In poor nations, helminthic illnesses are a major source of social, economic,
and medical problems. These parasite illnesses affect a large number of people, and
there are not enough effective treatments available. It is necessary to step up research
on novel medications and treatments to address this pressing need. The lymphatic
system is hampered by lymphatic filariasis, which can result in aberrant body part
growth and cause discomfort, severe disability, and social stigma. As of 2018, there
were 51 million cases, a 74% decrease from the 2000 commencement of the WHO's
Global Programme to Eradicate Lymphatic Filariasis. With 27 cases documented in
2020, the devastating parasite disease dracunculiasis is almost completely eradicated.
The transmission cycle takes between 10 and 14 months to complete after infection.
The aim of the book chapter is to focus on pathogenesis, diagnosis, available treatment,
and measures to eradicate these infections caused by helminthic parasites, which have
been declared as neglected diseases by the World Health Organization.
Keywords: Dracunculiasis, Helminthic disease, Lymphatic filariasis, Neglected disease, WHO.