Non-invasive management of initial enamel lesions using novel
remineralizing agents has become the main goal of modern dentistry. Herbs and natural
sources with medicinal properties are valuable for treating various oral diseases.
Fluoride-mediated remineralization is the cornerstone of caries management. However,
many side effects arise from its use, such as dental fluorosis. Most people could accept
natural remineralizing agents compared to fluoride-based remineralizing systems. The
trend is to use natural ingredients as remineralizing agents to control caries. Different
naturally derived agents have been found to remineralize the demineralized enamel
lesions efficiently and to prevent caries progression. The growing interest in
phytotherapeutics is due to the active biological components of plant extracts and
natural products. The active biological components in plants, eggshells, seashells, and
other natural products play a significant role in enamel remineralization. Herbal
extracts and natural products with remineralizing effects are added to dentifrice and
mouthwashes to prevent caries or to enhance the remineralization of initial lesion
enamel lesions.
Keywords: Aloe vera, Animal-based remineralizing agents, Biologically derived materials, Caries prevention, Cinnamon, Demineralization, Eggshells, Enamel remineralization, Fluoride, Ginger, Grape seed extract, Herbal extracts, Marinebased remineralizing agents, Minimal Invasive Dentistry, Moringa oleifera, Natural products, Non cavitated enamel lesions, Propolis, Seashells, Tea.
