methods to test the ameliorative effects of 3 phytochemicals: Biochanin A (red clover), Zingiberene (ginger oil) and Betaine (sugar beet). Key Features - 10 chapters that highlight recent research cardiovascular medicine and pharmacology - Covers knowledge about basic cardiovascular physiology, congestive heart failure treatment and the treatment of heart inflammation. - Covers uses, benefits, and drawbacks of numerous rodent and non-rodent animal models for studying CVD - Updates readers about 21st-century CRISPR-cas9 technology and its uses in CVD. - Covers the significance of Indian Ayurvedic techniques on the cardiovascular system, - Covers information about nutraceuticals for CVD therapy - Includes experiments to evaluate 3 phytochemicals for the treatment of different heart diseases such as hypertension, obesity-cardiomyopathy and the mitigation of inflammatory cytokines in myocardial infarction. This book is an informative resource for cardiologists, and researchers working in the field of cardiovascular pharmacology. It also helps readers to understand the benefits of herbal medications that are commonly available for consumption in homes.

This book provides a quick update on key aspects of current anesthesia practice. Book chapters are written in a concise manner to enable readers (anesthesia providers and medical students) to quickly refresh their knowledge, and understand the essential points about key topics. The chapters are written by eminent clinicians who are also outstanding teachers in their respective anesthesia training programs. Topics covered in this volume include: trauma, trauma anesthesia, regional anesthesia, upper extremity blocks, lower extremity blocks, ultrasound, the use of ultrasound for blocks and vascular access, coagulation, hemostasis, transfusion, anticoagulants and their reversal, issues in pediatric anesthesia, and pediatric trauma, as well as obstetrical anesthesia. The book serves as a handbook for advanced anesthesia professionals and a textbook for medical students.