Tissue Development: Molecular Regulation and Signaling Transduction (from Gene to Human)

Pp: 12-23 (12)

* (Excluding Mailing and Handling)

Abstract

Every human is a result of a cell formed from the fertilization of an oocyte with a sperm. This cell is called a zygote. A miracle is how just one cell can make a lot of tissues and organs. Regulation of gene expression is the first step of tissue development. Regulation of gene expression has different levels, including the genome (DNA content), transcriptome (RNA content, resulted from the transcription of DNA), and proteome (protein content, resulted from the translation of RNA) levels. The final consequence of gene expression regulation is cellular phenotype. The resulted proteins act for inter-cellular signaling transduction and tissue development. We aimed to show the details of gene expression regulation, cellular signaling transduction and interaction, and tissue development. We have shown a scheme of the gene to fetus formation.

Keywords: Tissue development, Signaling transduction, Gene expression regulation.

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