Neurodegenerative disease (ND) is a progressive neurological condition that
leads to damage to the neuronal connection essential for various sensory, motor and
cognitive functions. Neurotrauma (NT) is an external injury to the brain or spinal cord.
The incidence and prevalence of ND and NT are alarmingly increasing owing to
several factors such as food intake, modern lifestyle, increased life expectancy and
several other comorbid conditions. The identification of novel materials that can cross
the BBB and delay or deny the onset and progress of neuropathophysiology of ND is
essential. Perovskite, a nanomaterial with some specific characteristics such as
semiconducting, photoemitting, photothermal, ferromagnetic and cations exchange
properties, fosters the need for further exploration in the treatment of NDs and
neurotrauma (NT). With subsequent research, the toxic side effects of perovskite are
also minimized with the synthesis of lead-free perovskite. Various computational
models, such as neuro-morphic networking, are used to explore the ability of
perovskites to facilitate neural synapsis in NDs and NT. Potential identification of the
novel pathway of ND directs in modifying the strategic intervention of ND. Initial
findings regarding the application of perovskites in the treatment of NDs and NT have
shown promising outcomes that need further exploration.
Keywords: Neurodegenerative Disorders, Neural Networks, Neurotrauma, Perovskites.
