This chapter introduces the covalent and non-covalent intermolecular bonds
as major actors in the basic macromolecule structure. It states the importance of the
ionization energy in bonds and it determines the electronegativity or polarity
quantification as an effective discriminator for the type of bond. With this
quantification amino acids are classified into four groups: polar basic, polar acidic,
polar neutral and non-polar.
Keywords: Bonds, Chemical bonds, Electronegativity, Hydrogen bonds,
Hydrophobic forces, Ionization energy, Intermolecular bonds, Macromolecules,
Polarity, Van der Waals forces, Valence electrons.