Scabies is a chronic and serious community disorder caused by a parasite
commonly known as a mite (Sarcoptes scabiei var hominis). The long-term infection
may lead to chronic complications such as septicemia, acute post-streptococcal
glomerulonephritis, heart disease, and secondary infections. The majority of novel
medicinal agents from various plant sources are responsible for the management and
treatment of several types of chronic disorders. The safe and cost-effective alternative
treatment strategy is the use of medicinal plants that plays a potential role against a
variety of diseases due to the presence of numerous types of active phytochemicals
with no or negligible adverse effect. This study gives a unique summary, including a
correlation between traditional medicinal plants and their derived active
phytochemicals for the significant treatment of scabies. The literature search was
carried out via search engines through different databases, including Google Scholar,
PubMed, Medline, ScienceDirect, etc. A large number of medicinal plants and their
active medicinal agents have been reviewed with remarkable therapeutic effects against
scabies. There are some limitations due to insufficient data related to limited pre-clinical and clinical trials in this particular area. This review provides a baseline to
explore the therapeutic potential of these medicinal plants against skin diseases,
especially scabies. However, extensive studies are required to identify, authenticate,
and characterize the bioactive compounds present in these plants, which may lead to
value addition in pharmaceutical industries by providing a cost-effective way of
treatment with minimal side effects.
Keywords: Burrows, Clinical Study, Epidemiology, Future Prospective, Herbal Medicines, Mites, Natural Products, Skin diseases, Scabies, Sarcoptes scabiei var hominis, Therapeutic Agents, Transmission, World Health Organization.
