Materials with specific properties and structures are required for 3D
nanofibers scaffold to perform well during tissue regeneration and drug delivery
applications. When designing and fabricating 3D scaffolds, it is crucial to consider how
the biomaterials interact with the native tissue structures and how they function in the
surrounding environment. This chapter provided a brief discussion on the fabrication
methods used to construct 3D biodegradable polymeric nanofibers scaffolds through
electrospinning from 2D structures. Further, it extended to the characterisation required
for the scaffold to be used in either tissue engineering or drug delivery. Additionally,
this chapter presented recent progress in the practical application of 3D scaffolds that
incorporate different therapeutic agents.
Keywords: 3D scaffold, Electrospinning, Nanofibers, Tissue regenerations, Drug delivery.
