Immunity is the inherent ability of the body to fight against various infections, and foreign invaders. When the host body comes in contact with a foreign body, a series of chemical mediators are released, which collectively elicit an immune response. The biomolecules capable of stimulating, suppressing and modulating innate or acquired immunity, biological or synthetic in origin, are termed as immunomodulators or immunoaugmentors. Limited clinical use of synthetic immunomodulators has attracted the attention of researchers toward immunomodulatory characteristics of natural therapeutics. Though natural immunomodulators render their efficacy in several chronic illnesses, there are challenges that need to be addressed and resolved to make them viable alternate therapeutics. This chapter highlights the challenges and future perspectives of natural immunomodulators.
Keywords: Adaptive Immunity, Future Challenges, Innate Immunity, Immunomodulators, Novel Drug Delivery, Perspective of Immunomodulators.