Breast cancer (BC) is the most common among females. The current status
of BC worldwide shows that more than 1 million women are affected and ~400 000 die
every year. Partial success has been achieved by mammography coupled with adjuvant
treatment. However, its incidence and mortality both are increasing. Several subcategories of BC have been reported; of which, one is triple-negative breast cancer
(TNBC). This is defined by a lack of expression of oestrogen and progesterone
receptors and human epidermal growth factor receptor 2 (HER-2). Several approaches
have been used for speedy and accurate diagnosis and precise treatment of BC. In this
context, precision medicine approach is of great relevance in ameliorating the suffering
of the patient’s from the menace of BC. The present chapter aims to provide
background information, different types of BC and its sub-types and molecular
mechanisms for therapeutic intervention required for precision medicine.
Keywords: Breast cancer, Human epidermal growth factor receoptor-2 (HER-2), Triple-negative breast cancer, Therapeutic intervention.
