Over the past few years, stem cell-based therapeutics has emerged as a promising
strategy for many severe human diseases. The recent studies on stem cells in heart
regeneration have stimulated discoveries directed towards potential clinical applications. A
series of recent advances in signaling pathway and experimental models provide a new
opportunity for the treatment of cardiac diseases. This section will cover the progress made
towards the mechanisms underlying the stem cell development and heart regeneration.
Keywords: Stem cells, heart regeneration, cell therapy, embryonic stem cells,
induced pluripotent stem cells, cardiac progenitor cells.