Wound healing is quite a complicated process in the human body, consisting
of the action of constricting injured blood vessels, activating the immune system,
angiogenesis, remodeling, etc. Under intensive mechanical stress, a fibrotic scar, which
is unfavorable with respect to the beauty of the skin, can be formed to patch the wound.
Moreover, chronic wounds due to the disruption in wound healing are another clinical
problem for patients with diabetes or vascular diseases. Of note is that natural
remedies, especially natural products, are demonstrated to elicit certain positive effects
on many aspects of wound healing. In this chapter, global mechanisms, the role of
natural remedies and newly emerging therapeutic targets regarding wound healing are
presented, and the remaining hurdle for the natural product-based treatment in wound
healing is also introduced.
Keywords: Non-coding RNAs, Diabetes, Fibrotic scar, Natural products, Skin, Wound healing.
