The significant potential of thiazole and thiazolidinone derivatives as antiinflammatory drugs can be observed in their ability to inhibit a variety of inflammatory
mediators. These derivatives also inhibit factors that catalyze the synthesis of
inflammatory mediators. The anti-inflammatory effects of the derivatives of thiazole
and thiazolidinone demonstrated this potential. In addition, they have antioxidant
properties that help to reduce oxidative stress and inflammation that the body
experiences. These derivatives represent promising molecules for the development of
new medications in the near future because they successfully reduce inflammation in
various preclinical and clinical studies. The potential of thiazole derivatives as COX
inhibitors and anti-inflammatory drugs has also been investigated, with promising
results. Further research is needed to explore their mechanisms of action, optimize their
therapeutic potential, and evaluate their safety and efficacy in clinical settings.
Keywords: Anti-inflammatory agents, COX1, COX2, NASIDs, Thiazole, Thiazolidinone.
