A constellation of specific personal characteristics of the patients have been
described as personomics, which involves an individual patient’s personality type, set
of personal values, priorities, preferences, health-related beliefs, goals, economic
status, and different life circumstances, which can affect when and how a certain
disease (e.g., breast cancer (BC)) can be manifested in a given woman.
As a consequence, personomics can be considered to be a novel clinical instrument
that is helpful for making a connection between the standard and the emerging, more
individualized model of medical care. This plays an essential role in patients
diagnosed with the most aggressive and difficult-to-treat malignancies (e.g., BC
subtypes, such as triple-negative breast cancer (TNBC).
At present, many biological properties in the forms of different “omics” platforms
(such as genomics, proteomics, transcriptomics, metabolomics, epigenomics, and
pharmacogenomics) have emerged. They have been incorporated into precision
medicine. However, to optimally tailor diagnostic and therapeutic approaches to a
given patient, the biological characteristics need to be integrated with the personal
ones.
This chapter aims to address some practical research ideas of personalized medicine,
relevant to personomics that can incorporate individual patient issues into the
comprehensive therapeutic plan.
Keywords: Breast cancer (BC), Precision medicine, Personomics, Patientcentered approach, Personalized medical care, Triple-negative breast cancer (TNBC).
