Polycystic ovary syndrome (PCOS) is one of the most common
gynecological disorders among women of reproductive age. The secretion rate and
metabolism of estrogens and androgens are disrupted in patients with PCOS. Patients
have systemic inflammation, hyperinsulinemia, hyperandrogenism, and polycystic
ovaries. Several experimental models have been developed and studied for the
investigation of this disease. These studies aim to explore the pathophysiology of
PCOS and new treatment approaches. Some plant extracts and phytochemicals
obtained from them are shown to be effective against PCOS in literature. In this
chapter, general information about PCOS, plant-based treatment approaches, and
activity methods are explained in detail.
Keywords: Animal models, activity methods, gynecological disease, medicinal plants, natural products, polycystic ovarian syndrome.
