Abstract
Superparamagnetic iron oxide nanoparticles have attracted attention due to
their compatibility with various biomedical applications. The quantum confinement
and increased surface area to volume ratio of the nanostructures alter their magnetic
properties. There are several bottom-up techniques to synthesize superparamagnetic
iron oxide nanoparticles; however, they offer certain limitations, like the existence of a
secondary phase. The reaction parameters can be controlled to form pure-phase
nanoparticles to increase their scope of applications in the field of medicine. Moreover,
different applications demand different surface coatings of iron oxide nanoparticles.
Keywords: Drug delivery, Hyperthermia, Iron oxide, In vitro, Nanostructures, Superparamagnetism.
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