Recently, many new methods have been used in the research and
development of a new drug. In this article, QSAR, which is one of the usable areas of
artificial intelligence during molecule research, and the analysis and formulation
studies related to the suitability of this area are discussed. It is explained how a model
to be created is prepared and calculation formulas for how to verify this model are
shown. Examples of the most recent 4D-QSAR calculations are given.
Keywords: Molecular Modelling, Pharmacophore, QSAR, Quantitative Structure-activity Relationship, Validation.
