InsP6 and inositol independently may help in diabetes; InsP6 by stimulating
insulin secretion by the pancreatic β cells. Both inositol and InsP6 can prevent oxidative
damages to the cells and tissues inflicted through advanced glycosylated end products
by acting as antioxidants. InsP6 and inositol could replenish the low intracellular
inositol since they do not need insulin to gain entry into the cell. They also have
positive effect on the abnormalities of fat metabolism such as hypercholesterolemia and
fatty liver.
Keywords: Advanced glycosylated end-products, AGE, cirrhosis, embryopathy,
endothelial dysfunction, fatty liver, gestational diabetes, glycosylated hemoglobin,
hypercholesterolemia, xenobiotics.
